CD45RA+CCR7− CD8 T cells lacking co-stimulatory receptors demonstrate enhanced frequency in peripheral blood of NSCLC patients responding to nivolumab

by Andre Kunert, Edwin A. Basak, Daan P. Hurkmans, Hayri E. Balcioglu, Yarne Klaver, Mandy van Brakel, Astrid A. M. Oostvogels, Cor H. J. Lamers, Sander Bins, Stijn L. W. Koolen, Astrid A. M. van der Veldt, Stefan Sleijfer, Ron H. J. Mathijssen, Joachim G. J. V. Aerts, Reno Debets
Published 2019-06-01

Prospective real-world study on the pharmacokinetics of pembrolizumab in patients with solid tumors

by Markus Joerger, Reno Debets, Edwin A. Basak, Daan P. Hurkmans, Cor H. van der Leest, Sebastiaan D.T. Sassen, Karlijn de Joode, Lisanne Putter, Annemarie J.M. Wijkhuijs, Birgit C.P. Koch, Marco W.J. Schreurs, Astrid A.M. van der Veldt, Joachim G.J.V. Aerts, Ron H.J. Mathijssen, Stijn L.W. Koolen
Published 2021-06-01

A prospective cohort study on the pharmacokinetics of nivolumab in metastatic non-small cell lung cancer, melanoma, and renal cell cancer patients

by Daan P. Hurkmans, Edwin A. Basak, Tanja van Dijk, Darlene Mercieca, Marco W. J. Schreurs, Annemarie J. M. Wijkhuijs, Sander Bins, Esther Oomen-de Hoop, Reno Debets, Markus Joerger, Arlette Odink, Astrid A. M. van der Veldt, Cor H. van der Leest, Joachim G. J. V. Aerts, Ron H. J. Mathijssen, Stijn L. W. Koolen
Published 2019-07-01

Blood-based kinase activity profiling: a potential predictor of response to immune checkpoint inhibition in metastatic cancer

by Joachim G J V Aerts, Ron H J Mathijssen, Mandy van Brakel, Ellen Kapiteijn, Daan P Hurkmans, Els M E Verdegaal, Sabrina A Hogan, Rik de Wijn, Lies Hovestad, Dianne M A van den Heuvel, Rob Ruijtenbeek, Marij J P Welters, Edwin A Basak, Herbert M Pinedo, Cor H J Lamers, Harmen J G van de Werken, John P Groten, Mitchell P Levesque
Published 2020-07-01