From RNA World to SARS-CoV-2: The Edited Story of RNA Viral Evolution

by Zachary W. Kockler, Dmitry A. Gordenin
Published 2021-06-01

Suppression of allelic recombination and aneuploidy by cohesin is independent of Chk1 in Saccharomyces cerevisiae.

by Shay Covo, Eric Chiou, Dmitry A Gordenin, Michael A Resnick
Published 2014-01-01

Alkylation base damage is converted into repairable double-strand breaks and complex intermediates in G2 cells lacking AP endonuclease.

by Wenjian Ma, Jim W Westmoreland, Dmitry A Gordenin, Mike A Resnick
Published 2011-04-01

Cohesin Is limiting for the suppression of DNA damage-induced recombination between homologous chromosomes.

by Shay Covo, James W Westmoreland, Dmitry A Gordenin, Michael A Resnick
Published 2010-07-01

Hypermutability of damaged single-strand DNA formed at double-strand breaks and uncapped telomeres in yeast Saccharomyces cerevisiae.

by Yong Yang, Joan Sterling, Francesca Storici, Michael A Resnick, Dmitry A Gordenin
Published 2008-11-01

Similarity between mutation spectra in hypermutated genomes of rubella virus and in SARS-CoV-2 genomes accumulated during the COVID-19 pandemic.

by Leszek J Klimczak, Thomas A Randall, Natalie Saini, Jian-Liang Li, Dmitry A Gordenin
Published 2020-01-01

Base damage within single-strand DNA underlies in vivo hypermutability induced by a ubiquitous environmental agent.

by Kin Chan, Joan F Sterling, Steven A Roberts, Ashok S Bhagwat, Michael A Resnick, Dmitry A Gordenin
Published 2012-01-01

Similarity between mutation spectra in hypermutated genomes of rubella virus and in SARS-CoV-2 genomes accumulated during the COVID-19 pandemic

by Leszek J. Klimczak, Thomas A. Randall, Natalie Saini, Jian-Liang Li, Dmitry A. Gordenin, Sebastian D. Fugmann
Published 2020-01-01

Break-Induced Replication Is a Source of Mutation Clusters Underlying Kataegis

by Cynthia J. Sakofsky, Steven A. Roberts, Ewa Malc, Piotr A. Mieczkowski, Michael A. Resnick, Dmitry A. Gordenin, Anna Malkova
Published 2014-06-01

APOBEC-Induced Cancer Mutations Are Uniquely Enriched in Early-Replicating, Gene-Dense, and Active Chromatin Regions

by Marat D. Kazanov, Steven A. Roberts, Paz Polak, John Stamatoyannopoulos, Leszek J. Klimczak, Dmitry A. Gordenin, Shamil R. Sunyaev
Published 2015-11-01

Mutational signatures of redox stress in yeast single-strand DNA and of aging in human mitochondrial DNA share a common feature.

by Natalya P Degtyareva, Natalie Saini, Joan F Sterling, Victoria C Placentra, Leszek J Klimczak, Dmitry A Gordenin, Paul W Doetsch
Published 2019-05-01

Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation.

by Cynthia J Sakofsky, Natalie Saini, Leszek J Klimczak, Kin Chan, Ewa P Malc, Piotr A Mieczkowski, Adam B Burkholder, David Fargo, Dmitry A Gordenin
Published 2019-09-01

Correction: Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation.

by Cynthia J Sakofsky, Natalie Saini, Leszek J Klimczak, Kin Chan, Ewa P Malc, Piotr A Mieczkowski, Adam B Burkholder, David Fargo, Dmitry A Gordenin
Published 2020-03-01

UV-exposure, endogenous DNA damage, and DNA replication errors shape the spectra of genome changes in human skin.

by Natalie Saini, Camille K Giacobone, Leszek J Klimczak, Brian N Papas, Adam B Burkholder, Jian-Liang Li, David C Fargo, Re Bai, Kevin Gerrish, Cynthia L Innes, Shepherd H Schurman, Dmitry A Gordenin
Published 2021-01-01

Infectious vaccine-derived rubella viruses emerge, persist, and evolve in cutaneous granulomas of children with primary immunodeficiencies.

by Ludmila Perelygina, Min-Hsin Chen, Suganthi Suppiah, Adebola Adebayo, Emily Abernathy, Morna Dorsey, Lionel Bercovitch, Kenneth Paris, Kevin P White, Alfons Krol, Julie Dhossche, Ivan Y Torshin, Natalie Saini, Leszek J Klimczak, Dmitry A Gordenin, Andrey Zharkikh, Stanley Plotkin, Kathleen E Sullivan, Joseph Icenogle
Published 2019-10-01

The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts.

by Natalie Saini, Steven A Roberts, Leszek J Klimczak, Kin Chan, Sara A Grimm, Shuangshuang Dai, David C Fargo, Jayne C Boyer, William K Kaufmann, Jack A Taylor, Eunjung Lee, Isidro Cortes-Ciriano, Peter J Park, Shepherd H Schurman, Ewa P Malc, Piotr A Mieczkowski, Dmitry A Gordenin
Published 2016-10-01

Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways

by Hannah L. Klein, Giedrė Bačinskaja, Jun Che, Anais Cheblal, Rajula Elango, Anastasiya Epshtein, Devon M. Fitzgerald, Belén Gómez-González, Sharik R. Khan, Sandeep Kumar, Bryan A. Leland, Léa Marie, Qian Mei, Judith Miné-Hattab, Alicja Piotrowska, Erica J. Polleys, Christopher D. Putnam, Elina A. Radchenko, Anissia Ait Saada, Cynthia J. Sakofsky, Eun Yong Shim, Mathew Stracy, Jun Xia, Zhenxin Yan, Yi Yin, Andrés Aguilera, Juan Lucas Argueso, Catherine H. Freudenreich, Susan M. Gasser, Dmitry A. Gordenin, James E. Haber, Grzegorz Ira, Sue Jinks-Robertson, Megan C. King, Richard D. Kolodner, Andrei Kuzminov, Sarah AE Lambert, Sang Eun Lee, Kyle M. Miller, Sergei M. Mirkin, Thomas D. Petes, Susan M. Rosenberg, Rodney Rothstein, Lorraine S. Symington, Pawel Zawadzki, Nayun Kim, Michael Lisby, Anna Malkova
Published 2019-01-01