Novel genetic variants in MAPT and alterations in tau phosphorylation in amyotrophic lateral sclerosis post-mortem motor cortex and cerebrospinal fluid

by Amaral, A.C, Arnold, S.E, Berry, J.D, Bordt, E., Chan, J., Commins, C., Connors, T., Cudkowicz, M.E, Dooley, P.M, Dujardin, S., Farhan, S.M.K, Ghosal, A., Gomez-Isla, T., Hyman, B.T, Kim, S.E, Kivisäkk, P., Mills, A.N, Oakley, D.H, Petrozziello, T., Sadri-Vakili, G., Spires-Jones, T., Trombetta, B.A
Published 2022

A randomized placebo-controlled phase 3 study of mesenchymal stem cells induced to secrete high levels of neurotrophic factors in amyotrophic lateral sclerosis

by Aricha, R., Baloh, R.H, Berry, D.A, Berry, J.D, Brown, R.H., Jr, Burford, M.J, Cudkowicz, M.E, Gothelf, Y., Goyal, N.A, Jenkins, L.J, Katz, J.S, Kern, R.Z, Levy, Y.S, Lewis, R.A, Lindborg, S.R, Miller, R.G, Mozaffar, T., Nicholson, K.A, Owegi, M.A, Staff, N.P, Windebank, A.J
Published 2022

A Phase 1 study of GDC-0134, a dual leucine zipper kinase inhibitor, in ALS

by Berry, J.D, Brooks, L., Brunstein, F., Burgess, B.L, Cheeti, S., Chen, C., Cho, W., Couch, J.A, Cudkowicz, M.E, Galanter, J., Genge, A., Ghosh, A.S, Glass, J.D, Hains, A.B, Honigberg, L., Katz, J.S, Kerchner, G.A, Oskarsson, B., Rothenberg, M.E, Rothstein, J.D, Sharma, K.R, van den Berg, L., Yeh, F.L
Published 2022

Adaptive Platform Trials to Transform Amyotrophic Lateral Sclerosis Therapy Development

by Ajroud-Driss, S., Alameda, G., Amber Malcolm, N.P, Andrews, J., Andrews, J., Appel, S.H, Arcila-Londono, X., Babu, S., Bailey, A., Bazan, T., Bedlack, R., Benatar, M., Benson, M., Berry, J., Berry, J.D, Bertorini, T., Bhuvaneswaran, K., Bind, M.A, Biostatisticians, Bocchio, S., Bolger, P., Bowser, R., Brown, R.H., Jr, Bulat, A., Burford, M., Caress, J., Cartwright, M., Chan, J., Changkuon, G., Chase, M., Chase, M., Chen, I.-H.A, Chibnik, L., Chibnik, L.B, Clawson, L., Clinical Operations Team, Cohen, J.A, Connolly, M., Cudkowicz, M., Cudkowicz, M.E, Dagostino, D., Davis, M., De Santiago, D., Deboo, A., Detry, M.A, Detry, M.A, Diaz, F., DiMarzio, M., DiOrio, N., DiStefano, S., Donofrio, P.D, Drake, K., Drake, K., Elliott, M., Elman, L., Eydinov, M., Farias, J., Faulconer, K., Fee, D., Feldman, E.L, Felice, K., Fernandes, J.A.M, Fetouh, A., Feulner, J., Figueroa-Szostek, P., for the Healey ALS Platform Trial Study Group, Foster, L., Fournier, C., Garozzo, T., Ghasemi, M., Gladden, C., Glass, J., Gomes, J., Goutman, S.A, Govindarajan, R., Goyal, N.A, Grabert, S., Granit, V., Greene, E., Grogan, J., Hall, M., Hamilton, J., Harkey, B., Hayat, G., HEALEY ALS Platform Trial Study Group, Heiman-Patterson, T., Heitzman, D., Henrique, J., Ilieva, H., Investigators, Jabari, D., Jackson, C., Jacobsen, B., Jawdat, O., Jenkins, L., Jentoft, K., Jin, P., Johnson, K., Jones, V., Judith Guarnieri, N.P, Julia Yasek, N.P, Kamp, C., Kasarskis, E.J, Katsovskiy, I., Katz, J., Kennedy, E., Kennedy, J., Kharakozova, O., Kittle, G., Kolb, S., Korin, A., Ladha, S., Lavery, C., Lewis, R., Li, X., Liao, B., Lim, S., Locatelli, E., Macklin, E., Macklin, E., Maiser, S., Mamarabadi, M., Maragakis, N.J, Martinez-Thompson, J., Mattos, A.D, McCaffrey, A., McGarry, A., McIlduff, C., Medical Monitors, Miller, T., Mosmiller, B., Nance, C., Nasri, M.A, Nathan, Newman, D.S, Nicholson, K., Novak, I., Olney, N., Oskarsson, B., Ostrow, J., Owegi, M.A, Paganoni, S., Paganoni, S., Pasinelli, P., Pattee, G.L, Patterson, J., Peltier, A.C, Piccione, E., Pothier, L., Quick, A., Quinn, C., Quintana, M., Quintana, M., Rad, N., Randall, R., Rezania, K., Riley, K., Rosenfeld, J., Russell, J.W, Rutkove, S., Sarah Heintzman, N.P, Saville, B., Saville, B.R, Scalia, J., Scott, R., Shah, J., Shaughnessy, A., Shefner, J., Shefner, J., Sherman, A., Sherman, A.V, Shroff, S., Simmons, Z., Sinani, E., Small, C., Statland, J., Steijlen, K., Stommel, E., Su, X., Suresh, N., Swenson, A., Tarasenko, N., Thaisetthawatkul, P., Thonhoff, J., Torti, M., Tourenne, C.L, Tustison, E., Twydell, P., Uchil, A., Vakili, G.S, Vestrucci, M., Vestrucci, M., Vigneswaran, P., Vu, T., Wahab, Y., Walk, D., Weiss, M.D, Whitaker, C., Whitworth, I., Wymer, J.P, Young, E., Yu, H., Yu, H.
Published 2022