The Mitochondrial Genes <i>BAK1</i>, <i>FIS1</i> and <i>SFN</i> are Linked with Alterations in Mitochondrial Membrane Potential in Barrett’s Esophagus

by James J. Phelan, Finbar MacCarthy, Dermot O’Toole, Narayanasamy Ravi, John V. Reynolds, Jacintha O’Sullivan
Published 2018-11-01

Modulating Iron for Metabolic Support of TB Host Defense

by James J. Phelan, Sharee A. Basdeo, Simone C. Tazoll, Sadhbh McGivern, Judit R. Saborido, Joseph Keane
Published 2018-10-01

The Warburg Effect Occurs Rapidly in Stimulated Human Adult but Not Umbilical Cord Blood Derived Macrophages

by Cilian Ó Maoldomhnaigh, Donal J. Cox, James J. Phelan, Fergal D. Malone, Joseph Keane, Sharee A. Basdeo
Published 2021-04-01

Inhibiting Histone Deacetylases in Human Macrophages Promotes Glycolysis, IL-1β, and T Helper Cell Responses to Mycobacterium tuberculosis

by Donal J. Cox, Amy M. Coleman, Karl M. Gogan, James J. Phelan, Cilian Ó Maoldomhnaigh, Pádraic J. Dunne, Sharee A. Basdeo, Joseph Keane
Published 2020-07-01

Differential Expression Profiles of Oxidative Stress Levels, 8-oxo-dG and 4-HNE, in Barrett’s Esophagus Compared to Esophageal Adenocarcinoma

by Naoimh J. O’Farrell, James J. Phelan, Ronan Feighery, Brendan Doyle, Sarah L. Picardo, Narayanasamy Ravi, Dermot O’Toole, John V. Reynolds, Jacintha O’Sullivan
Published 2019-09-01

The Iron Chelator Desferrioxamine Increases the Efficacy of Bedaquiline in Primary Human Macrophages Infected with BCG

by Christina Cahill, Fiona O’Connell, Karl M. Gogan, Donal J. Cox, Sharee A. Basdeo, Jacintha O’Sullivan, Stephen V. Gordon, Joseph Keane, James J. Phelan
Published 2021-03-01

Lactate Alters Metabolism in Human Macrophages and Improves Their Ability to Kill Mycobacterium tuberculosis

by Cilian Ó Maoldomhnaigh, Donal J. Cox, James J. Phelan, Morgane Mitermite, Dearbhla M. Murphy, Gina Leisching, Lorraine Thong, Seónadh M. O’Leary, Karl M. Gogan, Kate McQuaid, Amy M. Coleman, Stephen V. Gordon, Sharee A. Basdeo, Joseph Keane
Published 2021-10-01

The Prognostic Value of the Lymph Node in Oesophageal Adenocarcinoma; Incorporating Clinicopathological and Immunological Profiling

by Noel E. Donlon, Maria Davern, Andrew Sheppard, Robert Power, Fiona O’Connell, Aisling B. Heeran, Ross King, Conall Hayes, Anshul Bhardwaj, James J. Phelan, Margaret R. Dunne, Narayanasamy Ravi, Claire L. Donohoe, Jacintha O’Sullivan, John V. Reynolds, Joanne Lysaght
Published 2021-08-01

Linking Circulating Serum Proteins with Clinical Outcomes in Esophageal Adenocarcinoma—An Emerging Role for Chemokines

by Noel E. Donlon, Andrew Sheppard, Maria Davern, Fiona O’Connell, James J. Phelan, Robert Power, Timothy Nugent, Kate Dinneen, John Aird, John Greene, Paul Nevins Selvadurai, Anshul Bhardwaj, Emma K. Foley, Narayanasamy Ravi, Claire L. Donohoe, John V. Reynolds, Joanne Lysaght, Jacintha O’Sullivan, Margaret R. Dunne
Published 2020-11-01

Mucosal-Associated Invariant T Cells Display Diminished Effector Capacity in Oesophageal Adenocarcinoma

by Ashanty M. Melo, Aisling M. O'Brien, James J. Phelan, Susan A. Kennedy, Nicole A. W. Wood, Natacha Veerapen, Gurdyal S. Besra, Niamh E. Clarke, Emma K. Foley, Akshaya Ravi, Finbar MacCarthy, Dermot O'Toole, Narayamasami Ravi, Narayamasami Ravi, John V. Reynolds, John V. Reynolds, Melissa J. Conroy, Andrew E. Hogan, Andrew E. Hogan, Jacintha O'Sullivan, Margaret R. Dunne
Published 2019-07-01