MCP1-CCR2 and neuroinflammation in the ALS motor cortex with TDP-43 pathology

by Javier H. Jara, Mukesh Gautam, Nuran Kocak, Edward F. Xie, Qinwen Mao, Eileen H. Bigio, P. Hande Özdinler
Published 2019-10-01

Activated Microglia in Cortical White Matter Across Cognitive Aging Trajectories

by Tamar Gefen, Tamar Gefen, Garam Kim, Kabriya Bolbolan, Andrew Geoly, Daniel Ohm, Carly Oboudiyat, Ryan Shahidehpour, Alfred Rademaker, Alfred Rademaker, Sandra Weintraub, Sandra Weintraub, Eileen H. Bigio, Eileen H. Bigio, M.-Marsel Mesulam, M.-Marsel Mesulam, Emily Rogalski, Emily Rogalski, Changiz Geula, Changiz Geula
Published 2019-05-01

Associations of MAP2K3 Gene Variants With Superior Memory in SuperAgers

by Matthew J. Huentelman, Ignazio S. Piras, Ashley L. Siniard, Matthew D. De Both, Ryan F. Richholt, Chris D. Balak, Pouya Jamshidi, Eileen H. Bigio, Eileen H. Bigio, Sandra Weintraub, Sandra Weintraub, Emmaleigh T. Loyer, M.-Marsel Mesulam, M.-Marsel Mesulam, Changiz Geula, Emily J. Rogalski, Emily J. Rogalski
Published 2018-05-01

Evidence for an early innate immune response in the motor cortex of ALS

by Javier H. Jara, Barış Genç, Macdonell J. Stanford, Peter Pytel, Raymond P. Roos, Sandra Weintraub, M. Marsel Mesulam, Eileen H. Bigio, Richard J. Miller, P. Hande Özdinler
Published 2017-06-01

FUS Interacts with HSP60 to Promote Mitochondrial Damage.

by Jianwen Deng, Mengxue Yang, Yanbo Chen, Xiaoping Chen, Jianghong Liu, Shufeng Sun, Haipeng Cheng, Yang Li, Eileen H Bigio, Marsel Mesulam, Qi Xu, Sidan Du, Kazuo Fushimi, Li Zhu, Jane Y Wu
Published 2015-09-01

TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response.

by Peng Wang, Jianwen Deng, Jie Dong, Jianghong Liu, Eileen H Bigio, Marsel Mesulam, Tao Wang, Lei Sun, Li Wang, Alan Yueh-Luen Lee, Warren A McGee, Xiaoping Chen, Kazuo Fushimi, Li Zhu, Jane Y Wu
Published 2019-05-01

Predictors of cognitive impairment in primary age-related tauopathy: an autopsy study

by Megan A. Iida, Kurt Farrell, Jamie M. Walker, Timothy E. Richardson, Gabriel A. Marx, Clare H. Bryce, Dushyant Purohit, Gai Ayalon, Thomas G. Beach, Eileen H. Bigio, Etty P. Cortes, Marla Gearing, Vahram Haroutunian, Corey T. McMillan, Edward B. Lee, Dennis W. Dickson, Ann C. McKee, Thor D. Stein, John Q. Trojanowski, Randall L. Woltjer, Gabor G. Kovacs, Julia K. Kofler, Jeffrey Kaye, Charles L. White, John F. Crary
Published 2021-08-01

Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis.

by Nicola J Rutherford, Yong-Jie Zhang, Matt Baker, Jennifer M Gass, Nicole A Finch, Ya-Fei Xu, Heather Stewart, Brendan J Kelley, Karen Kuntz, Richard J P Crook, Jemeen Sreedharan, Caroline Vance, Eric Sorenson, Carol Lippa, Eileen H Bigio, Daniel H Geschwind, David S Knopman, Hiroshi Mitsumoto, Ronald C Petersen, Neil R Cashman, Mike Hutton, Christopher E Shaw, Kevin B Boylan, Bradley Boeve, Neill R Graff-Radford, Zbigniew K Wszolek, Richard J Caselli, Dennis W Dickson, Ian R Mackenzie, Leonard Petrucelli, Rosa Rademakers
Published 2008-09-01

A molecular pathology, neurobiology, biochemical, genetic and neuroimaging study of progressive apraxia of speech

by Keith A. Josephs, Joseph R. Duffy, Heather M. Clark, Rene L. Utianski, Edythe A. Strand, Mary M. Machulda, Hugo Botha, Peter R. Martin, Nha Trang Thu Pham, Julie Stierwalt, Farwa Ali, Marina Buciuc, Matthew Baker, Cristhoper H. Fernandez De Castro, Anthony J. Spychalla, Christopher G. Schwarz, Robert I. Reid, Matthew L. Senjem, Clifford R. Jack, Val J. Lowe, Eileen H. Bigio, Ross R. Reichard, Eric. J. Polley, Nilufer Ertekin-Taner, Rosa Rademakers, Michael A. DeTure, Owen A. Ross, Dennis W. Dickson, Jennifer L. Whitwell
Published 2021-06-01