Polymorphisms in signal transducer and activator of transcription 3 and lung function in asthma

by Litonjua, Augusto A., Tantisira, Kelan G., Lake, Stephen, Lazarus, Ross, Richter, Brent G., Gabriel, Stacey B., Silverman, Eric S., Weiss, Scott T.
Published 2010

Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability

by Drier, Yotam, Lawrence, Michael S., Carter, Scott L., Stewart, Chip, Gabriel, Stacey B., Meyerson, Matthew L., Beroukhim, Rameen, Getz, Gad, Lander, Eric Steven
Published 2013

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

by Cibulskis, Kristian, Sivachenko, Andrey, Jaffe, David B., Sougnez, Carrie, Gabriel, Stacey B., Meyerson, Matthew L., Getz, Gad, Lawrence, Michael S., Carter, Scott L., Lander, Eric Steven
Published 2014

Discovery and saturation analysis of cancer genes across 21 tumour types

by Lawrence, Michael S., Stojanov, Petar, Mermel, Craig H., Robinson, James T., Garraway, Levi A., Golub, Todd R., Meyerson, Matthew L., Gabriel, Stacey B., Getz, Gad, Lander, Eric Steven
Published 2015

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

by McKenna, Aaron, Hanna, Matthew, Sivachenko, Andrey, Cibulskis, Kristian, Kernytsky, Andrew, Garimella, Kiran, Altshuler, David, Gabriel, Stacey B., Daly, Mark J., DePristo, Mark A., Banks, Eric 1976-
Published 2014

Whole-Exome Sequencing and Homozygosity Analysis Implicate Depolarization-Regulated Neuronal Genes in Autism

by Chahrour, Maria H., Yu, Timothy W., Lim, Elaine T., Ataman, Bulent, Coulter, Michael E., Hill, R. Sean, Stevens, Christine R., Schubert, Christian R., Greenberg, Michael E., Gabriel, Stacey B., Walsh, Christopher A.
Published 2012

Discovery and characterization of artifactual mutations in deep coverage targeted capture sequencing data due to oxidative DNA damage during sample preparation

by Costello, Maura, Pugh, Trevor J., Fennell, Timothy, Stewart, Chip, Lichtenstein, Lee, Meldrim, James C., Fostel, Jennifer L., Friedrich, Dennis C., Perrin, Danielle, Dionne, Danielle, Kim, Sharon, Gabriel, Stacey B., Fisher, Sheila, Getz, Gad, Lander, Eric Steven
Published 2014

Systematic Cell-Based Phenotyping of Missense Alleles Empowers Rare Variant Association Studies: A Case for LDLR and Myocardial Infarction

by Thormaehlen, Aenne S., Schuberth, Christian, Won, Hong-Hee, Blattmann, Peter, Joggerst-Thomalla, Brigitte, Theiss, Susanne, Asselta, Rosanna, Duga, Stefano, Merlini, Piera Angelica, Ardissino, Diego, Gabriel, Stacey B., Rader, Daniel J., Peloso, Gina M., Pepperkok, Rainer, Kathiresan, Sekar, Runz, Heiko, Lander, Eric Steven
Published 2015

RNF43 is frequently mutated in colorectal and endometrial cancers

by Giannakis, Marios, Hodis, Eran, Jasmine Mu, Xinmeng, Yamauchi, Mai, Rosenbluh, Joseph, Cibulskis, Kristian, Saksena, Gordon, Lawrence, Michael S, Qian, Zhi Rong, Nishihara, Reiko, Van Allen, Eliezer M, Hahn, William C, Gabriel, Stacey B, Getz, Gad, Ogino, Shuji, Fuchs, Charles S, Garraway, Levi A, Lander, Eric Steven
Published 2018

Initial genome sequencing and analysis of multiple myeloma

by Chapman, Michael A., Lawrence, Michael S., Keats, Jonathan J., Cibulskis, Kristian, Sougnez, Carrie, Schinzel, Anna C., Harview, Christina L., Brunet, Jean-Philippe, Ahmann, Gregory J., Adli, Mazhar, Anderson, Kenneth C., Ardlie, Kristin, Auclair, Daniel, Baker, Angela, Bergsagel, P. Leif, Bernstein, Bradley E., Drier, Yotam, Fonseca, Rafael, Gabriel, Stacey B., Lander, Eric Steven
Published 2014

Activating mTOR Mutations in a Patient with an Extraordinary Response on a Phase I Trial of Everolimus and Pazopanib

by Wagle, N., Grabiner, Brian C., Van Allen, E. M., Hodis, Eran, Jacobus, S., Supko, J. G., Stewart, M., Choueiri, T. K., Gandhi, L., Cleary, J. M., Elfiky, A. A., Taplin, M. E., Stack, E. C., Signoretti, S., Loda, Massimo, Shapiro, G. I., Gabriel, Stacey B., Kantoff, Philip W., Garraway, Levi A., Rosenberg, J. E., Sabatini, David, Lander, Eric Steven
Published 2015

Paired exome analysis of Barrett's esophagus and adenocarcinoma

by Stachler, Matthew D, Taylor-Weiner, Amaro, Peng, Shouyong, McKenna, Aaron, Agoston, Agoston T, Odze, Robert D, Davison, Jon M, Nason, Katie S, Loda, Massimo, Leshchiner, Ignaty, Stewart, Chip, Stojanov, Petar, Seepo, Sara, Lawrence, Michael S, Ferrer-Torres, Daysha, Lin, Jules, Chang, Andrew C, Gabriel, Stacey B, Beer, David G, Getz, Gad, Carter, Scott L, Bass, Adam J, Lander, Eric Steven
Published 2016

Paired exome analysis of Barrett's esophagus and adenocarcinoma

by Stachler, Matthew D, Taylor-Weiner, Amaro, Peng, Shouyong, McKenna, Aaron, Agoston, Agoston T, Odze, Robert D, Davison, Jon M, Nason, Katie S, Loda, Massimo, Leshchiner, Ignaty, Stewart, Chip, Stojanov, Petar, Seepo, Sara, Lawrence, Michael S, Ferrer-Torres, Daysha, Lin, Jules, Chang, Andrew C, Gabriel, Stacey B, Beer, David G, Getz, Gad, Carter, Scott L, Bass, Adam J, Lander, Eric Steven
Published 2017

Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence

by Genovese, Giulio, Kahler, Anna K., Handsaker, Robert E., Lindberg, Johan, Rose, Samuel A., Bakhoum, Samuel F., Chambert, Kimberly, Mick, Eran, Neale, Benjamin M., Fromer, Menachem, Purcell, Shaun M., Svantesson, Oscar, Landen, Mikael, Hoglund, Martin, Lehmann, Soren, Gabriel, Stacey B., Moran, Jennifer L., Sullivan, Patrick F., Sklar, Pamela, Gronberg, Henrik, Hultman, Christina M., McCarroll, Steven A., Lander, Eric Steven
Published 2015

Integrative analysis of the melanoma transcriptome

by Berger, Michael F., Levin, Joshua Z., Vijayendran, Krishna, Sivachenko, Andrey, Adiconis, Xian, Maguire, Jared, Johnson, Laura A., Robinson, James, Verhaak, Roel G., Sougnez, Carrie, Onofrio, Robert, Ziaugra, Liuda, Cibulskis, Kristian, Laine, Elisabeth, Barretina, Jordi, Winckler, Wendy, Fisher, David E., Getz, Gad, Meyerson, Matthew L., Jaffe, David B., Gabriel, Stacey B., Dummer, Reinhard, Gnirke, Andreas, Nusbaum, Chad, Garraway, Levi A., Lander, Eric Steven
Published 2012

Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia

by Landau, Dan A, Carter, Scott L., Stojanov, Petar, McKenna, Aaron, Stevenson, Kristen, Lawrence, Michael S., Sougnez, Carrie, Stewart, Chip, Sivachenko, Andrey, Wang, Lili, Wan, Youzhong, Zhang, Wandi, Shukla, Sachet A, Vartanov, Alexander, Fernandes, Stacey M., Saksena, Gordon, Cibulskis, Kristian, Tesar, Bethany, Gabriel, Stacey B., Hacohen, Nir, Meyerson, Matthew L., Neuberg, Donna S., Brown, Jennifer R., Getz, Gad, Wu, Catherine J, Lander, Eric Steven
Published 2014

Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution

by Kim, Hoon, Zheng, Siyuan, Amini, Seyed S., Virk, Selene M., Mikkelsen, Tom, Brat, Daniel J., Grimsby, Jonna, Sougnez, Carrie, Muller, Florian, Hu, Jian, Sloan, Andrew E., Cohen, Mark L., Van Meir, Erwin G., Scarpace, Lisa, Laird, Peter W., Weinstein, John N., Gabriel, Stacey B., Getz, Gad, Meyerson, Matthew L., Chin, Lynda, Barnholtz-Sloan, Jill S., Verhaak, Roel G.W, Lander, Eric Steven
Published 2015

Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab

by Cho, Jeonghee, Bass, Adam J., Lawrence, Michael S., Cibulskis, Kristian, Cho, Ahye, Lee, Shi-Nai, Yamauchi, Mai, Wagle, Nikhil, Pochanard, Panisa, Kim, Nayoung, Park, Angela K. J., Won, Jonghwa, Hur, Hyung-Suk, Greulich, Heidi, Ogino, Shuji, Sougnez, Carrie, Voet, Douglas, Tabernero, Josep, Jimenez, Jose, Baselga, Jose, Gabriel, Stacey B., Getz, Gad, Eck, Michael J., Park, Woong-Yang, Meyerson, Matthew L., Lander, Eric Steven
Published 2014

Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma

by Giannakis, Marios, Mu, Xinmeng Jasmine, Shukla, Sachet A, Qian, Zhi Rong, Cohen, Ofir, Nishihara, Reiko, Bahl, Samira, Cao, Yin, Amin-Mansour, Ali, Yamauchi, Mai, Sukawa, Yasutaka, Stewart, Chip, Rosenberg, Mara, Mima, Kosuke, Inamura, Kentaro, Nosho, Katsuhiko, Nowak, Jonathan A, Lawrence, Michael S, Giovannucci, Edward L, Chan, Andrew T, Ng, Kimmie, Meyerhardt, Jeffrey A, Van Allen, Eliezer M, Getz, Gad, Gabriel, Stacey B, Wu, Catherine J, Fuchs, Charles S, Ogino, Shuji, Garraway, Levi A, Lander, Eric Steven
Published 2018