Recognition Dynamics of Cancer Mutations on the ERp57-Tapasin Interface

by Monikaben Padariya, Umesh Kalathiya, Douglas R. Houston, Javier Antonio Alfaro
Published 2020-03-01

Structure- and ligand-based virtual screening identifies new scaffolds for inhibitors of the oncoprotein MDM2.

by Douglas R Houston, Li-Hsuan Yen, Simon Pettit, Malcolm D Walkinshaw
Published 2015-01-01

Design of drug-like hepsin inhibitors against prostate cancer and kidney stones

by Vincent Blay, Mu-Chun Li, Sunita P. Ho, Mashall L. Stoller, Hsing-Pang Hsieh, Douglas R. Houston
Published 2020-07-01

Lamin A molecular compression and sliding as mechanisms behind nucleoskeleton elasticity

by Alex A. Makarov, Juan Zou, Douglas R. Houston, Christos Spanos, Alexandra S. Solovyova, Cristina Cardenal-Peralta, Juri Rappsilber, Eric C. Schirmer
Published 2019-07-01

UFSRAT: Ultra-fast Shape Recognition with Atom Types--the discovery of novel bioactive small molecular scaffolds for FKBP12 and 11βHSD1.

by Steven Shave, Elizabeth A Blackburn, Jillian Adie, Douglas R Houston, Manfred Auer, Scott P Webster, Paul Taylor, Malcolm D Walkinshaw
Published 2015-01-01

Raf1 Is a DCAF for the Rik1 DDB1-like protein and has separable roles in siRNA generation and chromatin modification.

by Alessia Buscaino, Sharon A White, Douglas R Houston, Erwan Lejeune, Femke Simmer, Flavia de Lima Alves, Piyush T Diyora, Takeshi Urano, Elizabeth H Bayne, Juri Rappsilber, Robin C Allshire
Published 2012-02-01