Acetate metabolism in cancer cells

by Hosios, Aaron M, Vander Heiden, Matthew G.
Published 2014

Cancer‐associated mutations in human pyruvate kinase M2 impair enzyme activity

by Liu, Vivian M., Howell, Andrea J., Hosios, Aaron M., Li, Zhaoqi, Israelsen, William J., Vander Heiden, Matthew G.
Published 2022

Cancer‐associated mutations in human pyruvate kinase M2 impair enzyme activity

by Liu, Vivian M., Howell, Andrea J., Hosios, Aaron M., Li, Zhaoqi, Israelsen, William J., Vander Heiden, Matthew G.
Published 2022

Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer

by Luengo, Alba, Abbott, Keene L., Davidson, Shawn M., Hosios, Aaron M., Chan, Sze Ham, Freinkman, Elizaveta, Lewis, Caroline A., Vander Heiden, Matthew G.
Published 2020

Aspartate is an endogenous metabolic limitation for tumour growth

by Sullivan, Lucas B., Luengo, Alba, Danai, Laura V., Bush, Lauren N., Diehl, Frances F., Hosios, Aaron M., Lau, Allison N., Elmiligy, Sarah, Lewis, Caroline A., Vander Heiden, Matthew G.
Published 2020

Differential substrate use in EGF‐ and oncogenic KRAS‐stimulated human mammary epithelial cells

by Keibler, Mark A., Dong, Wentao, Korthauer, Keegan D., Hosios, Aaron M., Moon, Sun Jin, Sullivan, Lucas B., Liu, Nian, Abbott, Keene L., Arevalo, Orlando D., Ho, Kailing, Lee, Jennifer, Phanse, Aasavari S., Kelleher, Joanne K., Iliopoulos, Othon, Coloff, Jonathan L., Vander Heiden, Matthew G., Stephanopoulos, Gregory
Published 2022

Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth

by Cox, Andrew G, Tsomides, Allison, Yimlamai, Dean, Hwang, Katie L, Miesfeld, Joel, Galli, Giorgio G, Fowl, Brendan H, Fort, Michael, Ma, Kimberly Y, Sullivan, Mark R, Hosios, Aaron M, Snay, Erin, Yuan, Min, Brown, Kristin K, Lien, Evan C, Chhangawala, Sagar, Steinhauser, Matthew L, Asara, John M, Houvras, Yariv, Link, Brian, Vander Heiden, Matthew G, Camargo, Fernando D, Goessling, Wolfram
Published 2020