Dual-functional peptide with defective interfering genes effectively protects mice against avian and seasonal influenza

by Hanjun Zhao, Kelvin K. W. To, Hin Chu, Qiulu Ding, Xiaoyu Zhao, Cun Li, Huiping Shuai, Shuofeng Yuan, Jie Zhou, Kin-Hang Kok, Shibo Jiang, Kwok-Yung Yuen
Published 2018-06-01

Characterization of the Lipidomic Profile of Human Coronavirus-Infected Cells: Implications for Lipid Metabolism Remodeling upon Coronavirus Replication

by Bingpeng Yan, Hin Chu, Dong Yang, Kong-Hung Sze, Pok-Man Lai, Shuofeng Yuan, Huiping Shuai, Yixin Wang, Richard Yi-Tsun Kao, Jasper Fuk-Woo Chan, Kwok-Yung Yuen
Published 2019-01-01

SARS-CoV-2 Induces a More Robust Innate Immune Response and Replicates Less Efficiently Than SARS-CoV in the Human Intestines: An Ex Vivo Study With Implications on Pathogenesis of...

by Hin Chu, Jasper Fuk-Woo Chan, Yixin Wang, Terrence Tsz-Tai Yuen, Yue Chai, Huiping Shuai, Dong Yang, Bingjie Hu, Xiner Huang, Xi Zhang, Yuxin Hou, Jian-Piao Cai, Anna Jinxia Zhang, Jie Zhou, Shuofeng Yuan, Kelvin Kai-Wang To, Ivan Fan-Ngai Hung, Tan To Cheung, Ada Tsui-Lin Ng, Ivy Hau-Yee Chan, Ian Yu-Hong Wong, Simon Ying-Kit Law, Dominic Chi-Chung Foo, Wai-Keung Leung, Kwok-Yung Yuen
Published 2021-01-01

Host and viral determinants for efficient SARS-CoV-2 infection of the human lung

by Hin Chu, Bingjie Hu, Xiner Huang, Yue Chai, Dongyan Zhou, Yixin Wang, Huiping Shuai, Dong Yang, Yuxin Hou, Xi Zhang, Terrence Tsz-Tai Yuen, Jian-Piao Cai, Anna Jinxia Zhang, Jie Zhou, Shuofeng Yuan, Kelvin Kai-Wang To, Ivy Hau-Yee Chan, Ko-Yung Sit, Dominic Chi-Chung Foo, Ian Yu-Hong Wong, Ada Tsui-Lin Ng, Tan To Cheung, Simon Ying-Kit Law, Wing-Kuk Au, Melinda A. Brindley, Zhiwei Chen, Kin-Hang Kok, Jasper Fuk-Woo Chan, Kwok-Yung Yuen
Published 2021-01-01

Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory stud...

by Hin Chu, PhD, Jasper Fuk-Woo Chan, MD, Terrence Tsz-Tai Yuen, BA, Huiping Shuai, PhD, Shuofeng Yuan, PhD, Yixin Wang, MPhil, Bingjie Hu, MPhil, Cyril Chik-Yan Yip, PhD, Jessica Oi-Ling Tsang, BSc, Xiner Huang, BSc, Yue Chai, MPhil, Dong Yang, MPhil, Yuxin Hou, MPhil, Kenn Ka-Heng Chik, MMedSc, Xi Zhang, BSc, Agnes Yim-Fong Fung, BSc, Hoi-Wah Tsoi, MPhil, Jian-Piao Cai, BSc, Wan-Mui Chan, PhD, Jonathan Daniel Ip, MSc, Allen Wing-Ho Chu, MSc, Jie Zhou, PhD, David Christopher Lung, FRCPath, Kin-Hang Kok, PhD, Kelvin Kai-Wang To, MD, Owen Tak-Yin Tsang, FRCP, Kwok-Hung Chan, PhD, Kwok-Yung Yuen, ProfMD
Published 2020-05-01