Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly dividing de‐differentiated state

by Becker, Verena, Izar, Benjamin, Baker, Gregory J, Lin, Jia?Ren, Boswell, Sarah A, Shah, Parin, Rotem, Asaf, Sorger, Peter K, Fallahi-Sichani, Mohammad, Garraway, Levi
Published 2017

Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma

by Liu, David V., Liu, Derek, Jerby-Arnon, Livnat, Vokes, Natalie I., Margolis, Claire A., Conway, Jake, He, Meng Xiao, Elmarakeby, Haitham, Dietlein, Felix, Miao, Diana, Tracy, Adam, Izar, Benjamin, Regev, Aviv, Van Allen, Eliezer M.
Published 2020

IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment

by Nirschl, Christopher J., Suárez-Fariñas, Mayte, Izar, Benjamin, Dannenfelser, Ruth, Tirosh, Itay, Liu, Yong, Zhu, Qian, Devi, K. Sanjana P., Chau, David, Rezaee, Melika, Kim, Tae-Gyun, Huang, Ruiqi, Fuentes-Duculan, Judilyn, Song-Zhao, George X., Gulati, Nicholas, Lowes, Michelle A., King, Sandra L., Quintana, Francisco J., Lee, Young-suk, Krueger, James G., Sarin, Kavita Y., Yoon, Charles H., Troyanskaya, Olga, Anandasabapathy, Niroshana, Prakadan, Sanjay, Carroll, Shaina Laufer, Regev, Aviv, Shalek, Alexander K, Garraway, Levi A.
Published 2018

Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma

by Tirosh, Itay, Venteicher, Andrew S., Hebert, Christine, Escalante, Leah E., Patel, Anoop P., Yizhak, Keren, Fisher, Jonathan M., Rodman, Christopher, Mount, Christopher, Filbin, Mariella G., Neftel, Cyril, Desai, Niyati, Nyman, Jackson, Izar, Benjamin, Luo, Christina C., Francis, Joshua M., Patel, Aanand A., Onozato, Maristela L., Riggi, Nicolo, Livak, Kenneth J., Gennert, Dave, Satija, Rahul, Nahed, Brian V., Curry, William T., Martuza, Robert L., Mylvaganam, Ravindra, Iafrate, A. John, Frosch, Matthew P., Rivera, Miguel N., Getz, Gad, Rozenblatt-Rosen, Orit, Cahill, Daniel P., Monje, Michelle, Bernstein, Bradley E., Louis, David N., Suvà, Mario L., Golub, Todd, Regev, Aviv
Published 2018

A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade

by Jerby-Arnon, Livnat, Shah, Parin, Cuoco, Michael S., Rodman, Christopher, Su, Mei-Ju, Melms, Johannes C., Leeson, Rachel, Kanodia, Abhay, Mei, Shaolin, Lin, Jia-Ren, Wang, Shu, Rabasha, Bokang, Liu, David, Zhang, Gao, Margolais, Claire, Ashenberg, Orr, Ott, Patrick A., Buchbinder, Elizabeth I., Haq, Rizwan, Hodi, F. Stephen, Boland, Genevieve M., Sullivan, Ryan J., Frederick, Dennie T., Miao, Benchun, Moll, Tabea, Flaherty, Keith T., Herlyn, Meenhard, Jenkins, Russell W., Thummalapalli, Rohit, Kowalczyk, Monika S., Cañadas, Israel, Schilling, Bastian, Cartwright, Adam N.R, Luoma, Adrienne M., Malu, Shruti, Hwu, Patrick, Bernatchez, Chantale, Forget, Marie-Andrée, Barbie, David A., Shalek, Alex K., Tirosh, Itay, Sorger, Peter K., Wucherpfennig, Kai, Van Allen, Eliezer M., Schadendorf, Dirk, Johnson, Bruce E., Rotem, Asaf, Rozenblatt-Rosen, Orit, Garraway, Levi A., Yoon, Charles H., Izar, Benjamin, Regev, Aviv
Published 2020