The relationship between vitamin C status, the gut-liver axis, and metabolic syndrome

by Maret G. Traber, Garry R. Buettner, Richard S. Bruno
Published 2019-02-01

Linking Cancer Metabolic Dysfunction and Genetic Instability through the Lens of Iron Metabolism

by Michael S. Petronek, Douglas R. Spitz, Garry R. Buettner, Bryan G. Allen
Published 2019-07-01

Understanding the Redox Biology of Selenium in the Search of Targeted Cancer Therapies

by Jeffrey M. Stolwijk, Rohan Garje, Jessica C. Sieren, Garry R. Buettner, Yousef Zakharia
Published 2020-05-01

Peroxiporin Expression Is an Important Factor for Cancer Cell Susceptibility to Therapeutic H2O2: Implications for Pharmacological Ascorbate Therapy.

by Dieanira Erudaitius, Andrew Huang, Sarah Kazmi, Garry R Buettner, Victor G J Rodgers
Published 2017-01-01

An assay for the rate of removal of extracellular hydrogen peroxide by cells

by Brett A. Wagner, Jordan R. Witmer, Thomas J. van't Erve, Garry R. Buettner
Published 2013-01-01

Moles of a Substance per Cell Is a Highly Informative Dosing Metric in Cell Culture.

by Claire M Doskey, Thomas J van 't Erve, Brett A Wagner, Garry R Buettner
Published 2015-01-01

Simultaneous detection of the enzyme activities of GPx1 and GPx4 guide optimization of selenium in cell biological experiments

by Jeffrey M. Stolwijk, Kelly C. Falls-Hubert, Charles C. Searby, Brett A. Wagner, Garry R. Buettner
Published 2020-05-01

Pharmacological ascorbate and ionizing radiation (IR) increase labile iron in pancreatic cancer

by Justin C. Moser, Malvika Rawal, Brett A. Wagner, Juan Du, Joseph J. Cullen, Garry R. Buettner
Published 2014-01-01

Direct spectrophotometric measurement of supra-physiological levels of ascorbate in plasma

by Jordan R. Witmer, Bailey J. Wetherell, Brett A. Wagner, Juan Du, Joseph J. Cullen, Garry R. Buettner
Published 2016-08-01

Methylseleninic Acid Induces Lipid Peroxidation and Radiation Sensitivity in Head and Neck Cancer Cells

by John T. Lafin, Ehab H. Sarsour, Amanda L. Kalen, Brett A. Wagner, Garry R. Buettner, Prabhat C. Goswami
Published 2019-01-01

Tumor cells have decreased ability to metabolize H2O2: Implications for pharmacological ascorbate in cancer therapy

by Claire M. Doskey, Visarut Buranasudja, Brett A. Wagner, Justin G. Wilkes, Juan Du, Joseph J. Cullen, Garry R. Buettner
Published 2016-12-01

Red blood cells contain enzymatically active GPx4 whose abundance anticorrelates with hemolysis during blood bank storage

by Jeffrey M. Stolwijk, Jonathan A. Stefely, Mike T. Veling, Thomas J. van ‘t Erve, Brett A. Wagner, Thomas J. Raife, Garry R. Buettner
Published 2021-10-01

Catalase Modulates the Radio-Sensitization of Pancreatic Cancer Cells by Pharmacological Ascorbate

by Juan Du, Rory S. Carroll, Garett J. Steers, Brett A. Wagner, Brianne R. O’Leary, Chris S. Jensen, Garry R. Buettner, Joseph J. Cullen
Published 2021-04-01

Hydrogen Peroxide Mediates Artemisinin-Derived C-16 Carba-Dimer-Induced Toxicity of Human Cancer Cells

by Amanda L. Kalen, Brett A. Wagner, Ehab H. Sarsour, Maneesh G. Kumar, Jessica L. Reedy, Garry R. Buettner, Nabin C. Barua, Prabhat C. Goswami
Published 2020-01-01

In vitro Cytotoxicity and Pharmacokinetic Evaluation of Pharmacological Ascorbate in Dogs

by Margaret L. Musser, Alyssa L. Mahaffey, Melissa A. Fath, Garry R. Buettner, Brett A. Wagner, Benjamin K. Schneider, Yeon-Jung Seo, Jonathan P. Mochel, Chad M. Johannes
Published 2019-11-01

Redox active metals and H2O2 mediate the increased efficacy of pharmacological ascorbate in combination with gemcitabine or radiation in pre-clinical sarcoma models

by Joshua D. Schoenfeld, Zita A. Sibenaller, Kranti A. Mapuskar, Megan D. Bradley, Brett A. Wagner, Garry R. Buettner, Varun Monga, Mohammed Milhem, Douglas R. Spitz, Bryan G. Allen
Published 2018-04-01

Superoxide Dismutase Mimetic GC4419 Enhances the Oxidation of Pharmacological Ascorbate and Its Anticancer Effects in an H2O2-Dependent Manner

by Collin D. Heer, Andrew B. Davis, David B. Riffe, Brett A. Wagner, Kelly C. Falls, Bryan G. Allen, Garry R. Buettner, Robert A. Beardsley, Dennis P. Riley, Douglas R. Spitz
Published 2018-01-01

Augmentation of intracellular iron using iron sucrose enhances the toxicity of pharmacological ascorbate in colon cancer cells

by Kristin E. Brandt, Kelly C. Falls, Joshua D. Schoenfeld, Samuel N. Rodman, Zhimin Gu, Fenghuang Zhan, Joseph J. Cullen, Brett A. Wagner, Garry R. Buettner, Bryan G. Allen, Daniel J. Berg, Douglas R. Spitz, Melissa A. Fath
Published 2018-04-01

Triphenylphosphonium derivatives disrupt metabolism and inhibit melanoma growth in vivo when delivered via a thermosensitive hydrogel.

by Kyle C Kloepping, Alora S Kraus, Devin K Hedlund, Colette M Gnade, Brett A Wagner, Michael L McCormick, Melissa A Fath, Dongrim Seol, Tae-Hong Lim, Garry R Buettner, Prabhat C Goswami, F Christopher Pigge, Douglas R Spitz, Michael K Schultz
Published 2020-01-01

Magnetic resonance imaging (MRI) of pharmacological ascorbate-induced iron redox state as a biomarker in subjects undergoing radio-chemotherapy

by Cameron M. Cushing, Michael S. Petronek, Kellie L. Bodeker, Sandy Vollstedt, Heather A. Brown, Emyleigh Opat, Nancy J. Hollenbeck, Thomas Shanks, Daniel J. Berg, Brian J. Smith, Mark C. Smith, Varun Monga, Muhammad Furqan, Matthew A. Howard, Jeremy D. Greenlee, Kranti A. Mapuskar, Joel St-Aubin, Ryan T. Flynn, Joseph J. Cullen, Garry R. Buettner, Douglas R. Spitz, John M. Buatti, Bryan G. Allen, Vincent A. Magnotta
Published 2021-01-01