Global transcriptome analysis of T-competent progenitors in the bone marrow

by Vionnie W.C. Yu, David T. Scadden
Published 2015-09-01

Single Targeted Exon Mutation Creates a True Congenic Mouse for Competitive Hematopoietic Stem Cell Transplantation: The C57BL/6-CD45.1STEM Mouse

by Francois E. Mercier, David B. Sykes, David T. Scadden
Published 2016-06-01

Transcriptome comparison of distinct osteolineage subsets in the hematopoietic stem cell niche using a triple fluorescent transgenic mouse model

by Vionnie W.C. Yu, Stefania Lymperi, Francesca Ferraro, David T. Scadden
Published 2015-09-01

dropEst: pipeline for accurate estimation of molecular counts in droplet-based single-cell RNA-seq experiments

by Viktor Petukhov, Jimin Guo, Ninib Baryawno, Nicolas Severe, David T. Scadden, Maria G. Samsonova, Peter V. Kharchenko
Published 2018-06-01

SIRT3 Reverses Aging-Associated Degeneration

by Katharine Brown, Stephanie Xie, Xiaolei Qiu, Mary Mohrin, Jiyung Shin, Yufei Liu, Dan Zhang, David T. Scadden, Danica Chen
Published 2013-02-01

Distinctive Mesenchymal-Parenchymal Cell Pairings Govern B Cell Differentiation in the Bone Marrow

by Vionnie W.C. Yu, Stefania Lymperi, Toshihiko Oki, Alexandra Jones, Peter Swiatek, Radovan Vasic, Francesca Ferraro, David T. Scadden
Published 2016-08-01

Transmembrane Inhibitor of RICTOR/mTORC2 in Hematopoietic Progenitors

by Dongjun Lee, Stephen M. Sykes, Demetrios Kalaitzidis, Andrew A. Lane, Youmna Kfoury, Marc H.G.P. Raaijmakers, Ying-Hua Wang, Scott A. Armstrong, David T. Scadden
Published 2014-11-01

Correction: Tracking Single Cells in Live Animals Using a Photoconvertible Near-Infrared Cell Membrane Label

by Alicia L. Carlson, Joji Fujisaki, Juwell Wu, Judith M. Runnels, Raphaël Turcotte, Joel A. Spencer, Cristina Lo Celso, David T. Scadden, Terry B. Strom, Charles P. Lin
Published 2013-01-01

Correction: Tracking Single Cells in Live Animals Using a Photoconvertible Near-Infrared Cell Membrane Label.

by Alicia L. Carlson, Joji Fujisaki, Juwell Wu, Judith M. Runnels, Raphaël Turcotte, Joel A. Spencer, Cristina Lo Celso, David T. Scadden, Terry B. Strom, Charles P. Lin
Published 2013-01-01

Tracking single cells in live animals using a photoconvertible near-infrared cell membrane label.

by Alicia L Carlson, Joji Fujisaki, Juwell Wu, Judith M Runnels, Raphaël Turcotte, Joel A Spencer, Cristina Lo Celso, David T Scadden, Terry B Strom, Charles P Lin
Published 2013-01-01

Effective Multi-lineage Engraftment in a Mouse Model of Fanconi Anemia Using Non-genotoxic Antibody-Based Conditioning

by Meera A. Srikanthan, Olivier Humbert, Kevin G. Haworth, Christina Ironside, Yogendra S. Rajawat, Bruce R. Blazar, Rahul Palchaudhuri, Anthony E. Boitano, Michael P. Cooke, David T. Scadden, Hans-Peter Kiem
Published 2020-06-01

Imaging dynamic mTORC1 pathway activity in vivo reveals marked shifts that support time-specific inhibitor therapy in AML

by Toshihiko Oki, Francois Mercier, Hiroki Kato, Yookyung Jung, Thomas O. McDonald, Joel A. Spencer, Michael C. Mazzola, Nick van Gastel, Charles P. Lin, Franziska Michor, Toshio Kitamura, David T. Scadden
Published 2021-01-01

Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation

by Agnieszka Czechowicz, Rahul Palchaudhuri, Amelia Scheck, Yu Hu, Jonathan Hoggatt, Borja Saez, Wendy W. Pang, Michael K. Mansour, Tiffany A. Tate, Yan Yi Chan, Emily Walck, Gerlinde Wernig, Judith A. Shizuru, Florian Winau, David T. Scadden, Derrick J. Rossi
Published 2019-02-01

A point mutation in the Ncr1 signal peptide impairs the development of innate lymphoid cell subsets

by Francisca F. Almeida, Sara Tognarelli, Antoine Marçais, Andrew J. Kueh, Miriam E. Friede, Yang Liao, Simon N. Willis, Kylie Luong, Fabrice Faure, Francois E. Mercier, Justine Galluso, Matthew Firth, Emilie Narni-Mancinelli, Bushra Rais, David T. Scadden, Francesco Spallotta, Sandra Weil, Ariane Giannattasio, Franziska Kalensee, Tobias Zöller, Nicholas D. Huntington, Ulrike Schleicher, Andreas G. Chiocchetti, Sophie Ugolini, Marco J. Herold, Wei Shi, Joachim Koch, Alexander Steinle, Eric Vivier, Thierry Walzer, Gabrielle T. Belz, Evelyn Ullrich
Published 2018-10-01

Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with Improved Selectivity over Hematopoietic Progenitors

by Shrikanta Chattopadhyay, Alison L. Stewart, Siddhartha Mukherjee, Cherrie Huang, Kimberly A. Hartwell, Peter G. Miller, Radhika Subramanian, Leigh C. Carmody, Rushdia Z. Yusuf, David B. Sykes, Joshiawa Paulk, Amedeo Vetere, Sonia Vallet, Loredana Santo, Diana D. Cirstea, Teru Hideshima, Vlado Dančík, Max M. Majireck, Mahmud M. Hussain, Shambhavi Singh, Ryan Quiroz, Jonathan Iaconelli, Rakesh Karmacharya, Nicola J. Tolliday, Paul A. Clemons, Malcolm A.S. Moore, Andrew M. Stern, Alykhan F. Shamji, Benjamin L. Ebert, Todd R. Golub, Noopur S. Raje, David T. Scadden, Stuart L. Schreiber
Published 2015-02-01