SHH Signaling Pathway Drives Pediatric Bone Sarcoma Progression

by Frédéric Lézot, Isabelle Corre, Sarah Morice, Françoise Rédini, Franck Verrecchia
Published 2020-02-01

Ribosomopathies: New Therapeutic Perspectives

by Emilien Orgebin, François Lamoureux, Bertrand Isidor, Céline Charrier, Benjamin Ory, Frédéric Lézot, Marc Baud’huin
Published 2020-09-01

Role of RANKL (TNFSF11)-dependent osteopetrosis in the dental phenotype of Msx2 null mutant mice.

by Beatriz Castaneda, Yohann Simon, Didier Ferbus, Benoit Robert, Julie Chesneau, Christopher Mueller, Ariane Berdal, Frédéric Lézot
Published 2013-01-01

Small animal models for the study of bone sarcoma pathogenesis:characteristics, therapeutic interests and limitations

by Camille Jacques, Nathalie Renema, Frederic Lezot, Benjamin Ory, Carl R. Walkley, Agamemnon E. Grigoriadis, Dominique Heymann
Published 2018-09-01

RANK/RANKL/OPG Signalization Implication in Periodontitis: New Evidence from a RANK Transgenic Mouse Model

by Bouchra Sojod, Danielle Chateau, Christopher G. Mueller, Sylvie Babajko, Ariane Berdal, Frédéric Lézot, Beatriz Castaneda, Beatriz Castaneda
Published 2017-05-01

Maternal RANKL Reduces the Osteopetrotic Phenotype of Null Mutant Mouse Pups

by Benjamin Navet, Jorge William Vargas-Franco, Andrea Gama, Jérome Amiaud, Yongwon Choi, Hideo Yagita, Christopher G. Mueller, Françoise Rédini, Dominique Heymann, Beatriz Castaneda, Frédéric Lézot
Published 2018-11-01

ICG-001, an Inhibitor of the β-Catenin and cAMP Response Element-Binding Protein Dependent Gene Transcription, Decreases Proliferation but Enhances Migration of Osteosarcoma Cells

by Geoffroy Danieau, Sarah Morice, Sarah Renault, Régis Brion, Kevin Biteau, Jérôme Amiaud, Marie Cadé, Dominique Heymann, Frédéric Lézot, Franck Verrecchia, Françoise Rédini, Bénédicte Brounais-Le Royer
Published 2021-05-01

Origins of Alterations to <i>Rankl</i> Null Mutant Mouse Dental Root Development

by Andrea Gama, Jorge William Vargas-Franco, Diana Carolina Sánchez Mesa, Elizabeth Restrepo Bedoya, Jérome Amiaud, Sylvie Babajko, Ariane Berdal, Ana Carolina Acevedo, Dominique Heymann, Frédéric Lézot, Beatriz Castaneda
Published 2020-03-01

Primary Retention of Molars and RANKL Signaling Alteration during Craniofacial Growth

by Andrea Gama, Laura Maman, Jorge William Vargas-Franco, Rana Omar, Bénédicte Brounais-Le Royer, Hideo Yagita, Sylvie Babajko, Ariane Berdal, Ana Carolina Acevedo, Dominique Heymann, Frédéric Lézot, Beatriz Castaneda
Published 2020-03-01

The Intrinsic and Extrinsic Implications of RANKL/RANK Signaling in Osteosarcoma: From Tumor Initiation to Lung Metastases

by Benjamin Navet, Kosei Ando, Jorge William Vargas-Franco, Régis Brion, Jérome Amiaud, Kanji Mori, Hideo Yagita, Christopher G. Mueller, Franck Verrecchia, Clotilde Dumars, Marie-Françoise Heymann, Dominique Heymann, Frédéric Lézot
Published 2018-10-01

Sonic Hedgehog Signature in Pediatric Primary Bone Tumors: Effects of the GLI Antagonist GANT61 on Ewing’s Sarcoma Tumor Growth

by Mathilde Mullard, Marie Cadé, Sarah Morice, Maryne Dupuy, Geoffroy Danieau, Jérome Amiaud, Sarah Renault, Frédéric Lézot, Régis Brion, Rose Anne Thepault, Benjamin Ory, François Lamoureux, Isabelle Corre, Bénédicte Brounais-LeRoyer, Françoise Rédini, Franck Verrecchia
Published 2020-11-01