Substitution of Mannan-Binding Lectin (MBL)-Deficient Serum With Recombinant MBL Results in the Formation of New MBL/MBL-Associated Serine Protease Complexes

by Mischa P. Keizer, Mischa P. Keizer, Angela Kamp, Gerard van Mierlo, Taco W. Kuijpers, Taco W. Kuijpers, Diana Wouters
Published 2018-06-01

Sugar Matters: Improving In Vivo Clearance Rate of Highly Glycosylated Recombinant Plasma Proteins for Therapeutic Use

by Sacha Zeerleder, Ruchira Engel, Tao Zhang, Dorina Roem, Gerard van Mierlo, Ineke Wagenaar-Bos, Sija Marieke van Ham, Manfred Wuhrer, Diana Wouters, Ilse Jongerius
Published 2021-01-01

Human plasma-derived C1 esterase inhibitor concentrate has limited effect on house dust mite-induced allergic lung inflammation in mice.

by Ingrid Stroo, Jack Yang, Adam A Anas, J Daan de Boer, Gerard van Mierlo, Dorina Roem, Diana Wouters, Ruchira Engel, Joris J T H Roelofs, Cornelis van 't Veer, Tom van der Poll, Sacha Zeerleder
Published 2017-01-01

The effects of tidal volume size and driving pressure levels on pulmonary complement activation: an observational study in critically ill patients

by Friso M. de Beer, Luuk Wieske, Gerard van Mierlo, Diana Wouters, Sacha Zeerleder, Lieuwe D. Bos, Nicole P. Juffermans, Marcus J. Schultz, Tom van der Poll, Wim K. Lagrand, Janneke Horn, for the BASIC–study group
Published 2020-12-01

Complement factor H contributes to mortality in humans and mice with bacterial meningitis

by E. Soemirien Kasanmoentalib, Mercedes Valls Serón, Joo Yeon Engelen-Lee, Michael W. Tanck, Richard B. Pouw, Gerard van Mierlo, Diana Wouters, Matthew C. Pickering, Arie van der Ende, Taco W. Kuijpers, Matthijs C. Brouwer, Diederik van de Beek
Published 2019-12-01

Factor H-Related (FHR)-1 and FHR-2 Form Homo- and Heterodimers, while FHR-5 Circulates Only As Homodimer in Human Plasma

by Anna E. van Beek, Anna E. van Beek, Richard B. Pouw, Richard B. Pouw, Mieke C. Brouwer, Gerard van Mierlo, Judy Geissler, Pleuni Ooijevaar-de Heer, Martin de Boer, Karin van Leeuwen, Theo Rispens, Diana Wouters, Taco W. Kuijpers, Taco W. Kuijpers
Published 2017-10-01

Dynamics of antibodies to SARS‐CoV‐2 in convalescent plasma donors

by Maurice Steenhuis, Gerard vanMierlo, Ninotska IL Derksen, Pleuni Ooijevaar‐de Heer, Simone Kruithof, Floris L Loeff, Lea C Berkhout, Federica Linty, Chantal Reusken, Johan Reimerink, Boris Hogema, Hans Zaaijer, Leo van deWatering, Francis Swaneveld, Marit J vanGils, Berend Jan Bosch, S Marieke vanHam, Anja tenBrinke, Gestur Vidarsson, Ellen C van derSchoot, Theo Rispens
Published 2021-01-01