Intracellular alkalinization induces cytosolic Ca2+ increases by inhibiting sarco/endoplasmic reticulum Ca2+-ATPase (SERCA).

by Sen Li, Baixia Hao, Yingying Lu, Peilin Yu, Hon-Cheung Lee, Jianbo Yue
Published 2012-01-01

A cell permeable NPE caged ADP-ribose for studying TRPM2.

by Peilin Yu, Qian Wang, Li-He Zhang, Hon-Cheung Lee, Liangren Zhang, Jianbo Yue
Published 2012-01-01

Design, Synthesis and SAR Studies of NAD Analogues as Potent Inhibitors towards CD38 NADase

by Shengjun Wang, Wenjie Zhu, Xuan Wang, Jianguo Li, Kehui Zhang, Liangren Zhang, Yong-Juan Zhao, Hon Cheung Lee, Lihe Zhang
Published 2014-09-01

CD38 Structure-Based Inhibitor Design Using the N1-Cyclic Inosine 5'-Diphosphate Ribose Template.

by Christelle Moreau, Qun Liu, Richard Graeff, Gerd K Wagner, Mark P Thomas, Joanna M Swarbrick, Satoshi Shuto, Hon Cheung Lee, Quan Hao, Barry V L Potter
Published 2013-01-01

A Cell-Permeant Mimetic of NMN Activates SARM1 to Produce Cyclic ADP-Ribose and Induce Non-apoptotic Cell Death

by Zhi Ying Zhao, Xu Jie Xie, Wan Hua Li, Jun Liu, Zhe Chen, Ben Zhang, Ting Li, Song Lu Li, Jun Gang Lu, Liangren Zhang, Li-he Zhang, Zhengshuang Xu, Hon Cheung Lee, Yong Juan Zhao
Published 2019-05-01

Permeant fluorescent probes visualize the activation of SARM1 and uncover an anti-neurodegenerative drug candidate

by Wan Hua Li, Ke Huang, Yang Cai, Qian Wen Wang, Wen Jie Zhu, Yun Nan Hou, Sujing Wang, Sheng Cao, Zhi Ying Zhao, Xu Jie Xie, Yang Du, Chi-Sing Lee, Hon Cheung Lee, Hongmin Zhang, Yong Juan Zhao
Published 2021-05-01

Cyclic ADP-ribose and heat regulate oxytocin release via CD38 and TRPM2 in the hypothalamus during social or psychological stress in mice

by Jing Zhong, Sarwat Amina, Mingkun Liang, Shirin Akther, Teruko Yuhi, Tomoko Nishimura, Chiharu Higashida, Takahiro Tsuji, Hong-Xiang Liu, Minako Hashii, Kazumi Furuhara, Shigeru Yokoyama, Yasuhiko Yamamoto, Hiroshi Okamoto, Yong Juan Zhao, Hon Cheung Lee, Makoto Tominaga, Olga Lopatina, Haruhiro Higashida
Published 2016-07-01