miR-421 and miR-30c inhibit SERPINE 1 gene expression in human endothelial cells.

by Alexandre Marchand, Carole Proust, Pierre-Emmanuel Morange, Anne-Marie Lompré, David-Alexandre Trégouët
Published 2012-01-01

Preservation Analysis of Macrophage Gene Coexpression Between Human and Mouse Identifies PARK2 as a Genetically Controlled Master Regulator of Oxidative Phosphorylation in Humans

by Veronica Codoni, Yuna Blum, Mete Civelek, Carole Proust, Oscar Franzén, Cardiogenics Consortium, IDEM Leducq Consortium CADGenomics, Johan L. M. Björkegren, Wilfried Le Goff, Francois Cambien, Aldons J. Lusis, David-Alexandre Trégouët
Published 2016-10-01

Removing Batch Effects from Longitudinal Gene Expression - Quantile Normalization Plus ComBat as Best Approach for Microarray Transcriptome Data.

by Christian Müller, Arne Schillert, Caroline Röthemeier, David-Alexandre Trégouët, Carole Proust, Harald Binder, Norbert Pfeiffer, Manfred Beutel, Karl J Lackner, Renate B Schnabel, Laurence Tiret, Philipp S Wild, Stefan Blankenberg, Tanja Zeller, Andreas Ziegler
Published 2016-01-01

A rare coding mutation in the MAST2 gene causes venous thrombosis in a French family with unexplained thrombophilia: The Breizh MAST2 Arg89Gln variant.

by Pierre-Emmanuel Morange, Franck Peiretti, Lenaick Gourhant, Carole Proust, Omar Soukarieh, Anne-Sophie Pulcrano-Nicolas, Ganapathi-Varma Saripella, Luca Stefanucci, Romaric Lacroix, Manal Ibrahim-Kosta, Catherine A Lemarié, Mattia Frontini, Marie-Christine Alessi, David-Alexandre Trégouët, Francis Couturaud
Published 2021-01-01

An artificial neural network approach integrating plasma proteomics and genetic data identifies PLXNA4 as a new susceptibility locus for pulmonary embolism

by Misbah Razzaq, Maria Jesus Iglesias, Manal Ibrahim-Kosta, Louisa Goumidi, Omar Soukarieh, Carole Proust, Maguelonne Roux, Pierre Suchon, Anne Boland, Delphine Daiain, Robert Olaso, Sebastian Havervall, Charlotte Thalin, Lynn Butler, Jean-François Deleuze, Jacob Odeberg, Pierre-Emmanuel Morange, David-Alexandre Trégouët
Published 2021-07-01

Genetics and beyond--the transcriptome of human monocytes and disease susceptibility.

by Tanja Zeller, Philipp Wild, Silke Szymczak, Maxime Rotival, Arne Schillert, Raphaele Castagne, Seraya Maouche, Marine Germain, Karl Lackner, Heidi Rossmann, Medea Eleftheriadis, Christoph R Sinning, Renate B Schnabel, Edith Lubos, Detlev Mennerich, Werner Rust, Claire Perret, Carole Proust, Viviane Nicaud, Joseph Loscalzo, Norbert Hübner, David Tregouet, Thomas Münzel, Andreas Ziegler, Laurence Tiret, Stefan Blankenberg, François Cambien
Published 2010-01-01

Powerful identification of cis-regulatory SNPs in human primary monocytes using allele-specific gene expression.

by Jonas Carlsson Almlöf, Per Lundmark, Anders Lundmark, Bing Ge, Seraya Maouche, Harald H H Göring, Ulrika Liljedahl, Camilla Enström, Jessy Brocheton, Carole Proust, Tiphaine Godefroy, Jennifer G Sambrook, Jennifer Jolley, Abigail Crisp-Hihn, Nicola Foad, Heather Lloyd-Jones, Jonathan Stephens, Rhian Gwilliam, Catherine M Rice, Christian Hengstenberg, Nilesh J Samani, Jeanette Erdmann, Heribert Schunkert, Tomi Pastinen, Panos Deloukas, Alison H Goodall, Willem H Ouwehand, François Cambien, Ann-Christine Syvänen
Published 2012-01-01

Integrating genome-wide genetic variations and monocyte expression data reveals trans-regulated gene modules in humans.

by Maxime Rotival, Tanja Zeller, Philipp S Wild, Seraya Maouche, Silke Szymczak, Arne Schillert, Raphaele Castagné, Arne Deiseroth, Carole Proust, Jessy Brocheton, Tiphaine Godefroy, Claire Perret, Marine Germain, Medea Eleftheriadis, Christoph R Sinning, Renate B Schnabel, Edith Lubos, Karl J Lackner, Heidi Rossmann, Thomas Münzel, Augusto Rendon, Cardiogenics Consortium, Jeanette Erdmann, Panos Deloukas, Christian Hengstenberg, Patrick Diemert, Gilles Montalescot, Willem H Ouwehand, Nilesh J Samani, Heribert Schunkert, David-Alexandre Tregouet, Andreas Ziegler, Alison H Goodall, François Cambien, Laurence Tiret, Stefan Blankenberg
Published 2011-12-01

Correction: Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy.

by Ulrike Esslinger, Sophie Garnier, Agathe Korniat, Carole Proust, Georgios Kararigas, Martina Müller-Nurasyid, Jean-Philippe Empana, Michael P Morley, Claire Perret, Klaus Stark, Alexander G Bick, Sanjay K Prasad, Jennifer Kriebel, Jin Li, Laurence Tiret, Konstantin Strauch, Declan P O'Regan, Kenneth B Marguiles, Jonathan G Seidman, Pierre Boutouyrie, Patrick Lacolley, Xavier Jouven, Christian Hengstenberg, Michel Komajda, Hakon Hakonarson, Richard Isnard, Eloisa Arbustini, Harald Grallert, Stuart A Cook, Christine E Seidman, Vera Regitz-Zagrosek, Thomas P Cappola, Philippe Charron, François Cambien, Eric Villard
Published 2020-01-01

Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy.

by Ulrike Esslinger, Sophie Garnier, Agathe Korniat, Carole Proust, Georgios Kararigas, Martina Müller-Nurasyid, Jean-Philippe Empana, Michael P Morley, Claire Perret, Klaus Stark, Alexander G Bick, Sanjay K Prasad, Jennifer Kriebel, Jin Li, Laurence Tiret, Konstantin Strauch, Declan P O'Regan, Kenneth B Marguiles, Jonathan G Seidman, Pierre Boutouyrie, Patrick Lacolley, Xavier Jouven, Christian Hengstenberg, Michel Komajda, Hakon Hakonarson, Richard Isnard, Eloisa Arbustini, Harald Grallert, Stuart A Cook, Christine E Seidman, Vera Regitz-Zagrosek, Thomas P Cappola, Philippe Charron, François Cambien, Eric Villard
Published 2017-01-01