Hippo/YAP Signaling Pathway: A Promising Therapeutic Target in Bone Paediatric Cancers?

by Sarah Morice, Geoffroy Danieau, Françoise Rédini, Bénédicte Brounais-Le-Royer, Franck Verrecchia
Published 2020-03-01

New Insights about the Wnt/β-Catenin Signaling Pathway in Primary Bone Tumors and Their Microenvironment: A Promising Target to Develop Therapeutic Strategies?

by Geoffroy Danieau, Sarah Morice, Françoise Rédini, Franck Verrecchia, Bénédicte Brounais-Le Royer
Published 2019-07-01

TGF-β Signaling in Bone Remodeling and Osteosarcoma Progression

by Audrey Lamora, Julie Talbot, Mathilde Mullard, Benedicte Brounais-Le Royer, Françoise Redini, Franck Verrecchia
Published 2016-11-01

The YAP/TEAD Axis as a New Therapeutic Target in Osteosarcoma: Effect of Verteporfin and CA3 on Primary Tumor Growth

by Sarah Morice, Mathilde Mullard, Regis Brion, Maryne Dupuy, Sarah Renault, Robel Tesfaye, Bénédicte Brounais-Le Royer, Benjamin Ory, Françoise Redini, Franck Verrecchia
Published 2020-12-01

ICG-001, an Inhibitor of the β-Catenin and cAMP Response Element-Binding Protein Dependent Gene Transcription, Decreases Proliferation but Enhances Migration of Osteosarcoma Cells

by Geoffroy Danieau, Sarah Morice, Sarah Renault, Régis Brion, Kevin Biteau, Jérôme Amiaud, Marie Cadé, Dominique Heymann, Frédéric Lézot, Franck Verrecchia, Françoise Rédini, Bénédicte Brounais-Le Royer
Published 2021-05-01

Primary Retention of Molars and RANKL Signaling Alteration during Craniofacial Growth

by Andrea Gama, Laura Maman, Jorge William Vargas-Franco, Rana Omar, Bénédicte Brounais-Le Royer, Hideo Yagita, Sylvie Babajko, Ariane Berdal, Ana Carolina Acevedo, Dominique Heymann, Frédéric Lézot, Beatriz Castaneda
Published 2020-03-01

Overexpression of the Ubiquitin Specific Proteases USP43, USP41, USP27x and USP6 in Osteosarcoma Cell Lines: Inhibition of Osteosarcoma Tumor Growth and Lung Metastasis Development...

by Mélanie Lavaud, Mathilde Mullard, Robel Tesfaye, Jérôme Amiaud, Mélanie Legrand, Geoffroy Danieau, Régis Brion, Sarah Morice, Laura Regnier, Maryne Dupuy, Bénédicte Brounais-Le Royer, François Lamoureux, Benjamin Ory, Françoise Rédini, Franck Verrecchia
Published 2021-08-01

Sonic Hedgehog Signature in Pediatric Primary Bone Tumors: Effects of the GLI Antagonist GANT61 on Ewing’s Sarcoma Tumor Growth

by Mathilde Mullard, Marie Cadé, Sarah Morice, Maryne Dupuy, Geoffroy Danieau, Jérome Amiaud, Sarah Renault, Frédéric Lézot, Régis Brion, Rose Anne Thepault, Benjamin Ory, François Lamoureux, Isabelle Corre, Bénédicte Brounais-LeRoyer, Françoise Rédini, Franck Verrecchia
Published 2020-11-01