What Has the Study of the K3 and K5 Viral Ubiquitin E3 Ligases Taught Us about Ubiquitin-Mediated Receptor Regulation?

by Paul J. Lehner, Jessica M. Boname
Published 2011-01-01

Machine learning analysis of lifeguard flag decisions and recorded rescues

by C. Houser, J. Lehner, N. Cherry, P. Wernette
Published 2019-11-01

Antibody-free magnetic cell sorting of genetically modified primary human CD4+ T cells by one-step streptavidin affinity purification.

by Nicholas J Matheson, Andrew A Peden, Paul J Lehner
Published 2014-01-01

Clinical presentation of multiple cerebral emboli and central retinal artery occlusion (CRAO) as signs of cardiac myxoma

by Alberto Galvez-Ruiz, Alicia Galindo-Ferreiro, Anthony J. Lehner, Igor Kozac
Published 2018-04-01

A 58-year-old woman with abdominal symptoms and elevated C-reactive protein.

by Marie-Louise Daly, David J Cartwright, Paul J Lehner, Babak Javid
Published 2008-07-01

ATF7IP-Mediated Stabilization of the Histone Methyltransferase SETDB1 Is Essential for Heterochromatin Formation by the HUSH Complex

by Richard T. Timms, Iva A. Tchasovnikarova, Robin Antrobus, Gordon Dougan, Paul J. Lehner
Published 2016-10-01

A genome-wide CRISPR screen identifies regulation factors of the TLR3 signalling pathway

by Laurent Zablocki-Thomas, Sam A Menzies, Paul J Lehner, Nicolas Manel, Philippe Benaroch
Published 2020-08-01

Functional proteomic atlas of HIV infection in primary human CD4+ T cells

by Adi Naamati, James C Williamson, Edward JD Greenwood, Sara Marelli, Paul J Lehner, Nicholas J Matheson
Published 2019-03-01

No evidence for basigin/CD147 as a direct SARS-CoV-2 spike binding receptor

by Jarrod Shilts, Thomas W. M. Crozier, Edward J. D. Greenwood, Paul J. Lehner, Gavin J. Wright
Published 2021-01-01

Fluorescence-based phenotypic selection allows forward genetic screens in haploid human cells.

by Lidia M Duncan, Richard T Timms, Eszter Zavodszky, Florencia Cano, Gordon Dougan, Felix Randow, Paul J Lehner
Published 2012-01-01

Promiscuous Targeting of Cellular Proteins by Vpr Drives Systems-Level Proteomic Remodeling in HIV-1 Infection

by Edward J.D. Greenwood, James C. Williamson, Agata Sienkiewicz, Adi Naamati, Nicholas J. Matheson, Paul J. Lehner
Published 2019-04-01

Neuropathic MORC2 mutations perturb GHKL ATPase dimerization dynamics and epigenetic silencing by multiple structural mechanisms

by Christopher H. Douse, Stuart Bloor, Yangci Liu, Maria Shamin, Iva A. Tchasovnikarova, Richard T. Timms, Paul J. Lehner, Yorgo Modis
Published 2018-02-01

The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1

by Sam A Menzies, Norbert Volkmar, Dick JH van den Boomen, Richard T Timms, Anna S Dickson, James A Nathan, Paul J Lehner
Published 2018-12-01

Temporal proteomic analysis of HIV infection reveals remodelling of the host phosphoproteome by lentiviral Vif variants

by Edward JD Greenwood, Nicholas J Matheson, Kim Wals, Dick JH van den Boomen, Robin Antrobus, James C Williamson, Paul J Lehner
Published 2016-09-01

Haploid genetic screens identify an essential role for PLP2 in the downregulation of novel plasma membrane targets by viral E3 ubiquitin ligases.

by Richard T Timms, Lidia M Duncan, Iva A Tchasovnikarova, Robin Antrobus, Duncan L Smith, Gordon Dougan, Michael P Weekes, Paul J Lehner
Published 2013-01-01

CD97 stabilises the immunological synapse between dendritic cells and T cells and is targeted for degradation by the Salmonella effector SteD.

by Ondrej Cerny, Camilla Godlee, Romina Tocci, Nancy E Cross, Haoran Shi, James C Williamson, Eric Alix, Paul J Lehner, David W Holden
Published 2021-07-01

Antagonism of PP2A is an independent and conserved function of HIV-1 Vif and causes cell cycle arrest

by Sara Marelli, James C Williamson, Anna V Protasio, Adi Naamati, Edward JD Greenwood, Janet E Deane, Paul J Lehner, Nicholas J Matheson
Published 2020-04-01

Genetic dissection of mammalian ERAD through comparative haploid and CRISPR forward genetic screens

by Richard T. Timms, Sam A. Menzies, Iva A. Tchasovnikarova, Lea C. Christensen, James C. Williamson, Robin Antrobus, Gordon Dougan, Lars Ellgaard, Paul J. Lehner
Published 2016-06-01

Analysis of Risk Factors and Long-Term Outcomes in Kidney Transplant Patients with Identified Lymphoceles

by Lukas J. Lehner, Arnim Hohberger, Lisanne Marschke, Nils Lachmann, Robert Peters, Frank Friedersdorff, Dmytro Khadzhynov, Fabian Halleck, Klemens Budde, Oliver Staeck, Michael Duerr
Published 2020-09-01

Human Cytomegalovirus Infection Upregulates the Mitochondrial Transcription and Translation Machineries

by S. Karniely, M. P. Weekes, R. Antrobus, J. Rorbach, L. van Haute, Y. Umrania, D. L. Smith, R. J. Stanton, M. Minczuk, P. J. Lehner, J. H. Sinclair
Published 2016-03-01