A rare case of acquired immunodeficiency associated with myelodysplastic syndrome

by Juanjuan Li, Junhui Li, Jianguo Li, Hailan Yao, Fang Liu, James F Gusella, Xiaodong Shi, Xiaoli Chen
Published 2019-11-01

Deficiency of huntingtin has pleiotropic effects in the social amoeba Dictyostelium discoideum.

by Michael A Myre, Amanda L Lumsden, Morgan N Thompson, Wilma Wasco, Marcy E MacDonald, James F Gusella
Published 2011-04-01

Mutant Huntingtin Forms in Vivo Complexes with Distinct Context-Dependent Conformations of the Polyglutamine Segment

by Francesca Persichetti, Flavia Trettel, C.Chris Huang, Cornel Fraefel, H.T.Marc Timmers, James F. Gusella, Marcy E. MacDonald
Published 1999-10-01

Correction: dtorsin, the Drosophila Ortholog of the Early-Onset Dystonia TOR1A (DYT1), Plays a Novel Role in Dopamine Metabolism

by Noriko Wakabayashi-Ito, Olugbenga M. Doherty, Hideaki Moriyama, Xandra O. Breakefield, James F. Gusella, Janis M. O'Donnell, Naoto Ito
Published 2011-01-01

Dtorsin, the Drosophila ortholog of the early-onset dystonia TOR1A (DYT1), plays a novel role in dopamine metabolism.

by Noriko Wakabayashi-Ito, Olugbenga M Doherty, Hideaki Moriyama, Xandra O Breakefield, James F Gusella, Janis M O'Donnell, Naoto Ito
Published 2011-01-01

Unbiased gene expression analysis implicates the huntingtin polyglutamine tract in extra-mitochondrial energy metabolism.

by Jong-Min Lee, Elena V Ivanova, Ihn Sik Seong, Tanya Cashorali, Isaac Kohane, James F Gusella, Marcy E MacDonald
Published 2007-08-01

Correction: , the Ortholog of the Early-Onset Dystonia (), Plays a Novel Role in Dopamine Metabolism.

by Noriko Wakabayashi-Ito, Olugbenga M. Doherty, Hideaki Moriyama, Xandra O. Breakefield, James F. Gusella, Janis M. O'Donnell, Naoto Ito
Published 2011-01-01

Modeling NF2 with human arachnoidal and meningioma cell culture systems: NF2 silencing reflects the benign character of tumor growth

by Marianne F. James, Johanna M. Lelke, Mia MacCollin, Scott R. Plotkin, Anat O. Stemmer-Rachamimov, Vijaya Ramesh, James F. Gusella
Published 2008-02-01

Mediator Subunit Med28 Is Essential for Mouse Peri-Implantation Development and Pluripotency.

by Lin Li, Ryan M Walsh, Vilas Wagh, Marianne F James, Roberta L Beauchamp, Yuh-Shin Chang, James F Gusella, Konrad Hochedlinger, Vijaya Ramesh
Published 2015-01-01

Brain-derived neurotrophic factor does not influence age at neurologic onset of Huntington’s disease

by Shotaro Kishikawa, Jian-Liang Li, Tammy Gillis, Michael M. Hakky, Simon Warby, Michael Hayden, Marcy E. MacDonald, Richard H. Myers, James F. Gusella
Published 2006-11-01

HD CAGnome: a search tool for huntingtin CAG repeat length-correlated genes.

by Ekaterina I Galkina, Aram Shin, Kathryn R Coser, Toshi Shioda, Isaac S Kohane, Ihn Sik Seong, Vanessa C Wheeler, James F Gusella, Marcy E Macdonald, Jong-Min Lee
Published 2014-01-01

16p11.2 deletion is associated with hyperactivation of human iPSC-derived dopaminergic neuron networks and is rescued by RHOA inhibition in vitro

by Maria Sundberg, Hannah Pinson, Richard S. Smith, Kellen D. Winden, Pooja Venugopal, Derek J. C. Tai, James F. Gusella, Michael E. Talkowski, Christopher A. Walsh, Max Tegmark, Mustafa Sahin
Published 2021-05-01

Huntington's disease CAG trinucleotide repeats in pathologically confirmed post-mortem brains

by Francesca Persichetti, Jayalakshmi Srinidhi, Lisa Kanaley, Pei Ge, Richard H. Myers, Kenneth D'Arrigo, Glenn T. Barnes, Marcy E. MacDonald, Jean-Paul Vonsattel, James F. Gusella, Edward D. Bird
Published 1994-12-01

MicroRNAs located in the Hox gene clusters are implicated in huntington's disease pathogenesis.

by Andrew G Hoss, Vinay K Kartha, Xianjun Dong, Jeanne C Latourelle, Alexandra Dumitriu, Tiffany C Hadzi, Marcy E Macdonald, James F Gusella, Schahram Akbarian, Jiang-Fan Chen, Zhiping Weng, Richard H Myers
Published 2014-02-01

Correction: RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression.

by Adam Labadorf, Andrew G Hoss, Valentina Lagomarsino, Jeanne C Latourelle, Tiffany C Hadzi, Joli Bregu, Marcy E MacDonald, James F Gusella, Jiang-Fan Chen, Schahram Akbarian, Zhiping Weng, Richard H Myers
Published 2016-01-01

RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression.

by Adam Labadorf, Andrew G Hoss, Valentina Lagomarsino, Jeanne C Latourelle, Tiffany C Hadzi, Joli Bregu, Marcy E MacDonald, James F Gusella, Jiang-Fan Chen, Schahram Akbarian, Zhiping Weng, Richard H Myers
Published 2015-01-01

Detection of copy number variants reveals association of cilia genes with neural tube defects.

by Xiaoli Chen, Yiping Shen, Yonghui Gao, Huizhi Zhao, Xiaoming Sheng, Jizhen Zou, Va Lip, Hua Xie, Jin Guo, Hong Shao, Yihua Bao, Jianliang Shen, Bo Niu, James F Gusella, Bai-Lin Wu, Ting Zhang
Published 2013-01-01

Hypomorphic mutation of the mouse Huntington's disease gene orthologue.

by Vidya Murthy, Toma Tebaldi, Toshimi Yoshida, Serkan Erdin, Teresa Calzonetti, Ravi Vijayvargia, Takshashila Tripathi, Emanuela Kerschbamer, Ihn Sik Seong, Alessandro Quattrone, Michael E Talkowski, James F Gusella, Katia Georgopoulos, Marcy E MacDonald, Marta Biagioli
Published 2019-03-01

Transcriptional consequences of MBD5 disruption in mouse brain and CRISPR-derived neurons

by Catarina M. Seabra, Tatsiana Aneichyk, Serkan Erdin, Derek J. C. Tai, Celine E. F. De Esch, Parisa Razaz, Yu An, Poornima Manavalan, Ashok Ragavendran, Alexei Stortchevoi, Clemer Abad, Juan I. Young, Patricia Maciel, Michael E. Talkowski, James F. Gusella
Published 2020-06-01

Population-specific genetic modification of Huntington's disease in Venezuela.

by Michael J Chao, Kyung-Hee Kim, Jun Wan Shin, Diane Lucente, Vanessa C Wheeler, Hong Li, Jared C Roach, Leroy Hood, Nancy S Wexler, Laura B Jardim, Peter Holmans, Lesley Jones, Michael Orth, Seung Kwak, Marcy E MacDonald, James F Gusella, Jong-Min Lee
Published 2018-05-01