Recent advances in signal integration mechanisms in the unfolded protein response [version 1; peer review: 2 approved]

by G. Elif Karagöz, Tomás Aragón, Diego Acosta-Alvear
Published 2019-11-01

The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1

by Diego Acosta-Alvear, G Elif Karagöz, Florian Fröhlich, Han Li, Tobias C Walther, Peter Walter
Published 2018-12-01

An unfolded protein-induced conformational switch activates mammalian IRE1

by G Elif Karagöz, Diego Acosta-Alvear, Hieu T Nguyen, Crystal P Lee, Feixia Chu, Peter Walter
Published 2017-10-01

Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits

by Diego Acosta-Alvear, Min Y Cho, Thomas Wild, Tonia J Buchholz, Alana G Lerner, Olga Simakova, Jamie Hahn, Neha Korde, Ola Landgren, Irina Maric, Chunaram Choudhary, Peter Walter, Jonathan S Weissman, Martin Kampmann
Published 2015-09-01

Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic

by Aaron S Mendez, Jennifer Alfaro, Marisol A Morales-Soto, Arvin C Dar, Emma McCullagh, Katja Gotthardt, Han Li, Diego Acosta-Alvear, Carmela Sidrauski, Alexei V Korennykh, Sebastian Bernales, Kevan M Shokat, Peter Walter
Published 2015-05-01

Pharmacological brake-release of mRNA translation enhances cognitive memory

by Carmela Sidrauski, Diego Acosta-Alvear, Arkady Khoutorsky, Punitha Vedantham, Brian R Hearn, Han Li, Karine Gamache, Ciara M Gallagher, Kenny K-H Ang, Chris Wilson, Voytek Okreglak, Avi Ashkenazi, Byron Hann, Karim Nader, Michelle R Arkin, Adam R Renslo, Nahum Sonenberg, Peter Walter
Published 2013-05-01

Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response

by Estefanie Dufey, José Manuel Bravo-San Pedro, Cristian Eggers, Matías González-Quiroz, Hery Urra, Alfredo I. Sagredo, Denisse Sepulveda, Philippe Pihán, Amado Carreras-Sureda, Younis Hazari, Eduardo A. Sagredo, Daniela Gutierrez, Cristian Valls, Alexandra Papaioannou, Diego Acosta-Alvear, Gisela Campos, Pedro M. Domingos, Rémy Pedeux, Eric Chevet, Alejandra Alvarez, Patricio Godoy, Peter Walter, Alvaro Glavic, Guido Kroemer, Claudio Hetz
Published 2020-05-01