Assessing the Accuracy of Quantitative Molecular Microbial Profiling

by Denise M. O'Sullivan, Thomas Laver, Sasithon Temisak, Nicholas Redshaw, Kathryn A. Harris, Carole A. Foy, David J. Studholme, Jim F. Huggett
Published 2014-11-01

Single base mutations in the nucleocapsid gene of SARS-CoV-2 affects amplification efficiency of sequence variants and may lead to assay failure

by Nathaniel Storey, Julianne R Brown, Rui P A Pereira, Denise M O'Sullivan, Jim F Huggett, Rachel Williams, Judith Breuer, Kathryn A Harris
Published 2021-09-01

Rapid detection of Mycobacterium tuberculosis by recombinase polymerase amplification.

by David S Boyle, Ruth McNerney, Hwee Teng Low, Brandon Troy Leader, Ailyn C Pérez-Osorio, Jessica C Meyer, Denise M O'Sullivan, David G Brooks, Olaf Piepenburg, Matthew S Forrest
Published 2014-01-01

Detection of Mycobacterium tuberculosis in sputum by gas chromatography-mass spectrometry of methyl mycocerosates released by thermochemolysis.

by Denise M O'Sullivan, Simona C Nicoara, Reggie Mutetwa, Stanley Mungofa, Oona Y-C Lee, David E Minnikin, Max W Bardwell, Elizabeth L Corbett, Ruth McNerney, Geraint H Morgan
Published 2012-01-01

Integrating informatics tools and portable sequencing technology for rapid detection of resistance to anti-tuberculous drugs

by Jody E. Phelan, Denise M. O’Sullivan, Diana Machado, Jorge Ramos, Yaa E. A. Oppong, Susana Campino, Justin O’Grady, Ruth McNerney, Martin L. Hibberd, Miguel Viveiros, Jim F. Huggett, Taane G. Clark
Published 2019-06-01

Elucidating emergence and transmission of multidrug-resistant tuberculosis in treatment experienced patients by whole genome sequencing.

by Taane G Clark, Kim Mallard, Francesc Coll, Mark Preston, Samuel Assefa, David Harris, Sam Ogwang, Francis Mumbowa, Bruce Kirenga, Denise M O'Sullivan, Alphonse Okwera, Kathleen D Eisenach, Moses Joloba, Stephen D Bentley, Jerrold J Ellner, Julian Parkhill, Edward C Jones-López, Ruth McNerney
Published 2013-01-01

An inter-laboratory study to investigate the impact of the bioinformatics component on microbiome analysis using mock communities

by Denise M. O’Sullivan, Ronan M. Doyle, Sasithon Temisak, Nicholas Redshaw, Alexandra S. Whale, Grace Logan, Jiabin Huang, Nicole Fischer, Gregory C. A. Amos, Mark D. Preston, Julian R. Marchesi, Josef Wagner, Julian Parkhill, Yair Motro, Hubert Denise, Robert D. Finn, Kathryn A. Harris, Gemma L. Kay, Justin O’Grady, Emma Ransom-Jones, Huihai Wu, Emma Laing, David J. Studholme, Ernest Diez Benavente, Jody Phelan, Taane G. Clark, Jacob Moran-Gilad, Jim F. Huggett
Published 2021-05-01