ATP-Binding and Hydrolysis in Inflammasome Activation

by Christina F. Sandall, Bjoern K. Ziehr, Justin A. MacDonald
Published 2020-10-01

Chemical Modulation of the 1-(Piperidin-4-yl)-1,3-dihydro-2<i>H</i>-benzo[d]imidazole-2-one Scaffold as a Novel NLRP3 Inhibitor

by Simone Gastaldi, Valentina Boscaro, Eleonora Gianquinto, Christina F. Sandall, Marta Giorgis, Elisabetta Marini, Federica Blua, Margherita Gallicchio, Francesca Spyrakis, Justin A. MacDonald, Massimo Bertinaria
Published 2021-06-01

Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome

by Jaye M. Platnich, Hyunjae Chung, Arthur Lau, Christina F. Sandall, Adom Bondzi-Simpson, Huey-Miin Chen, Takanori Komada, Aaron C. Trotman-Grant, Jeremy R. Brandelli, Justin Chun, Paul L. Beck, Dana J. Philpott, Stephen E. Girardin, May Ho, Roger P. Johnson, Justin A. MacDonald, Glen D. Armstrong, Daniel A. Muruve
Published 2018-11-01