Design, Synthesis and SAR Studies of NAD Analogues as Potent Inhibitors towards CD38 NADase

by Shengjun Wang, Wenjie Zhu, Xuan Wang, Jianguo Li, Kehui Zhang, Liangren Zhang, Yong-Juan Zhao, Hon Cheung Lee, Lihe Zhang
Published 2014-09-01

The mitigation effects of exogenous dopamine on low nitrogen stress in Malus hupehensis

by Xiao-min LIU, Teng-teng GAO, Zhi-jun ZHANG, Ke-xin TAN, Yi-bo JIN, Yong-juan ZHAO, Feng-wang MA, Chao LI
Published 2020-11-01

The complex structure of GRL0617 and SARS-CoV-2 PLpro reveals a hot spot for antiviral drug discovery

by Ziyang Fu, Bin Huang, Jinle Tang, Shuyan Liu, Ming Liu, Yuxin Ye, Zhihong Liu, Yuxian Xiong, Wenning Zhu, Dan Cao, Jihui Li, Xiaogang Niu, Huan Zhou, Yong Juan Zhao, Guoliang Zhang, Hao Huang
Published 2021-01-01

A Cell-Permeant Mimetic of NMN Activates SARM1 to Produce Cyclic ADP-Ribose and Induce Non-apoptotic Cell Death

by Zhi Ying Zhao, Xu Jie Xie, Wan Hua Li, Jun Liu, Zhe Chen, Ben Zhang, Ting Li, Song Lu Li, Jun Gang Lu, Liangren Zhang, Li-he Zhang, Zhengshuang Xu, Hon Cheung Lee, Yong Juan Zhao
Published 2019-05-01

Direct Gating of the TRPM2 Channel by cADPR via Specific Interactions with the ADPR Binding Pocket

by Peilin Yu, Zhenming Liu, Xiafei Yu, Peiwu Ye, Huan Liu, Xiwen Xue, Lixin Yang, Zhongtang Li, Yang Wu, Cheng Fang, Yong Juan Zhao, Fan Yang, Jian Hong Luo, Lin-Hua Jiang, Liangren Zhang, Lihe Zhang, Wei Yang
Published 2019-06-01

Permeant fluorescent probes visualize the activation of SARM1 and uncover an anti-neurodegenerative drug candidate

by Wan Hua Li, Ke Huang, Yang Cai, Qian Wen Wang, Wen Jie Zhu, Yun Nan Hou, Sujing Wang, Sheng Cao, Zhi Ying Zhao, Xu Jie Xie, Yang Du, Chi-Sing Lee, Hon Cheung Lee, Hongmin Zhang, Yong Juan Zhao
Published 2021-05-01

Cyclic ADP-ribose and heat regulate oxytocin release via CD38 and TRPM2 in the hypothalamus during social or psychological stress in mice

by Jing Zhong, Sarwat Amina, Mingkun Liang, Shirin Akther, Teruko Yuhi, Tomoko Nishimura, Chiharu Higashida, Takahiro Tsuji, Hong-Xiang Liu, Minako Hashii, Kazumi Furuhara, Shigeru Yokoyama, Yasuhiko Yamamoto, Hiroshi Okamoto, Yong Juan Zhao, Hon Cheung Lee, Makoto Tominaga, Olga Lopatina, Haruhiro Higashida
Published 2016-07-01