Antioxidants Improve the Phenotypes of Dilated Cardiomyopathy and Muscle Fatigue in Mitochondrial Superoxide Dismutase-Deficient Mice

by Takahiko Shimizu, Takuji Shirasawa, Tadahiro Sunagawa, Satoru Kawakami, Hirofumi Koyama, Hidetoshi Nojiri
Published 2013-01-01

Sod1 Loss Induces Intrinsic Superoxide Accumulation Leading to p53-Mediated Growth Arrest and Apoptosis

by Kenji Watanabe, Shuichi Shibuya, Hirofumi Koyama, Yusuke Ozawa, Toshihiko Toda, Koutaro Yokote, Takahiko Shimizu
Published 2013-05-01

Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture.

by Akira Shimamoto, Harunobu Kagawa, Kazumasa Zensho, Yukihiro Sera, Yasuhiro Kazuki, Mitsuhiko Osaki, Mitsuo Oshimura, Yasuhito Ishigaki, Kanya Hamasaki, Yoshiaki Kodama, Shinsuke Yuasa, Keiichi Fukuda, Kyotaro Hirashima, Hiroyuki Seimiya, Hirofumi Koyama, Takahiko Shimizu, Minoru Takemoto, Koutaro Yokote, Makoto Goto, Hidetoshi Tahara
Published 2014-01-01