Action myoclonus-renal failure syndrome: diagnostic applications of activity-based probes and lipid analysis

by Paulo Gaspar, Wouter W. Kallemeijn, Anneke Strijland, Saskia Scheij, Marco Van Eijk, Jan Aten, Herman S. Overkleeft, Andrea Balreira, Friederike Zunke, Michael Schwake, Clara Sá Miranda, JohannesM.F.G. Aerts
Published 2014-01-01

Roles of glomerular endothelial hyaluronan in the development of proteinuria

by Akimasa Asai, Naoyuki Hatayama, Keisuke Kamiya, Mai Yamauchi, Hiroshi Kinashi, Makoto Yamaguchi, Takayuki Katsuno, Hironobu Nobata, Kazushi Watanabe, Akihiko Wakatsuki, Jan Aten, Shoichi Maruyama, Takuji Ishimoto, Shuichi Hirai, Munekazu Naito, Yasuhiko Ito
Published 2021-09-01

Gpnmb Is a Potential Marker for the Visceral Pathology in Niemann-Pick Type C Disease.

by André R A Marques, Tanit L Gabriel, Jan Aten, Cindy P A A van Roomen, Roelof Ottenhoff, Nike Claessen, Pilar Alfonso, Pilar Irún, Pilar Giraldo, Johannes M F G Aerts, Marco van Eijk
Published 2016-01-01

Distinct osmoregulatory responses to sodium loading in patients with altered glycosaminoglycan structure: a randomized cross-over trial

by Eliane F. E. Wenstedt, Jetta J. Oppelaar, Stijn Besseling, Nienke M. G. Rorije, Rik H. G. Olde Engberink, Arie Oosterhof, Toin H. van Kuppevelt, Bert-Jan H. van den Born, Jan Aten, Liffert Vogt
Published 2021-01-01

Correction of liver steatosis by a hydrophobic iminosugar modulating glycosphingolipids metabolism.

by Elisa Lombardo, Cindy P A A van Roomen, Gijs H van Puijvelde, Roelof Ottenhoff, Marco van Eijk, Jan Aten, Johan Kuiper, Herman S Overkleeft, Albert K Groen, Arthur J Verhoeven, Johannes M F G Aerts, Florence Bietrix
Published 2012-01-01

GCase and LIMP2 Abnormalities in the Liver of Niemann Pick Type C Mice

by Martijn J. C. van der Lienden, Jan Aten, André R. A. Marques, Ingeborg S. E. Waas, Per W. B. Larsen, Nike Claessen, Nicole N. van der Wel, Roelof Ottenhoff, Marco van Eijk, Johannes M. F. G. Aerts
Published 2021-03-01

Reducing glycosphingolipid content in adipose tissue of obese mice restores insulin sensitivity, adipogenesis and reduces inflammation.

by Marco van Eijk, Jan Aten, Nora Bijl, Roelof Ottenhoff, Cindy P A A van Roomen, Peter F Dubbelhuis, Ingar Seeman, Karen Ghauharali-van der Vlugt, Hermen S Overkleeft, Cynthia Arbeeny, Albert K Groen, Johannes M F G Aerts
Published 2009-01-01

Elevated Urinary Connective Tissue Growth Factor in Diabetic Nephropathy Is Caused by Local Production and Tubular Dysfunction

by Karin G. F. Gerritsen, Jan Willem Leeuwis, Maarten P. Koeners, Stephan J. L. Bakker, Willem van Oeveren, Jan Aten, Lise Tarnow, Peter Rossing, Jack F. M. Wetzels, Jaap A. Joles, Robbert Jan Kok, Roel Goldschmeding, Tri Q. Nguyen
Published 2015-01-01

Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice.

by André R A Marques, Jan Aten, Roelof Ottenhoff, Cindy P A A van Roomen, Daniela Herrera Moro, Nike Claessen, María Fernanda Vinueza Veloz, Kuikui Zhou, Zhanmin Lin, Mina Mirzaian, Rolf G Boot, Chris I De Zeeuw, Herman S Overkleeft, Yildiz Yildiz, Johannes M F G Aerts
Published 2015-01-01

Visualization of Active Glucocerebrosidase in Rodent Brain with High Spatial Resolution following In Situ Labeling with Fluorescent Activity Based Probes.

by Daniela Herrera Moro Chao, Wouter W Kallemeijn, Andre R A Marques, Marie Orre, Roelof Ottenhoff, Cindy van Roomen, Ewout Foppen, Maria C Renner, Martina Moeton, Marco van Eijk, Rolf G Boot, Willem Kamphuis, Elly M Hol, Jan Aten, Hermen S Overkleeft, Andries Kalsbeek, Johannes M F G Aerts
Published 2015-01-01