Low dose ionizing radiation strongly stimulates insertional mutagenesis in a γH2AX dependent manner.

by Alex N Zelensky, Mascha Schoonakker, Inger Brandsma, Marcel Tijsterman, Dik C van Gent, Jeroen Essers, Roland Kanaar
Published 2020-01-01

On the Mechanism of Hyperthermia-Induced BRCA2 Protein Degradation

by Nathalie van den Tempel, Alex N. Zelensky, Hanny Odijk, Charlie Laffeber, Christine K. Schmidt, Inger Brandsma, Jeroen Demmers, Przemek M. Krawczyk, Roland Kanaar
Published 2019-01-01

Attenuated XPC expression is not associated with impaired DNA repair in bladder cancer.

by Kishan A T Naipal, Anja Raams, Serena T Bruens, Inger Brandsma, Nicole S Verkaik, Nicolaas G J Jaspers, Jan H J Hoeijmakers, Geert J L H van Leenders, Joris Pothof, Roland Kanaar, Joost Boormans, Dik C van Gent
Published 2015-01-01

Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance

by Stephen J. Pettitt, Dragomir B. Krastev, Inger Brandsma, Amy Dréan, Feifei Song, Radoslav Aleksandrov, Maria I. Harrell, Malini Menon, Rachel Brough, James Campbell, Jessica Frankum, Michael Ranes, Helen N. Pemberton, Rumana Rafiq, Kerry Fenwick, Amanda Swain, Sebastian Guettler, Jung-Min Lee, Elizabeth M. Swisher, Stoyno Stoynov, Kosuke Yusa, Alan Ashworth, Christopher J. Lord
Published 2018-05-01

HSF2BP Interacts with a Conserved Domain of BRCA2 and Is Required for Mouse Spermatogenesis

by Inger Brandsma, Koichi Sato, Sari E. van Rossum-Fikkert, Nicole van Vliet, Esther Sleddens, Marcel Reuter, Hanny Odijk, Nathalie van den Tempel, Dick H.W. Dekkers, Karel Bezstarosti, Jeroen A.A. Demmers, Alex Maas, Joyce Lebbink, Claire Wyman, Jeroen Essers, Dik C. van Gent, Willy M. Baarends, Puck Knipscheer, Roland Kanaar, Alex N. Zelensky
Published 2019-06-01