The proteasome inhibitor bortezomib induces an inhibitory chromatin environment at a distal enhancer of the estrogen receptor-α gene.

by Ginny L Powers, Prashant Rajbhandari, Natalia M Solodin, Brant Bickford, Elaine T Alarid
Published 2013-01-01

Inhibition of cholesterol biosynthesis through RNF145-dependent ubiquitination of SCAP

by Li Zhang, Prashant Rajbhandari, Christina Priest, Jaspreet Sandhu, Xiaohui Wu, Ryan Temel, Antonio Castrillo, Thomas Q de Aguiar Vallim, Tamer Sallam, Peter Tontonoz
Published 2017-10-01

NOTUM promotes thermogenic capacity and protects against diet-induced obesity in male mice

by Fangfei Guo, Marcus Seldin, Miklós Péterfy, Sarada Charugundla, Zhiqiang Zhou, Stephen D. Lee, Alice Mouton, Prashant Rajbhandari, Wenchao Zhang, Matteo Pellegrini, Peter Tontonoz, Aldons J. Lusis, Diana M. Shih
Published 2021-08-01

Noggin depletion in adipocytes promotes obesity in mice

by Ana M. Blázquez-Medela, Medet Jumabay, Prashant Rajbhandari, Tamer Sallam, Yina Guo, Jiayi Yao, Laurent Vergnes, Karen Reue, Li Zhang, Yucheng Yao, Alan M. Fogelman, Peter Tontonoz, Aldons J. Lusis, Xiuju Wu, Kristina I. Boström
Published 2019-07-01

Single cell analysis reveals immune cell–adipocyte crosstalk regulating the transcription of thermogenic adipocytes

by Prashant Rajbhandari, Douglas Arneson, Sydney K Hart, In Sook Ahn, Graciel Diamante, Luis C Santos, Nima Zaghari, An-Chieh Feng, Brandon J Thomas, Laurent Vergnes, Stephen D Lee, Abha K Rajbhandari, Karen Reue, Stephen T Smale, Xia Yang, Peter Tontonoz
Published 2019-10-01