Missing heritability and where to find it

by Santhosh Girirajan
Published 2017-05-01

Characterization of the Retinoic Acid Induced 1 Gene in Humans and Mice

by Girirajan, Santhosh
Published 2008

An interaction-based model for neuropsychiatric features of copy-number variants.

by Matthew Jensen, Santhosh Girirajan
Published 2019-01-01

Mapping a shared genetic basis for neurodevelopmental disorders

by Matthew Jensen, Santhosh Girirajan
Published 2017-12-01

Genetic subtypes, allelic effects, and convergent neurodevelopmental mechanisms

by Maitreya Das, Santhosh Girirajan
Published 2021-06-01

Molecular basis for phenotypic similarity of genetic disorders

by Vijay Kumar Pounraja, Santhosh Girirajan
Published 2019-04-01

Lessons from model organisms: phenotypic robustness and missing heritability in complex disease.

by Christine Queitsch, Keisha D Carlson, Santhosh Girirajan
Published 2012-01-01

Improving the Power of Structural Variation Detection by Augmenting the Reference.

by Jan Schröder, Santhosh Girirajan, Anthony T Papenfuss, Paul Medvedev
Published 2015-01-01

Novel metrics to measure coverage in whole exome sequencing datasets reveal local and global non-uniformity

by Qingyu Wang, Cooduvalli S. Shashikant, Matthew Jensen, Naomi S. Altman, Santhosh Girirajan
Published 2017-04-01

Multi-Classifier Feature Fusion-Based Road Detection for Connected Autonomous Vehicles

by Prabu Subramani, Khalid Nazim Abdul Sattar, Rocío Pérez de Prado, Balasubramanian Girirajan, Marcin Wozniak
Published 2021-08-01

Dissecting the genetic basis of comorbid epilepsy phenotypes in neurodevelopmental disorders

by Julie Chow, Matthew Jensen, Hajar Amini, Farhad Hormozdiari, Osnat Penn, Sagiv Shifman, Santhosh Girirajan, Fereydoun Hormozdiari
Published 2019-10-01

A duplication CNV that conveys traits reciprocal to metabolic syndrome and protects against diet-induced obesity in mice and men.

by Melanie Lacaria, Pradip Saha, Lorraine Potocki, Weimin Bi, Jiong Yan, Santhosh Girirajan, Brooke Burns, Sarah Elsea, Katherina Walz, Lawrence Chan, James R Lupski, Wenli Gu
Published 2012-01-01

Drosophila models of pathogenic copy-number variant genes show global and non-neuronal defects during development.

by Tanzeen Yusuff, Matthew Jensen, Sneha Yennawar, Lucilla Pizzo, Siddharth Karthikeyan, Dagny J Gould, Avik Sarker, Erika Gedvilaite, Yurika Matsui, Janani Iyer, Zhi-Chun Lai, Santhosh Girirajan
Published 2020-06-01

Genetic studies in Drosophila and humans support a model for the concerted function of CISD2, PPT1 and CLN3 in disease

by Melanie A. Jones, Sami Amr, Aerial Ferebee, Phung Huynh, Jill A. Rosenfeld, Michael F. Miles, Andrew G. Davies, Christopher A. Korey, John M. Warrick, Rita Shiang, Sarah H. Elsea, Santhosh Girirajan, Mike Grotewiel
Published 2014-04-01

NCBP2 modulates neurodevelopmental defects of the 3q29 deletion in Drosophila and Xenopus laevis models.

by Mayanglambam Dhruba Singh, Matthew Jensen, Micaela Lasser, Emily Huber, Tanzeen Yusuff, Lucilla Pizzo, Brian Lifschutz, Inshya Desai, Alexis Kubina, Sneha Yennawar, Sydney Kim, Janani Iyer, Diego E Rincon-Limas, Laura Anne Lowery, Santhosh Girirajan
Published 2020-02-01

Relative burden of large CNVs on a range of neurodevelopmental phenotypes.

by Santhosh Girirajan, Zoran Brkanac, Bradley P Coe, Carl Baker, Laura Vives, Tiffany H Vu, Neil Shafer, Raphael Bernier, Giovanni B Ferrero, Margherita Silengo, Stephen T Warren, Carlos S Moreno, Marco Fichera, Corrado Romano, Wendy H Raskind, Evan E Eichler
Published 2011-11-01

Quantitative Assessment of Eye Phenotypes for Functional Genetic Studies Using Drosophila melanogaster

by Janani Iyer, Qingyu Wang, Thanh Le, Lucilla Pizzo, Sebastian Grönke, Surendra S. Ambegaokar, Yuzuru Imai, Ashutosh Srivastava, Beatriz Llamusí Troisí, Graeme Mardon, Ruben Artero, George R. Jackson, Adrian M. Isaacs, Linda Partridge, Bingwei Lu, Justin P. Kumar, Santhosh Girirajan
Published 2016-05-01

Pervasive genetic interactions modulate neurodevelopmental defects of the autism-associated 16p11.2 deletion in Drosophila melanogaster

by Janani Iyer, Mayanglambam Dhruba Singh, Matthew Jensen, Payal Patel, Lucilla Pizzo, Emily Huber, Haley Koerselman, Alexis T. Weiner, Paola Lepanto, Komal Vadodaria, Alexis Kubina, Qingyu Wang, Abigail Talbert, Sneha Yennawar, Jose Badano, J. Robert Manak, Melissa M. Rolls, Arjun Krishnan, Santhosh Girirajan
Published 2018-06-01

Functional assessment of the "two-hit" model for neurodevelopmental defects in Drosophila and X. laevis.

by Lucilla Pizzo, Micaela Lasser, Tanzeen Yusuff, Matthew Jensen, Phoebe Ingraham, Emily Huber, Mayanglambam Dhruba Singh, Connor Monahan, Janani Iyer, Inshya Desai, Siddharth Karthikeyan, Dagny J Gould, Sneha Yennawar, Alexis T Weiner, Vijay Kumar Pounraja, Arjun Krishnan, Melissa M Rolls, Laura Anne Lowery, Santhosh Girirajan
Published 2021-04-01