Towards Bioengineered Liver Stem Cell Transplantation Studies in a Preclinical Dog Model for Inherited Copper Toxicosis

by Hedwig S. Kruitwagen, Hille Fieten, Louis C. Penning
Published 2019-09-01

Translation From Mice to Men: Are Dogs a Dodgy Intermediate?

by Hedwig S. Kruitwagen, Bart Spee, Hille Fieten, Frank G. van Steenbeek, Baukje A. Schotanus, Louis C. Penning
Published 2014-05-01

Reduced FXR Target Gene Expression in Copper-Laden Livers of COMMD1-Deficient Dogs

by Xiaoyan Wu, Hsiaotzu Chien, Monique E. van Wolferen, Hedwig S. Kruitwagen, Loes A. Oosterhoff, Louis C. Penning
Published 2019-09-01

Intestinal Organoids—Current and Future Applications

by Andre M. C. Meneses, Kerstin Schneeberger, Hedwig S. Kruitwagen, Louis C. Penning, Frank G. van Steenbeek, Iwan A. Burgener, Bart Spee
Published 2016-10-01

Innovative application of an implantable venous access system in the portal vein: technique, results and complications in three dogs

by Kiona S. de Nies, Hedwig S. Kruitwagen, Giora van Straten, Leonie W. L. van Bruggen, Joris H. Robben, Baukje A. Schotanus, Ies Akkerdaas, Anne Kummeling
Published 2019-07-01

Identification of potential drugs for treatment of hepatic lipidosis in cats using an in vitro feline liver organoid system

by Maya W. Haaker, Hedwig S. Kruitwagen, Arie B. Vaandrager, Martin Houweling, Louis C. Penning, Martijn R. Molenaar, Monique E. vanWolferen, Loes A. Oosterhoff, Bart Spee, J. Bernd Helms
Published 2020-01-01

Generation of Differentiating and Long-Living Intestinal Organoids Reflecting the Cellular Diversity of Canine Intestine

by Nina Kramer, Barbara Pratscher, Andre M. C. Meneses, Waltraud Tschulenk, Ingrid Walter, Alexander Swoboda, Hedwig S. Kruitwagen, Kerstin Schneeberger, Louis C. Penning, Bart Spee, Matthias Kieslinger, Sabine Brandt, Iwan A. Burgener
Published 2020-03-01

Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids

by Sathidpak Nantasanti, Bart Spee, Hedwig S. Kruitwagen, Chen Chen, Niels Geijsen, Loes A. Oosterhoff, Monique E. van Wolferen, Nicolas Pelaez, Hille Fieten, Richard W. Wubbolts, Guy C. Grinwis, Jefferson Chan, Meritxell Huch, Robert R.G. Vries, Hans Clevers, Alain de Bruin, Jan Rothuizen, Louis C. Penning, Baukje A. Schotanus
Published 2015-11-01

Aberrant hepatic lipid storage and metabolism in canine portosystemic shunts.

by Lindsay Van den Bossche, Vivien A C Schoonenberg, Iwan A Burgener, Louis C Penning, Ingrid M Schrall, Hedwig S Kruitwagen, Monique E van Wolferen, Guy C M Grinwis, Anne Kummeling, Jan Rothuizen, Jeroen F van Velzen, Nikolas Stathonikos, Martijn R Molenaar, Bernd J Helms, Jos F H M Brouwers, Bart Spee, Frank G van Steenbeek
Published 2017-01-01

Characterization of Endothelial and Smooth Muscle Cells From Different Canine Vessels

by Loes A. Oosterhoff, Hedwig S. Kruitwagen, Monique E. van Wolferen, Bas W.M. van Balkom, Michal Mokry, Michal Mokry, Nico Lansu, Nico Lansu, Noortje A.M. van den Dungen, Noortje A.M. van den Dungen, Louis C. Penning, Talitha C.F. Spanjersberg, Johannes W. de Graaf, Tomas Veenendaal, Flin Zomerdijk, Joost O. Fledderus, Bart Spee, Frank G. van Steenbeek
Published 2019-02-01

Long-Term Adult Feline Liver Organoid Cultures for Disease Modeling of Hepatic Steatosis

by Hedwig S. Kruitwagen, Loes A. Oosterhoff, Ingrid G.W.H. Vernooij, Ingrid M. Schrall, Monique E. van Wolferen, Farah Bannink, Camille Roesch, Lisa van Uden, Martijn R. Molenaar, J. Bernd Helms, Guy C.M. Grinwis, Monique M.A. Verstegen, Luc J.W. van der Laan, Meritxell Huch, Niels Geijsen, Robert G. Vries, Hans Clevers, Jan Rothuizen, Baukje A. Schotanus, Louis C. Penning, Bart Spee
Published 2017-04-01

Long-Term Survival of Transplanted Autologous Canine Liver Organoids in a <i>COMMD1</i>-Deficient Dog Model of Metabolic Liver Disease

by Hedwig S. Kruitwagen, Loes A. Oosterhoff, Monique E. van Wolferen, Chen Chen, Sathidpak Nantasanti Assawarachan, Kerstin Schneeberger, Anne Kummeling, Giora van Straten, Ies C. Akkerdaas, Christel R. Vinke, Frank G. van Steenbeek, Leonie W.L. van Bruggen, Jeannette Wolfswinkel, Guy C.M. Grinwis, Sabine A. Fuchs, Helmuth Gehart, Niels Geijsen, Robert G. Vries, Hans Clevers, Jan Rothuizen, Baukje A. Schotanus, Louis C. Penning, Bart Spee
Published 2020-02-01