p62‐mediated autophagy affects nutrition‐dependent insulin receptor substrate 1 dynamics in 3T3‐L1 preadipocytes

by Hirobumi Igawa, Akihiro Kikuchi, Hirofumi Misu, Kiyo‐aki Ishii, Shuichi Kaneko, Toshinari Takamura
Published 2019-01-01

Concentration-dependent dual effects of hydrogen peroxide on insulin signal transduction in H4IIEC hepatocytes.

by Satoshi Iwakami, Hirofumi Misu, Takashi Takeda, Makoto Sugimori, Seiichi Matsugo, Shuichi Kaneko, Toshinari Takamura
Published 2011-01-01

Effects of metformin and alogliptin on body composition in people with type 2 diabetes

by Yumie Takeshita, Yuki Kita, Ken‐ichiro Kato, Takehiro Kanamori, Hirofumi Misu, Shuichi Kaneko, Toshinari Takamura
Published 2019-05-01

Inverse correlation between serum levels of selenoprotein P and adiponectin in patients with type 2 diabetes.

by Hirofumi Misu, Kazuhide Ishikura, Seiichiro Kurita, Yumie Takeshita, Tsuguhito Ota, Yoshiro Saito, Kazuhiko Takahashi, Shuichi Kaneko, Toshinari Takamura
Published 2012-01-01

Inhibin βE (INHBE) is a possible insulin resistance-associated hepatokine identified by comprehensive gene expression analysis in human liver biopsy samples.

by Masakazu Sugiyama, Akihiro Kikuchi, Hirofumi Misu, Hirobumi Igawa, Motooki Ashihara, Youichi Kushima, Kiyofumi Honda, Yoshiyuki Suzuki, Yoshiki Kawabe, Shuichi Kaneko, Toshinari Takamura
Published 2018-01-01

Ectopic fat accumulation and distant organ-specific insulin resistance in Japanese people with nonalcoholic fatty liver disease.

by Ken-ichiro Kato, Toshinari Takamura, Yumie Takeshita, Yasuji Ryu, Hirofumi Misu, Tsuguhito Ota, Kumpei Tokuyama, Shoichiro Nagasaka, Munehide Matsuhisa, Osamu Matsui, Shuichi Kaneko
Published 2014-01-01

Endogenous Selenoprotein P, a Liver-Derived Secretory Protein, Mediates Myocardial Ischemia/Reperfusion Injury in Mice

by Hiroshi Chadani, Soichiro Usui, Oto Inoue, Takashi Kusayama, Shin-ichiro Takashima, Takeshi Kato, Hisayoshi Murai, Hiroshi Furusho, Ayano Nomura, Hirofumi Misu, Toshinari Takamura, Shuichi Kaneko, Masayuki Takamura
Published 2018-03-01

Selenoprotein P-neutralizing antibodies improve insulin secretion and glucose sensitivity in type 2 diabetes mouse models

by Yuichiro Mita, Kaho Nakayama, Shogo Inari, Yukina Nishito, Yuya Yoshioka, Naoko Sakai, Kanade Sotani, Takahiro Nagamura, Yuki Kuzuhara, Kumi Inagaki, Miki Iwasaki, Hirofumi Misu, Masaya Ikegawa, Toshinari Takamura, Noriko Noguchi, Yoshiro Saito
Published 2017-11-01

Metformin prevents and reverses inflammation in a non-diabetic mouse model of nonalcoholic steatohepatitis.

by Yuki Kita, Toshinari Takamura, Hirofumi Misu, Tsuguhito Ota, Seiichiro Kurita, Yumie Takeshita, Masafumi Uno, Naoto Matsuzawa-Nagata, Ken-Ichiro Kato, Hitoshi Ando, Akio Fujimura, Koji Hayashi, Toru Kimura, Yinhua Ni, Toshiki Otoda, Ken-ichi Miyamoto, Yoh Zen, Yasuni Nakanuma, Shuichi Kaneko
Published 2012-01-01