Bioactive fluorenes. part I. Synthesis, pharmacological study and molecular docking of novel dihydrofolate reductase inhibitors based-2,7-dichlorofluorene

by Essam M. Hussein, Reem I. Alsantali, Shimaa M. Abd El-Galil, Rami J. Obaid, Ahmed Alharbi, Mohamed A.S. Abourehab, Saleh A. Ahmed
Published 2019-06-01

Bioactive fluorenes. Part III: 2,7-dichloro-9H-fluorene-based thiazolidinone and azetidinone analogues as anticancer and antimicrobial against multidrug resistant strains agents

by Essam M. Hussein, Reem I. Alsantali, Moataz Morad, Rami J. Obaid, Hatem M. Altass, Ali Sayqal, Mohamed A. S. Abourehab, Amal A. Elkhawaga, Ahmed S. M. Aboraia, Saleh A. Ahmed
Published 2020-06-01

Bioactive Fluorenes. Part II. Unprecedented biologically active thiazole derivatives based-2,7-dichlorofluorene as competent DHFR inhibitors: Design, synthesis, and molecular docki...

by Reem I. Alsantali, Essam M. Hussein, Rami J. Obaid, Moataz Morad, Hatem M. Altass, Ahmed Alharbi, Ahmed M. Hameed, Rabab.S. Jassas, Mohamed A.S. Abourehab, Basim H. Asghar, Ziad Moussa, Saleh A. Ahmed
Published 2020-05-01

Novel Pyran-Linked Phthalazinone-Pyrazole Hybrids: Synthesis, Cytotoxicity Evaluation, Molecular Modeling, and Descriptor Studies

by M. Shaheer Malik, Basim H. Asghar, Riyaz Syed, Reem I. Alsantali, Moataz Morad, Hatem M. Altass, Hatem M. Altass, Ziad Moussa, Ismail I. Althagafi, Rabab S. Jassas, Saleh A. Ahmed, Saleh A. Ahmed
Published 2021-05-01

Molecular modelling assisted design of napthalimide-dihydropyrimidinone conjugates as potential cytotoxic agents

by M. Shaheer Malik, Syed Farooq Adil, Zaki S. Seddigi, Moataz Morad, Rabab S. Jassas, Ismail I. Thagafi, Hatem M. Altass, Qazi Mohammad Sajid Jamal, Syed Riyaz, Reem I. Alsantali, Abdulrahman A. Al-Warthan, Mohammad Azam Ansari, Saleh A. Ahmed
Published 2021-05-01