Biological Rationale for Targeting MEK/ERK Pathways in Anti-Cancer Therapy and to Potentiate Tumour Responses to Radiation

by Francesco Marampon, Carmela Ciccarelli, Bianca Maria Zani
Published 2019-05-01

Cellular and Molecular Mediators of Bone Metastatic Lesions

by Giulia Battafarano, Michela Rossi, Francesco Marampon, Andrea Del Fattore
Published 2018-06-01

Bone Control of Muscle Function

by Giulia Battafarano, Michela Rossi, Francesco Marampon, Salvatore Minisola, Andrea Del Fattore
Published 2020-02-01

Strategies for Bone Regeneration: From Graft to Tissue Engineering

by Giulia Battafarano, Michela Rossi, Viviana De Martino, Francesco Marampon, Luca Borro, Aurelio Secinaro, Andrea Del Fattore
Published 2021-01-01

Allosteric Modulators of G Protein-Coupled Dopamine and Serotonin Receptors: A New Class of Atypical Antipsychotics

by Irene Fasciani, Francesco Petragnano, Gabriella Aloisi, Francesco Marampon, Marco Carli, Marco Scarselli, Roberto Maggio, Mario Rossi
Published 2020-11-01

Sildenafil Counteracts the In Vitro Activation of CXCL-9, CXCL-10 and CXCL-11/CXCR3 Axis Induced by Reactive Oxygen Species in Scleroderma Fibroblasts

by Cristina Antinozzi, Paolo Sgrò, Francesco Marampon, Daniela Caporossi, Francesco Del Galdo, Ivan Dimauro, Luigi Di Luigi
Published 2021-05-01

The possible prognostic role of histone deacetylase and transforming growth factor β/Smad signaling in high grade gliomas treated by radio-chemotherapy: a preliminary immunohistoch...

by Roberta Sferra, Simona Pompili, Claudio Festuccia, Francesco Marampon, Giovanni L. Gravina, Luca Ventura, Ernesto Di Cesare, Sara Cicchinelli, Eugenio Gaudio, Antonella Vetuschi
Published 2017-05-01

The brain-penetrating CXCR4 antagonist, PRX177561, increases the antitumor effects of bevacizumab and sunitinib in preclinical models of human glioblastoma

by Giovanni Luca Gravina, Andrea Mancini, Francesco Marampon, Alessandro Colapietro, Simona Delle Monache, Roberta Sferra, Flora Vitale, Peter J. Richardson, Lee Patient, Stephen Burbidge, Claudio Festuccia
Published 2017-01-01

Phosphodiesterase Type-5 Inhibitor Tadalafil Modulates Steroid Hormones Signaling in a Prostate Cancer Cell Line

by Viviana M. Bimonte, Francesco Marampon, Ambra Antonioni, Simona Fittipaldi, Elisabetta Ferretti, Richard G. Pestell, Mariaignazia Curreli, Andrea Lenzi, Giovanni Vitale, Antonio Brunetti, Silvia Migliaccio, Antonio Aversa
Published 2021-01-01

Muscle Damage in Systemic Sclerosis and CXCL10: The Potential Therapeutic Role of PDE5 Inhibition

by Clarissa Corinaldesi, Rebecca L. Ross, Giuseppina Abignano, Cristina Antinozzi, Francesco Marampon, Luigi di Luigi, Maya H Buch, Valeria Riccieri, Andrea Lenzi, Clara Crescioli, Francesco Del Galdo
Published 2021-03-01

Treatment of Solitary Painful Osseous Metastases with Radiotherapy, Cryoablation or Combined Therapy: Propensity Matching Analysis in 175 Patients.

by Mario Di Staso, Giovanni Luca Gravina, Luigi Zugaro, Pierluigi Bonfili, Lorenzo Gregori, Pietro Franzese, Francesco Marampon, Francesca Vittorini, Roberto Moro, Vincenzo Tombolini, Ernesto Di Cesare, Carlo Masciocchi
Published 2015-01-01

OTX015 Epi-Drug Exerts Antitumor Effects in Ovarian Cancer Cells by Blocking GNL3-Mediated Radioresistance Mechanisms: Cellular, Molecular and Computational Evidence

by Francesca Megiorni, Simona Camero, Paola Pontecorvi, Lucrezia Camicia, Francesco Marampon, Simona Ceccarelli, Eleni Anastasiadou, Nicola Bernabò, Giorgia Perniola, Antonio Pizzuti, Pierluigi Benedetti Panici, Vincenzo Tombolini, Cinzia Marchese
Published 2021-03-01

The Brain Penetrating and Dual TORC1/TORC2 Inhibitor, RES529, Elicits Anti-Glioma Activity and Enhances the Therapeutic Effects of Anti-Angiogenetic Compounds in Preclinical Murine...

by Giovanni Luca Gravina, Andrea Mancini, Alessandro Colapietro, Simona Delle Monache, Roberta Sferra, Simona Pompili, Flora Vitale, Stefano Martellucci, Francesco Marampon, Vincenzo Mattei, Leda Biordi, David Sherris, Claudio Festuccia
Published 2019-10-01

The first-in-class alkylating deacetylase inhibitor molecule tinostamustine shows antitumor effects and is synergistic with radiotherapy in preclinical models of glioblastoma

by Claudio Festuccia, Andrea Mancini, Alessandro Colapietro, Giovanni Luca Gravina, Flora Vitale, Francesco Marampon, Simona Delle Monache, Simona Pompili, Loredana Cristiano, Antonella Vetuschi, Vincenzo Tombolini, Yi Chen, Thomas Mehrling
Published 2018-02-01

The novel CXCR4 antagonist, PRX177561, reduces tumor cell proliferation and accelerates cancer stem cell differentiation in glioblastoma preclinical models

by Giovanni Luca Gravina, Andrea Mancini, Alessandro Colapietro, Flora Vitale, Antonella Vetuschi, Simona Pompili, Giulia Rossi, Francesco Marampon, Peter J Richardson, Lee Patient, Lee Patient, Stephen Burbidge, Claudio Festuccia
Published 2017-06-01

One-week vaginal brachytherapy schedule as exclusive adjuvant post-operative treatment in intermediate- and high-intermediate-risk endometrial cancer patients

by Vitaliana De Sanctis, Daniela Musio, Francesca Felice, Francesco Marampon, Maurizio Valeriani, Paolo Bonome, Dimitri Anzellini, Giuseppe Facondo, Gianluca Vullo, Maria Massaro, Mario Di Staso, Pierluigi Bonfili, Agnieszka Chalaszczyk, Giovanni Gravina, Vincenzo Tombolini, Mattia Osti
Published 2020-04-01

The Small Molecule Ephrin Receptor Inhibitor, GLPG1790, Reduces Renewal Capabilities of Cancer Stem Cells, Showing Anti-Tumour Efficacy on Preclinical Glioblastoma Models

by Giovanni Luca Gravina, Andrea Mancini, Alessandro Colapietro, Simona Delle Monache, Roberta Sferra, Flora Vitale, Loredana Cristiano, Stefano Martellucci, Francesco Marampon, Vincenzo Mattei, Filip Beirinckx, Philippe Pujuguet, Laurent Saniere, Giocondo Lorenzon, Ellen van der Aar, Claudio Festuccia
Published 2019-03-01

MiR-200c-3p Contrasts PD-L1 Induction by Combinatorial Therapies and Slows Proliferation of Epithelial Ovarian Cancer through Downregulation of β-Catenin and c-Myc

by Eleni Anastasiadou, Elena Messina, Tiziana Sanavia, Lucia Mundo, Federica Farinella, Stefano Lazzi, Francesca Megiorni, Simona Ceccarelli, Paola Pontecorvi, Francesco Marampon, Cira Rosaria Tiziana Di Gioia, Giorgia Perniola, Pierluigi Benedetti Panici, Lorenzo Leoncini, Pankaj Trivedi, Andrea Lenzi, Cinzia Marchese
Published 2021-03-01

The Botanical Drug PBI-05204, a Supercritical CO2 Extract of Nerium Oleander, Inhibits Growth of Human Glioblastoma, Reduces Akt/mTOR Activities, and Modulates GSC Cell-Renewal Pro...

by Alessandro Colapietro, Peiying Yang, Alessandra Rossetti, Andrea Mancini, Flora Vitale, Stefano Martellucci, Stefano Martellucci, Tara L. Conway, Sharmistha Chakraborty, Francesco Marampon, Vincenzo Mattei, Giovanni Luca Gravina, Giovanni Luca Gravina, Assunta Leda Biordi, Daoyan Wei, Robert A. Newman, Claudio Festuccia
Published 2020-09-01

Antitumorigenic Effects of Inhibiting Ephrin Receptor Kinase Signaling by GLPG1790 against Colorectal Cancer Cell Lines In Vitro and In Vivo

by Alessandro Colapietro, Giovanni Luca Gravina, Francesco Petragnano, Irene Fasciani, Bianca Maria Scicchitano, Filip Beirinckx, Philippe Pujuguet, Laurent Saniere, Ellen Van der Aar, Daniela Musio, Francesca De Felice, Vincenzo Mattei, Stefano Martellucci, Roberto Maggio, Vincenzo Tombolini, Claudio Festuccia, Francesco Marampon
Published 2020-01-01