The Effects of Shiga Toxin 1, 2 and Their Subunits on Cytokine and Chemokine Expression by Human Macrophage-Like THP-1 Cells

by Jeremy R. Brandelli, Thomas P. Griener, Austin Laing, George Mulvey, Glen D. Armstrong
Published 2015-10-01

Effects of Nitric Oxide and Reactive Oxygen Species on HIF-1α Stabilization Following Clostridium Difficile Toxin Exposure of the Caco-2 Epithelial Cell Line

by Joshua Y. Lee, Simon A. Hirota, Louise E. Glover, Glen D. Armstrong, Paul L. Beck, Justin A. MacDonald
Published 2013-08-01

Lipopolysaccharide renders transgenic mice expressing human serum amyloid P component sensitive to Shiga toxin 2.

by Thomas P Griener, Jonathan G Strecker, Romney M Humphries, George L Mulvey, Carmen Fuentealba, Robert E W Hancock, Glen D Armstrong
Published 2011-01-01

Impact of the Nature and Size of the Polymeric Backbone on the Ability of Heterobifunctional Ligands to Mediate Shiga Toxin and Serum Amyloid P Component Ternary Complex Formation

by Glen D. Armstrong, George L. Mulvey, Thomas P. Griener, Ravin Narain, Zhicheng Deng, Marya Ahmed, Joanna M. Sadowska, Eugenia Paszkiewicz, Pavel I. Kitov, David R. Bundle
Published 2011-08-01

Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome

by Jaye M. Platnich, Hyunjae Chung, Arthur Lau, Christina F. Sandall, Adom Bondzi-Simpson, Huey-Miin Chen, Takanori Komada, Aaron C. Trotman-Grant, Jeremy R. Brandelli, Justin Chun, Paul L. Beck, Dana J. Philpott, Stephen E. Girardin, May Ho, Roger P. Johnson, Justin A. MacDonald, Glen D. Armstrong, Daniel A. Muruve
Published 2018-11-01