Regioselective synthesis and anti-inflammatory activity of novel dispiro[pyrazolidine-4,3'-pyrrolidine-2',3"-indoline]-2",3,5-triones

by Essam M. Hussein, Maisa I. Abdel-Monem
Published 2011-07-01

Structure-reactivity relationships on Michael additions of secondary cyclic amines with 3-cyanomethylidene-2-oxindoline derivatives

by Shaimaa Sindi, Nizar El Guesmi, Basim H. Asghar, Essam M. Hussein
Published 2020-05-01

Tailoring of novel biologically active molecules based on N4-substituted sulfonamides bearing thiazole moiety exhibiting unique multi-addressable biological potentials

by Essam M. Hussein, Munirah M. Al-Rooqi, Amal A. Elkhawaga, Saleh A. Ahmed
Published 2020-05-01

Design, synthesis, and biological evaluation of novel N 4 -substituted sulfonamides: acetamides derivatives as dihydrofolate reductase (DHFR) inhibitors

by Essam M. Hussein, Munirah M. Al-Rooqi, Shimaa M. Abd El-Galil, Saleh A. Ahmed
Published 2019-07-01

Bioactive fluorenes. part I. Synthesis, pharmacological study and molecular docking of novel dihydrofolate reductase inhibitors based-2,7-dichlorofluorene

by Essam M. Hussein, Reem I. Alsantali, Shimaa M. Abd El-Galil, Rami J. Obaid, Ahmed Alharbi, Mohamed A.S. Abourehab, Saleh A. Ahmed
Published 2019-06-01

Bioactive fluorenes. Part III: 2,7-dichloro-9H-fluorene-based thiazolidinone and azetidinone analogues as anticancer and antimicrobial against multidrug resistant strains agents

by Essam M. Hussein, Reem I. Alsantali, Moataz Morad, Rami J. Obaid, Hatem M. Altass, Ali Sayqal, Mohamed A. S. Abourehab, Amal A. Elkhawaga, Ahmed S. M. Aboraia, Saleh A. Ahmed
Published 2020-06-01

Nucleophilicity and solvent effects on the kinetics of 4-(pyren-1-yl)thiazol-2-amine interaction with 4,6-dinitrobenzofuroxan

by Nizar El Guesmi, Essam M. Hussein, Basim H. Asghar, Rami J. Obaid, Rabab S. Jassas, Ahmed Alharbi, Hatem M. Altass, Ismail I. Althagafi, Moataz Morad, Ziad Moussa, Saleh A. Ahmed
Published 2020-02-01

Bioactive Fluorenes. Part II. Unprecedented biologically active thiazole derivatives based-2,7-dichlorofluorene as competent DHFR inhibitors: Design, synthesis, and molecular docki...

by Reem I. Alsantali, Essam M. Hussein, Rami J. Obaid, Moataz Morad, Hatem M. Altass, Ahmed Alharbi, Ahmed M. Hameed, Rabab.S. Jassas, Mohamed A.S. Abourehab, Basim H. Asghar, Ziad Moussa, Saleh A. Ahmed
Published 2020-05-01