Tumor cell death by pattern-sensing of exogenous RNA: Tumor cell TLR3 directly induces necroptosis by poly(I:C) in vivo, independent of immune effector-mediated tumor shrinkage

by Hiromi Takaki, Hiroaki Shime, Misako Matsumoto, Tsukasa Seya
Published 2017-10-01

RIOK3-Mediated Phosphorylation of MDA5 Interferes with Its Assembly and Attenuates the Innate Immune Response

by Ken Takashima, Hiroyuki Oshiumi, Hiromi Takaki, Misako Matsumoto, Tsukasa Seya
Published 2015-04-01

The Anti-Oxidant Ergothioneine Augments the Immunomodulatory Function of TLR Agonists by Direct Action on Macrophages.

by Sumito Yoshida, Hiroaki Shime, Kenji Funami, Hiromi Takaki, Misako Matsumoto, Masanori Kasahara, Tsukasa Seya
Published 2017-01-01

cGAMP Promotes Germinal Center Formation and Production of IgA in Nasal-Associated Lymphoid Tissue

by Hiromi Takaki, Ken Takashima, Hiroyuki Oshiumi, Akira Ainai, Tadaki Suzuki, Hideki Hasegawa, Misako Matsumoto, Tsukasa Seya
Published 2017-12-01

The TLR3/TICAM-1 signal constitutively controls spontaneous polyposis through suppression of c-Myc in Apc Min/+ mice

by Junya Ono, Hiroaki Shime, Hiromi Takaki, Ken Takashima, Kenji Funami, Sumito Yoshida, Yohei Takeda, Misako Matsumoto, Masanori Kasahara, Tsukasa Seya
Published 2017-10-01

Activated circulating T follicular helper cells and skewing of T follicular helper 2 cells are down-regulated by treatment including an inhaled corticosteroid in patients with alle...

by Satsuki Miyajima, Katsunori Shigehara, Ryuta Kamekura, Hiromi Takaki, Hayato Yabe, Ippei Ikegami, Yuichiro Asai, Hirotaka Nishikiori, Hirohumi Chiba, Eiji Uno, Hiroki Takahashi, Shingo Ichimiya
Published 2020-01-01