Transcriptome association studies of neuropsychiatric traits in African Americans implicate PRMT7 in schizophrenia

by Peter N. Fiorica, Heather E. Wheeler
Published 2019-09-01

Genetically regulated gene expression underlies lipid traits in Hispanic cohorts.

by Angela Andaleon, Lauren S Mogil, Heather E Wheeler
Published 2019-01-01

Population-Matched Transcriptome Prediction Increases TWAS Discovery and Replication Rate

by Elyse Geoffroy, Isabelle Gregga, Heather E. Wheeler
Published 2020-12-01

Comparing local ancestry inference models in populations of two- and three-way admixture

by Ryan Schubert, Angela Andaleon, Heather E. Wheeler
Published 2020-10-01

Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels

by Angela Andaleon, Lauren S. Mogil, Heather E. Wheeler
Published 2018-01-01

Modeling chemotherapeutic neurotoxicity with human induced pluripotent stem cell-derived neuronal cells.

by Heather E Wheeler, Claudia Wing, Shannon M Delaney, Masaaki Komatsu, M Eileen Dolan
Published 2015-01-01

Multi-ethnic transcriptome-wide association study of prostate cancer.

by Peter N Fiorica, Ryan Schubert, John D Morris, Mohammed Abdul Sami, Heather E Wheeler
Published 2020-01-01

Application of stem cell derived neuronal cells to evaluate neurotoxic chemotherapy

by Claudia Wing, Masaaki Komatsu, Shannon M. Delaney, Matthew Krause, Heather E. Wheeler, M. Eileen Dolan
Published 2017-07-01

Integrating predicted transcriptome from multiple tissues improves association detection.

by Alvaro N Barbeira, Milton Pividori, Jiamao Zheng, Heather E Wheeler, Dan L Nicolae, Hae Kyung Im
Published 2019-01-01

EPS8 inhibition increases cisplatin sensitivity in lung cancer cells.

by Lidija K Gorsic, Amy L Stark, Heather E Wheeler, Shan S Wong, Hae K Im, M Eileen Dolan
Published 2013-01-01

Genome-wide local ancestry approach identifies genes and variants associated with chemotherapeutic susceptibility in African Americans.

by Heather E Wheeler, Lidija K Gorsic, Marleen Welsh, Amy L Stark, Eric R Gamazon, Nancy J Cox, M Eileen Dolan
Published 2011-01-01

Chronic circadian misalignment results in reduced longevity and large-scale changes in gene expression in Drosophila

by Alex C. Boomgarden, Gabriel D. Sagewalker, Aashaka C. Shah, Sarah D. Haider, Pramathini Patel, Heather E. Wheeler, Christine M. Dubowy, Daniel J. Cavanaugh
Published 2019-01-01

Survey of the Heritability and Sparse Architecture of Gene Expression Traits across Human Tissues.

by Heather E Wheeler, Kaanan P Shah, Jonathon Brenner, Tzintzuni Garcia, Keston Aquino-Michaels, GTEx Consortium, Nancy J Cox, Dan L Nicolae, Hae Kyung Im
Published 2016-11-01

Genetic architecture of gene expression traits across diverse populations.

by Lauren S Mogil, Angela Andaleon, Alexa Badalamenti, Scott P Dickinson, Xiuqing Guo, Jerome I Rotter, W Craig Johnson, Hae Kyung Im, Yongmei Liu, Heather E Wheeler
Published 2018-08-01

Transcriptome prediction performance across machine learning models and diverse ancestries

by Paul C. Okoro, Ryan Schubert, Xiuqing Guo, W. Craig Johnson, Jerome I. Rotter, Ina Hoeschele, Yongmei Liu, Hae Kyung Im, Amy Luke, Lara R. Dugas, Heather E. Wheeler
Published 2021-04-01

Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.

by Heather E Wheeler, E Jeffrey Metter, Toshiko Tanaka, Devin Absher, John Higgins, Jacob M Zahn, Julie Wilhelmy, Ronald W Davis, Andrew Singleton, Richard M Myers, Luigi Ferrucci, Stuart K Kim
Published 2009-10-01

Genetic Variants Contributing to Colistin Cytotoxicity: Identification of TGIF1 and HOXD10 Using a Population Genomics Approach

by Michael T. Eadon, Ronald J. Hause, Amy L. Stark, Ying-Hua Cheng, Heather E. Wheeler, Kimberly S. Burgess, Eric A. Benson, Patrick N. Cunningham, Robert L. Bacallao, Pierre C. Dagher, Todd C. Skaar, M. Eileen Dolan
Published 2017-03-01

Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics

by Alvaro N. Barbeira, Scott P. Dickinson, Rodrigo Bonazzola, Jiamao Zheng, Heather E. Wheeler, Jason M. Torres, Eric S. Torstenson, Kaanan P. Shah, Tzintzuni Garcia, Todd L. Edwards, Eli A. Stahl, Laura M. Huckins, GTEx Consortium, Dan L. Nicolae, Nancy J. Cox, Hae Kyung Im
Published 2018-05-01

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function

by Annah B. Wyss, Tamar Sofer, Mi Kyeong Lee, Natalie Terzikhan, Jennifer N. Nguyen, Lies Lahousse, Jeanne C. Latourelle, Albert Vernon Smith, Traci M. Bartz, Mary F. Feitosa, Wei Gao, Tarunveer S. Ahluwalia, Wenbo Tang, Christopher Oldmeadow, Qing Duan, Kim de Jong, Mary K. Wojczynski, Xin-Qun Wang, Raymond Noordam, Fernando Pires Hartwig, Victoria E. Jackson, Tianyuan Wang, Ma’en Obeidat, Brian D. Hobbs, Tianxiao Huan, Hongsheng Gui, Margaret M. Parker, Donglei Hu, Lauren S. Mogil, Gleb Kichaev, Jianping Jin, Mariaelisa Graff, Tamara B. Harris, Ravi Kalhan, Susan R. Heckbert, Lavinia Paternoster, Kristin M. Burkart, Yongmei Liu, Elizabeth G. Holliday, James G. Wilson, Judith M. Vonk, Jason L. Sanders, R. Graham Barr, Renée de Mutsert, Ana Maria Baptista Menezes, Hieab H. H. Adams, Maarten van den Berge, Roby Joehanes, Albert M. Levin, Jennifer Liberto, Lenore J. Launer, Alanna C. Morrison, Colleen M. Sitlani, Juan C. Celedón, Stephen B. Kritchevsky, Rodney J. Scott, Kaare Christensen, Jerome I. Rotter, Tobias N. Bonten, Fernando César Wehrmeister, Yohan Bossé, Shujie Xiao, Sam Oh, Nora Franceschini, Jennifer A. Brody, Robert C. Kaplan, Kurt Lohman, Mark McEvoy, Michael A. Province, Frits R. Rosendaal, Kent D. Taylor, David C. Nickle, L. Keoki Williams, Esteban G. Burchard, Heather E. Wheeler, Don D. Sin, Vilmundur Gudnason, Kari E. North, Myriam Fornage, Bruce M. Psaty, Richard H. Myers, George O’Connor, Torben Hansen, Cathy C. Laurie, Patricia A. Cassano, Joohon Sung, Woo Jin Kim, John R. Attia, Leslie Lange, H. Marike Boezen, Bharat Thyagarajan, Stephen S. Rich, Dennis O. Mook-Kanamori, Bernardo Lessa Horta, André G. Uitterlinden, Hae Kyung Im, Michael H. Cho, Guy G. Brusselle, Sina A. Gharib, Josée Dupuis, Ani Manichaikul, Stephanie J. London
Published 2018-07-01

Genome-wide association and functional follow-up reveals new loci for kidney function.

by Cristian Pattaro, Anna Köttgen, Alexander Teumer, Maija Garnaas, Carsten A Böger, Christian Fuchsberger, Matthias Olden, Ming-Huei Chen, Adrienne Tin, Daniel Taliun, Man Li, Xiaoyi Gao, Mathias Gorski, Qiong Yang, Claudia Hundertmark, Meredith C Foster, Conall M O'Seaghdha, Nicole Glazer, Aaron Isaacs, Ching-Ti Liu, Albert V Smith, Jeffrey R O'Connell, Maksim Struchalin, Toshiko Tanaka, Guo Li, Andrew D Johnson, Hinco J Gierman, Mary Feitosa, Shih-Jen Hwang, Elizabeth J Atkinson, Kurt Lohman, Marilyn C Cornelis, Åsa Johansson, Anke Tönjes, Abbas Dehghan, Vincent Chouraki, Elizabeth G Holliday, Rossella Sorice, Zoltan Kutalik, Terho Lehtimäki, Tõnu Esko, Harshal Deshmukh, Sheila Ulivi, Audrey Y Chu, Federico Murgia, Stella Trompet, Medea Imboden, Barbara Kollerits, Giorgio Pistis, CARDIoGRAM Consortium, ICBP Consortium, CARe Consortium, Wellcome Trust Case Control Consortium 2 (WTCCC2), Tamara B Harris, Lenore J Launer, Thor Aspelund, Gudny Eiriksdottir, Braxton D Mitchell, Eric Boerwinkle, Helena Schmidt, Margherita Cavalieri, Madhumathi Rao, Frank B Hu, Ayse Demirkan, Ben A Oostra, Mariza de Andrade, Stephen T Turner, Jingzhong Ding, Jeanette S Andrews, Barry I Freedman, Wolfgang Koenig, Thomas Illig, Angela Döring, H-Erich Wichmann, Ivana Kolcic, Tatijana Zemunik, Mladen Boban, Cosetta Minelli, Heather E Wheeler, Wilmar Igl, Ghazal Zaboli, Sarah H Wild, Alan F Wright, Harry Campbell, David Ellinghaus, Ute Nöthlings, Gunnar Jacobs, Reiner Biffar, Karlhans Endlich, Florian Ernst, Georg Homuth, Heyo K Kroemer, Matthias Nauck, Sylvia Stracke, Uwe Völker, Henry Völzke, Peter Kovacs, Michael Stumvoll, Reedik Mägi, Albert Hofman, Andre G Uitterlinden, Fernando Rivadeneira, Yurii S Aulchenko, Ozren Polasek, Nick Hastie, Veronique Vitart, Catherine Helmer, Jie Jin Wang, Daniela Ruggiero, Sven Bergmann, Mika Kähönen, Jorma Viikari, Tiit Nikopensius, Michael Province, Shamika Ketkar, Helen Colhoun, Alex Doney, Antonietta Robino, Franco Giulianini, Bernhard K Krämer, Laura Portas, Ian Ford, Brendan M Buckley, Martin Adam, Gian-Andri Thun, Bernhard Paulweber, Margot Haun, Cinzia Sala, Marie Metzger, Paul Mitchell, Marina Ciullo, Stuart K Kim, Peter Vollenweider, Olli Raitakari, Andres Metspalu, Colin Palmer, Paolo Gasparini, Mario Pirastu, J Wouter Jukema, Nicole M Probst-Hensch, Florian Kronenberg, Daniela Toniolo, Vilmundur Gudnason, Alan R Shuldiner, Josef Coresh, Reinhold Schmidt, Luigi Ferrucci, David S Siscovick, Cornelia M van Duijn, Ingrid Borecki, Sharon L R Kardia, Yongmei Liu, Gary C Curhan, Igor Rudan, Ulf Gyllensten, James F Wilson, Andre Franke, Peter P Pramstaller, Rainer Rettig, Inga Prokopenko, Jacqueline C M Witteman, Caroline Hayward, Paul Ridker, Afshin Parsa, Murielle Bochud, Iris M Heid, Wolfram Goessling, Daniel I Chasman, W H Linda Kao, Caroline S Fox
Published 2012-01-01