Robust validation of methylation levels association at CPT1A locus with lipid plasma levels1

by France Gagnon, Dylan Aïssi, Alain Carrié, Pierre-Emmanuel Morange, David-Alexandre Trégouët
Published 2014-07-01

miR-421 and miR-30c inhibit SERPINE 1 gene expression in human endothelial cells.

by Alexandre Marchand, Carole Proust, Pierre-Emmanuel Morange, Anne-Marie Lompré, David-Alexandre Trégouët
Published 2012-01-01

Design and Rationale of the ERA-CVD Consortium PREMED-CAD—Precision Medicine in Coronary Artery Disease

by Apurva Shrivastava, Vincenzo Marzolla, Henri Weidmann, Massimiliano Caprio, David-Alexandre Tregouet, Tanja Zeller, Mahir Karakas
Published 2020-01-01

A polymorphism in is associated with a lower risk for fatal cardiovascular events in females: the MORGAM project

by Ciara Vangjeli, Patrick Dicker, David-Alexandre Tregouet, Denis C Shields, Alun Evans, Alice V Stanton
Published 2011-12-01

Sex-specific effect of CPB2 Ala147Thr but not Thr325Ile variants on the risk of venous thrombosis: A comprehensive meta-analysis.

by Nora Zwingerman, Alejandra Medina-Rivera, Irfahan Kassam, Michael D Wilson, Pierre-Emmanuel Morange, David-Alexandre Trégouët, France Gagnon
Published 2017-01-01

Comparison of Cox Model Methods in A Low-dimensional Setting with Few Events

by Francisco M. Ojeda, Christian Müller, Daniela Börnigen, David-Alexandre Trégouët, Arne Schillert, Matthias Heinig, Tanja Zeller, Renate B. Schnabel
Published 2016-08-01

GENomE wide analysis of sotalol-induced IKr inhibition during ventricular REPOLarization, "GENEREPOL study": Lack of common variants with large effect sizes.

by Joe-Elie Salem, Marine Germain, Jean-Sébastien Hulot, Pascal Voiriot, Bruno Lebourgeois, Jean Waldura, David-Alexandre Tregouet, Beny Charbit, Christian Funck-Brentano
Published 2017-01-01

The choice of the filtering method in microarrays affects the inference regarding dosage compensation of the active X-chromosome.

by Raphaële Castagné, Maxime Rotival, Tanja Zeller, Philipp S Wild, Vinh Truong, David-Alexandre Trégouët, Thomas Munzel, Andreas Ziegler, François Cambien, Stefan Blankenberg, Laurence Tiret
Published 2011-01-01

Genome-wide investigation of DNA methylation marks associated with FV Leiden mutation.

by Dylan Aïssi, Jessica Dennis, Martin Ladouceur, Vinh Truong, Nora Zwingerman, Ares Rocanin-Arjo, Marine Germain, Tara A Paton, Pierre-Emmanuel Morange, France Gagnon, David-Alexandre Trégouët
Published 2014-01-01

Graphical modeling of gene expression in monocytes suggests molecular mechanisms explaining increased atherosclerosis in smokers.

by Ricardo A Verdugo, Tanja Zeller, Maxime Rotival, Philipp S Wild, Thomas Münzel, Karl J Lackner, Henri Weidmann, Ewa Ninio, David-Alexandre Trégouët, François Cambien, Stefan Blankenberg, Laurence Tiret
Published 2013-01-01

Preservation Analysis of Macrophage Gene Coexpression Between Human and Mouse Identifies PARK2 as a Genetically Controlled Master Regulator of Oxidative Phosphorylation in Humans

by Veronica Codoni, Yuna Blum, Mete Civelek, Carole Proust, Oscar Franzén, Cardiogenics Consortium, IDEM Leducq Consortium CADGenomics, Johan L. M. Björkegren, Wilfried Le Goff, Francois Cambien, Aldons J. Lusis, David-Alexandre Trégouët
Published 2016-10-01

Novel risk genes identified in a genome-wide association study for coronary artery disease in patients with type 1 diabetes

by Romain Charmet, Seamus Duffy, Sareh Keshavarzi, Beata Gyorgy, Michel Marre, Peter Rossing, Amy Jayne McKnight, Alexander P. Maxwell, Tarun veer Singh Ahluwalia, Andrew D. Paterson, David-Alexandre Trégouët, Samy Hadjadj
Published 2018-04-01

MFGE8 does not influence chorio-retinal homeostasis or choroidal neovascularization in vivo.

by William Raoul, Lucie Poupel, David-Alexandre Tregouet, Sophie Lavalette, Serge Camelo, Nicole Keller, Sophie Krumeich, Bertrand Calippe, Xavier Guillonneau, Francine Behar-Cohen, Salomon-Yves Cohen, Holger Baatz, Christophe Combadière, Clotilde Théry, Florian Sennlaub
Published 2012-01-01

Removing Batch Effects from Longitudinal Gene Expression - Quantile Normalization Plus ComBat as Best Approach for Microarray Transcriptome Data.

by Christian Müller, Arne Schillert, Caroline Röthemeier, David-Alexandre Trégouët, Carole Proust, Harald Binder, Norbert Pfeiffer, Manfred Beutel, Karl J Lackner, Renate B Schnabel, Laurence Tiret, Philipp S Wild, Stefan Blankenberg, Tanja Zeller, Andreas Ziegler
Published 2016-01-01

The EHA Research Roadmap: Blood Coagulation and Hemostatic Disorders

by Sabine Eichinger, Pierre E. Morange, Marco Cattaneo, Mathilde Fretigny, Antoine Rauch, Astrid van Hylckama Vlieg, David-Alexandre Trégouët, Wolfram Ruf, Marcel Levi, José A. Páramo, Tom van der Poll, Paul A. Kyrle, Isabella Garagiola, Flora Peyvandi
Published 2021-10-01

Shared genetic regulatory networks for cardiovascular disease and type 2 diabetes in multiple populations of diverse ethnicities in the United States.

by Le Shu, Kei Hang K Chan, Guanglin Zhang, Tianxiao Huan, Zeyneb Kurt, Yuqi Zhao, Veronica Codoni, David-Alexandre Trégouët, Cardiogenics Consortium, Jun Yang, James G Wilson, Xi Luo, Daniel Levy, Aldons J Lusis, Simin Liu, Xia Yang
Published 2017-09-01

A rare coding mutation in the MAST2 gene causes venous thrombosis in a French family with unexplained thrombophilia: The Breizh MAST2 Arg89Gln variant.

by Pierre-Emmanuel Morange, Franck Peiretti, Lenaick Gourhant, Carole Proust, Omar Soukarieh, Anne-Sophie Pulcrano-Nicolas, Ganapathi-Varma Saripella, Luca Stefanucci, Romaric Lacroix, Manal Ibrahim-Kosta, Catherine A Lemarié, Mattia Frontini, Marie-Christine Alessi, David-Alexandre Trégouët, Francis Couturaud
Published 2021-01-01

Caution in interpreting results from imputation analysis when linkage disequilibrium extends over a large distance: a case study on venous thrombosis.

by Marine Germain, Noémie Saut, Tiphaine Oudot-Mellakh, Luc Letenneur, Anne-Marie Dupuy, Marion Bertrand, Marie-Christine Alessi, Jean-Charles Lambert, Diana Zelenika, Joseph Emmerich, Laurence Tiret, Francois Cambien, Mark Lathrop, Philippe Amouyel, Pierre-Emmanuel Morange, David-Alexandre Trégouët
Published 2012-01-01

An artificial neural network approach integrating plasma proteomics and genetic data identifies PLXNA4 as a new susceptibility locus for pulmonary embolism

by Misbah Razzaq, Maria Jesus Iglesias, Manal Ibrahim-Kosta, Louisa Goumidi, Omar Soukarieh, Carole Proust, Maguelonne Roux, Pierre Suchon, Anne Boland, Delphine Daiain, Robert Olaso, Sebastian Havervall, Charlotte Thalin, Lynn Butler, Jean-François Deleuze, Jacob Odeberg, Pierre-Emmanuel Morange, David-Alexandre Trégouët
Published 2021-07-01

Correction: Comprehensive Exploration of the Effects of miRNA SNPs on Monocyte Gene Expression.

by Nicolas Greliche, Tanja Zeller, Philipp S. Wild, Maxime Rotival, Arne Schillert, Andreas Ziegler, Panos Deloukas, Jeanette Erdmann, Christian Hengstenberg, Willem H. Ouwehand, Nilesh J. Samani, Heribert Schunkert, Thomas Munzel, Karl J. Lackner, François Cambien, Alison H. Goodall, Laurence Tiret, Stefan Blankenberg, David-Alexandre Trégouët
Published 2012-01-01