A randomized placebo-controlled phase 3 study of mesenchymal stem cells induced to secrete high levels of neurotrophic factors in amyotrophic lateral sclerosis

by Aricha, R., Baloh, R.H, Berry, D.A, Berry, J.D, Brown, R.H., Jr, Burford, M.J, Cudkowicz, M.E, Gothelf, Y., Goyal, N.A, Jenkins, L.J, Katz, J.S, Kern, R.Z, Levy, Y.S, Lewis, R.A, Lindborg, S.R, Miller, R.G, Mozaffar, T., Nicholson, K.A, Owegi, M.A, Staff, N.P, Windebank, A.J
Published 2022

Adaptive Platform Trials to Transform Amyotrophic Lateral Sclerosis Therapy Development

by Ajroud-Driss, S., Alameda, G., Amber Malcolm, N.P, Andrews, J., Andrews, J., Appel, S.H, Arcila-Londono, X., Babu, S., Bailey, A., Bazan, T., Bedlack, R., Benatar, M., Benson, M., Berry, J., Berry, J.D, Bertorini, T., Bhuvaneswaran, K., Bind, M.A, Biostatisticians, Bocchio, S., Bolger, P., Bowser, R., Brown, R.H., Jr, Bulat, A., Burford, M., Caress, J., Cartwright, M., Chan, J., Changkuon, G., Chase, M., Chase, M., Chen, I.-H.A, Chibnik, L., Chibnik, L.B, Clawson, L., Clinical Operations Team, Cohen, J.A, Connolly, M., Cudkowicz, M., Cudkowicz, M.E, Dagostino, D., Davis, M., De Santiago, D., Deboo, A., Detry, M.A, Detry, M.A, Diaz, F., DiMarzio, M., DiOrio, N., DiStefano, S., Donofrio, P.D, Drake, K., Drake, K., Elliott, M., Elman, L., Eydinov, M., Farias, J., Faulconer, K., Fee, D., Feldman, E.L, Felice, K., Fernandes, J.A.M, Fetouh, A., Feulner, J., Figueroa-Szostek, P., for the Healey ALS Platform Trial Study Group, Foster, L., Fournier, C., Garozzo, T., Ghasemi, M., Gladden, C., Glass, J., Gomes, J., Goutman, S.A, Govindarajan, R., Goyal, N.A, Grabert, S., Granit, V., Greene, E., Grogan, J., Hall, M., Hamilton, J., Harkey, B., Hayat, G., HEALEY ALS Platform Trial Study Group, Heiman-Patterson, T., Heitzman, D., Henrique, J., Ilieva, H., Investigators, Jabari, D., Jackson, C., Jacobsen, B., Jawdat, O., Jenkins, L., Jentoft, K., Jin, P., Johnson, K., Jones, V., Judith Guarnieri, N.P, Julia Yasek, N.P, Kamp, C., Kasarskis, E.J, Katsovskiy, I., Katz, J., Kennedy, E., Kennedy, J., Kharakozova, O., Kittle, G., Kolb, S., Korin, A., Ladha, S., Lavery, C., Lewis, R., Li, X., Liao, B., Lim, S., Locatelli, E., Macklin, E., Macklin, E., Maiser, S., Mamarabadi, M., Maragakis, N.J, Martinez-Thompson, J., Mattos, A.D, McCaffrey, A., McGarry, A., McIlduff, C., Medical Monitors, Miller, T., Mosmiller, B., Nance, C., Nasri, M.A, Nathan, Newman, D.S, Nicholson, K., Novak, I., Olney, N., Oskarsson, B., Ostrow, J., Owegi, M.A, Paganoni, S., Paganoni, S., Pasinelli, P., Pattee, G.L, Patterson, J., Peltier, A.C, Piccione, E., Pothier, L., Quick, A., Quinn, C., Quintana, M., Quintana, M., Rad, N., Randall, R., Rezania, K., Riley, K., Rosenfeld, J., Russell, J.W, Rutkove, S., Sarah Heintzman, N.P, Saville, B., Saville, B.R, Scalia, J., Scott, R., Shah, J., Shaughnessy, A., Shefner, J., Shefner, J., Sherman, A., Sherman, A.V, Shroff, S., Simmons, Z., Sinani, E., Small, C., Statland, J., Steijlen, K., Stommel, E., Su, X., Suresh, N., Swenson, A., Tarasenko, N., Thaisetthawatkul, P., Thonhoff, J., Torti, M., Tourenne, C.L, Tustison, E., Twydell, P., Uchil, A., Vakili, G.S, Vestrucci, M., Vestrucci, M., Vigneswaran, P., Vu, T., Wahab, Y., Walk, D., Weiss, M.D, Whitaker, C., Whitworth, I., Wymer, J.P, Young, E., Yu, H., Yu, H.
Published 2022