Identification of adjuvants for clinical trials performed with Plasmodium falciparum AMA1 in rabbits

by Sumera Younis, Bart W. Faber, Clemens H.M. Kocken, Edmond J. Remarque
Published 2019-07-01

Humoral immune response to mixed PfAMA1 alleles; multivalent PfAMA1 vaccines induce broad specificity.

by Kwadwo A Kusi, Bart W Faber, Alan W Thomas, Edmond J Remarque
Published 2009-12-01

Generation of humoral immune responses to multi-allele PfAMA1 vaccines; effect of adjuvant and number of component alleles on the breadth of response.

by Kwadwo A Kusi, Bart W Faber, Vanessa Riasat, Alan W Thomas, Clemens H M Kocken, Edmond J Remarque
Published 2010-11-01

A malaria vaccine based on the polymorphic block 2 region of MSP-1 that elicits a broad serotype-spanning immune response.

by Graeme J M Cowan, Alison M Creasey, Kelwalin Dhanasarnsombut, Alan W Thomas, Edmond J Remarque, David R Cavanagh
Published 2011-01-01

The breadth, but not the magnitude, of circulating memory B cell responses to P. falciparum increases with age/exposure in an area of low transmission.

by Sarah I Nogaro, Julius C Hafalla, Brigitte Walther, Edmond J Remarque, Kevin K A Tetteh, David J Conway, Eleanor M Riley, Michael Walther
Published 2011-01-01

Serologically-Based Evaluation of Cross-Protection Antibody Responses among Different A(H1N1) Influenza Strains

by Serena Marchi, Ilaria Manini, Otfried Kistner, Pietro Piu, Edmond J. Remarque, Alessandro Manenti, Fabrizio Biuso, Tommaso Carli, Giacomo Lazzeri, Emanuele Montomoli, Claudia Maria Trombetta
Published 2020-11-01

Immune Responses to Pandemic H1N1 Influenza Virus Infection in Pigs Vaccinated with a Conserved Hemagglutinin HA1 Peptide Adjuvanted with CAF^®01 or CDA/αGalCerMPEG

by Sergi López-Serrano, Lorena Cordoba, Mónica Pérez-Maillo, Patricia Pleguezuelos, Edmond J. Remarque, Thomas Ebensen, Carlos A. Guzmán, Dennis Christensen, Joaquim Segalés, Ayub Darji
Published 2021-07-01

Evaluation of Chimpanzee Adenovirus and MVA Expressing TRAP and CSP from <i>Plasmodium cynomolgi</i> to Prevent Malaria Relapse in Nonhuman Primates

by Young Chan Kim, Barbara Dema, Roberto Rodriguez-Garcia, César López-Camacho, Fabiana M. S. Leoratti, Amar Lall, Edmond J. Remarque, Clemens H. M. Kocken, Arturo Reyes-Sandoval
Published 2020-07-01

The quantity and quality of African children's IgG responses to merozoite surface antigens reflect protection against Plasmodium falciparum malaria.

by David Courtin, Mayke Oesterholt, Harm Huismans, Kwadwo Kusi, Jacqueline Milet, Cyril Badaut, Oumar Gaye, Will Roeffen, Edmond J Remarque, Robert Sauerwein, André Garcia, Adrian J F Luty
Published 2009-10-01

Characterization of antibody response in asymptomatic and symptomatic SARS-CoV-2 infection.

by Serena Marchi, Simonetta Viviani, Edmond J Remarque, Antonella Ruello, Emilio Bombardieri, Valentina Bollati, Gregorio P Milani, Alessandro Manenti, Giulia Lapini, Annunziata Rebuffat, Emanuele Montomoli, Claudia M Trombetta
Published 2021-01-01

Vaccination with Plasmodium knowlesi AMA1 formulated in the novel adjuvant co-vaccine HT™ protects against blood-stage challenge in rhesus macaques.

by Muzamil Mahdi Abdel Hamid, Edmond J Remarque, Leonie M van Duivenvoorde, Nicole van der Werff, Vanessa Walraven, Bart W Faber, Clemens H M Kocken, Alan W Thomas
Published 2011-01-01

Humoral immune responses to a single allele PfAMA1 vaccine in healthy malaria-naïve adults.

by Edmond J Remarque, Meta Roestenberg, Sumera Younis, Vanessa Walraven, Nicole van der Werff, Bart W Faber, Odile Leroy, Robert Sauerwein, Clemens H M Kocken, Alan W Thomas
Published 2012-01-01

Low levels of polymorphisms and no evidence for diversifying selection on the Plasmodium knowlesi Apical Membrane Antigen 1 gene.

by Bart W Faber, Khamisah Abdul Kadir, Roberto Rodriguez-Garcia, Edmond J Remarque, Frederick A Saul, Brigitte Vulliez-Le Normand, Graham A Bentley, Clemens H M Kocken, Balbir Singh
Published 2015-01-01

Accelerated phase Ia/b evaluation of the malaria vaccine candidate PfAMA1 DiCo demonstrates broadening of humoral immune responses

by Edmond J. Remarque, Bart W. Faber, Roberto Rodriguez Garcia, Herman Oostermeijer, Sodiomon B. Sirima, Issa Nebie Ouedraogo, Leila Kara, Odile Launay, Sophie Houard, Odile Leroy, Clemens H. M. Kocken
Published 2021-04-01

Chemoprophylaxis with sporozoite immunization in P. knowlesi rhesus monkeys confers protection and elicits sporozoite-specific memory T cells in the liver.

by Sathit Pichyangkul, Michele D Spring, Kosol Yongvanitchit, Utaiwan Kum-Arb, Amporn Limsalakpetch, Rawiwan Im-Erbsin, Ratawan Ubalee, Pattaraporn Vanachayangkul, Edmond J Remarque, Evelina Angov, Philip L Smith, David L Saunders
Published 2017-01-01

Transgene optimization, immunogenicity and in vitro efficacy of viral vectored vaccines expressing two alleles of Plasmodium falciparum AMA1.

by Sumi Biswas, Matthew D J Dicks, Carole A Long, Edmond J Remarque, Loredana Siani, Stefano Colloca, Matthew G Cottingham, Anthony A Holder, Sarah C Gilbert, Adrian V S Hill, Simon J Draper
Published 2011-01-01

Assay Harmonization and Use of Biological Standards To Improve the Reproducibility of the Hemagglutination Inhibition Assay: a FLUCOP Collaborative Study

by Joanna Waldock, Lingyi Zheng, Edmond J. Remarque, Alexandre Civet, Branda Hu, Sarah Lartey Jalloh, Rebecca Jane Cox, Sammy Ho, Katja Hoschler, Thierry Ollinger, Claudia Maria Trombetta, Othmar G. Engelhardt, Catherine Caillet
Published 2021-08-01

An experimental Staphylococcus aureus carriage and decolonization model in rhesus macaques (Macaca mulatta).

by Bibi C G C Slingerland, Merei Keehnen, Boudewijn Ouwerling, Mehri Tavakol, Susan V Snijders, Henri A Verbrugh, Margreet C Vos, Edmond J Remarque, Jan A M Langermans, Willem J B van Wamel
Published 2018-01-01

Pandemic Swine-Origin H1N1 Influenza Virus Replicates to Higher Levels and Induces More Fever and Acute Inflammatory Cytokines in Cynomolgus versus Rhesus Monkeys and Can Replicate...

by Petra Mooij, Gerrit Koopman, Daniëlla Mortier, Melanie van Heteren, Herman Oostermeijer, Zahra Fagrouch, Rudy de Laat, Gary Kobinger, Yan Li, Edmond J Remarque, Ivanela Kondova, Ernst J Verschoor, Willy M J M Bogers
Published 2015-01-01

Production, Quality Control, Stability and Pharmacotoxicity of a Malaria Vaccine Comprising Three Highly Similar PfAMA1 Protein Molecules to Overcome Antigenic Variation.

by Bart W Faber, Stephan Hellwig, Sophie Houard, Nicolas Havelange, Jürgen Drossard, Hubert Mertens, Alexander Croon, Robin Kastilan, Richard Byrne, Nicole van der Werff, Marjolein van der Eijk, Alan W Thomas, Clemens H M Kocken, Edmond J Remarque
Published 2016-01-01