The Snail transcription factor regulates the numbers of neural precursor cells and newborn neurons throughout mammalian life.

by Mark A Zander, Gonzalo I Cancino, Thomas Gridley, David R Kaplan, Freda D Miller
Published 2014-01-01

Metformin Acts on Two Different Molecular Pathways to Enhance Adult Neural Precursor Proliferation/Self-Renewal and Differentiation

by Michael Fatt, Karolynn Hsu, Ling He, Fredric Wondisford, Freda D. Miller, David R. Kaplan, Jing Wang
Published 2015-12-01

Interleukin-6 Regulates Adult Neural Stem Cell Numbers during Normal and Abnormal Post-natal Development

by Mekayla A. Storer, Denis Gallagher, Michael P. Fatt, Jaclin V. Simonetta, David R. Kaplan, Freda D. Miller
Published 2018-05-01

Single-Cell Profiling Shows Murine Forebrain Neural Stem Cells Reacquire a Developmental State when Activated for Adult Neurogenesis

by Michael J. Borrett, Brendan T. Innes, Danielle Jeong, Nareh Tahmasian, Mekayla A. Storer, Gary D. Bader, David R. Kaplan, Freda D. Miller
Published 2020-08-01

Developmental Emergence of Adult Neural Stem Cells as Revealed by Single-Cell Transcriptional Profiling

by Scott A. Yuzwa, Michael J. Borrett, Brendan T. Innes, Anastassia Voronova, Troy Ketela, David R. Kaplan, Gary D. Bader, Freda D. Miller
Published 2017-12-01

A Glo1-Methylglyoxal Pathway that Is Perturbed in Maternal Diabetes Regulates Embryonic and Adult Neural Stem Cell Pools in Murine Offspring

by Guang Yang, Gonzalo I. Cancino, Siraj K. Zahr, Axel Guskjolen, Anastassia Voronova, Denis Gallagher, Paul W. Frankland, David R. Kaplan, Freda D. Miller
Published 2016-10-01

In Vivo Antitumor and Antimetastatic Activity of Sunitinib in Preclinical Neuroblastoma Mouse Model

by Libo Zhang, Kristen M. Smith, Amy Lee Chong, Diana Stempak, Herman Yeger, Paula Marrano, Paul S. Thorner, Meredith S. Irwin, David R. Kaplan, Sylvain Baruchel
Published 2009-05-01

Methylglyoxal couples metabolic and translational control of Notch signalling in mammalian neural stem cells

by Deivid Carvalho Rodrigues, Emily M. Harvey, Rejitha Suraj, Sarah L. Erickson, Lamees Mohammad, Mengli Ren, Hongrui Liu, Guiqiong He, David R. Kaplan, James Ellis, Guang Yang
Published 2020-04-01

Identification of Drugs that Regulate Dermal Stem Cells and Enhance Skin Repair

by Sibel Naska, Scott A. Yuzwa, Adam P.W. Johnston, Smitha Paul, Kristen M. Smith, Maryline Paris, Michael V. Sefton, Alessandro Datti, Freda D. Miller, David R. Kaplan
Published 2016-01-01

The Protein Tyrosine Phosphatase Receptor Delta Regulates Developmental Neurogenesis

by Hideaki Tomita, Francisca Cornejo, Begoña Aranda-Pino, Cameron L. Woodard, Constanza C. Rioseco, Benjamin G. Neel, Alejandra R. Alvarez, David R. Kaplan, Freda D. Miller, Gonzalo I. Cancino
Published 2020-01-01

The DEAD-box helicase DDX56 is a conserved stemness regulator in normal and cancer stem cells

by Michael Pryszlak, Mallory Wiggans, Xin Chen, Julia E. Jaramillo, Sarah E. Burns, Laura M. Richards, Trevor J. Pugh, David R. Kaplan, Xi Huang, Peter B. Dirks, Bret J. Pearson
Published 2021-03-01

Direct Genesis of Functional Rodent and Human Schwann Cells from Skin Mesenchymal Precursors

by Matthew P. Krause, Shaalee Dworski, Konstantin Feinberg, Karen Jones, Adam P.W. Johnston, Smitha Paul, Maryline Paris, Elior Peles, Darius Bagli, Christopher R. Forrest, David R. Kaplan, Freda D. Miller
Published 2014-07-01

Radioligands for Tropomyosin Receptor Kinase (Trk) Positron Emission Tomography Imaging

by Ralf Schirrmacher, Justin J. Bailey, Andrew V. Mossine, Peter J. H. Scott, Lena Kaiser, Peter Bartenstein, Simon Lindner, David R. Kaplan, Alexey Kostikov, Gert Fricker, Anne Mahringer, Pedro Rosa-Neto, Esther Schirrmacher, Carmen Wängler, Björn Wängler, Alexander Thiel, Jean-Paul Soucy, Vadim Bernard-Gauthier
Published 2019-01-01

ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenografts.

by Alice L Yuan, Christian B Ricks, Alexandra K Bohm, Xueqing Lun, Lori Maxwell, Shahana Safdar, Shazreh Bukhari, Amanda Gerber, Wajid Sayeed, Elizabeth A Bering, Haley Pedersen, Jennifer A Chan, Yaoqing Shen, Marco Marra, David R Kaplan, Warren Mason, Lindsey D Goodman, Ravesanker Ezhilarasan, Ascher B Kaufmann, Matthew Cabral, Steve M Robbins, Donna L Senger, Daniel P Cahill, Erik P Sulman, J Gregory Cairncross, Michael D Blough
Published 2018-01-01

Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression

by Astrid De Boeck, Bo Young Ahn, Charlotte D’Mello, Xueqing Lun, Shyam V. Menon, Mana M. Alshehri, Frank Szulzewsky, Yaoqing Shen, Lubaba Khan, Ngoc Ha Dang, Elliott Reichardt, Kimberly-Ann Goring, Jennifer King, Cameron J. Grisdale, Natalie Grinshtein, Dolores Hambardzumyan, Karlyne M. Reilly, Michael D. Blough, J. Gregory Cairncross, V. Wee Yong, Marco A. Marra, Steven J. M. Jones, David R. Kaplan, Kathy D. McCoy, Eric C. Holland, Pinaki Bose, Jennifer A. Chan, Stephen M. Robbins, Donna L. Senger
Published 2020-10-01