Activation of protein tyrosine phosphatase non-receptor type 2 by spermidine exerts anti-inflammatory effects in human THP-1 monocytes and in a mouse model of acute colitis.

by Belén Morón, Marianne Spalinger, Stephanie Kasper, Kirstin Atrott, Isabelle Frey-Wagner, Michael Fried, Declan F McCole, Gerhard Rogler, Michael Scharl
Published 2013-01-01

Regulation of the expression of chaperone gp96 in macrophages and dendritic cells.

by Lutz Wolfram, Anne Fischbeck, Isabelle Frey-Wagner, Kacper A Wojtal, Silvia Lang, Michael Fried, Stephan R Vavricka, Martin Hausmann, Gerhard Rogler
Published 2013-01-01

Genotype–phenotype associations of polymorphisms within the gene locus of NOD-like receptor pyrin domain containing 3 in Swiss inflammatory bowel disease patients

by Priyatharsan Yoganathan, Jean-Benoit Rossel, Sebastian Bruno Ulrich Jordi, Yannick Franc, Luc Biedermann, Benjamin Misselwitz, Martin Hausmann, Gerhard Rogler, Michael Scharl, Isabelle Frey-Wagner, Swiss IBD cohort study group
Published 2021-08-01

Gp96 deficiency affects TLR4 functionality and impairs ERK and p38 phosphorylation.

by Jesus Cosin-Roger, Marianne R Spalinger, Pedro A Ruiz, Claudia Stanzel, Anne Terhalle, Lutz Wolfram, Hassan Melhem, Kirstin Atrott, Silvia Lang, Isabelle Frey-Wagner, Michael Fried, Michael Scharl, Martin Hausmann, Gerhard Rogler
Published 2018-01-01

Hypoxia ameliorates intestinal inflammation through NLRP3/mTOR downregulation and autophagy activation

by Jesus Cosin-Roger, Simona Simmen, Hassan Melhem, Kirstin Atrott, Isabelle Frey-Wagner, Martin Hausmann, Cheryl de Vallière, Marianne R. Spalinger, Patrick Spielmann, Roland H. Wenger, Jonas Zeitz, Stephan R. Vavricka, Gerhard Rogler, Pedro A. Ruiz
Published 2017-07-01

Hypoxia Reduces the Transcription of Fibrotic Markers in the Intestinal Mucosa

by Simona Simmen, Max Maane, Sarah Rogler, Katherina Baebler, Silvia Lang, Jesus Cosin-Roger, Kirstin Atrott, Isabelle Frey-Wagner, Partick Spielmann, Roland H. Wenger, Bruce Weder, Jonas Zeitz, Stephan R. Vavricka, Gerhard Rogler, Cheryl de Vallière, Martin Hausmann, Pedro A. Ruiz
Published 2021-03-01

Elevated oxysterol levels in human and mouse livers reflect nonalcoholic steatohepatitis[S]

by Tina Raselli, Tom Hearn, Annika Wyss, Kirstin Atrott, Alain Peter, Isabelle Frey-Wagner, Marianne R. Spalinger, Ewerton M. Maggio, Andreas W. Sailer, Johannes Schmitt, Philipp Schreiner, Anja Moncsek, Joachim Mertens, Michael Scharl, William J. Griffiths, Marco Bueter, Andreas Geier, Gerhard Rogler, Yuqin Wang, Benjamin Misselwitz
Published 2019-07-01