Expression of iron homeostasis proteins in the spinal cord in experimental autoimmune encephalomyelitis and their implications for iron accumulation

by Juan G. Zarruk, Jennifer L. Berard, Rosmarini Passos dos Santos, Antje Kroner, Jaekwon Lee, Paolo Arosio, Samuel David
Published 2015-09-01

Urinary copper elevation in a mouse model of Wilson's disease is a regulated process to specifically decrease the hepatic copper load.

by Lawrence W Gray, Fangyu Peng, Shannon A Molloy, Venkata S Pendyala, Abigael Muchenditsi, Otto Muzik, Jaekwon Lee, Jack H Kaplan, Svetlana Lutsenko
Published 2012-01-01

Iron insufficiency compromises motor neurons and their mitochondrial function in Irp2-null mice.

by Suh Young Jeong, Daniel R Crooks, Hayden Wilson-Ollivierre, Manik C Ghosh, Rachid Sougrat, Jaekwon Lee, Sharon Cooperman, James B Mitchell, Carole Beaumont, Tracey A Rouault
Published 2011-01-01

Overexpression of alpha-synuclein at non-toxic levels increases dopaminergic cell death induced by copper exposure via modulation of protein degradation pathways

by Annadurai Anandhan, Humberto Rodriguez-Rocha, Iryna Bohovych, Amy M. Griggs, Laura Zavala-Flores, Elsa M. Reyes-Reyes, Javier Seravalli, Lia A. Stanciu, Jaekwon Lee, Jean-Christophe Rochet, Oleh Khalimonchuk, Rodrigo Franco
Published 2015-09-01

Lysosomal SLC46A3 modulates hepatic cytosolic copper homeostasis

by Jung-Hwan Kim, Tsutomu Matsubara, Jaekwon Lee, Cristina Fenollar-Ferrer, Kyungreem Han, Donghwan Kim, Shang Jia, Christopher J. Chang, Heejung Yang, Tomokazu Nagano, Kristopher W. Krausz, Sun-Hee Yim, Frank J. Gonzalez
Published 2021-01-01

Sestrin2 Phosphorylation by ULK1 Induces Autophagic Degradation of Mitochondria Damaged by Copper-Induced Oxidative Stress

by Heejeong Kim, Byeong Tak Jeon, Isaac M. Kim, Sydney J. Bennett, Carolyn M. Lorch, Martonio Ponte Viana, Jacob F. Myers, Caroline J. Trupp, Zachary T. Whipps, Mondira Kundu, Soonkyu Chung, Xinghui Sun, Oleh Khalimonchuk, Jaekwon Lee, Seung-Hyun Ro
Published 2020-08-01