DNA-launched RNA replicon vaccines induce potent anti-SARS-CoV-2 immune responses in mice

by Inga Szurgot, Leo Hanke, Daniel J. Sheward, Laura Perez Vidakovics, Ben Murrell, Gerald M. McInerney, Peter Liljeström
Published 2021-02-01

Picomolar SARS-CoV-2 Neutralization UsingMulti-Arm PEG Nanobody Constructs

by Ainhoa Moliner-Morro, Daniel J. Sheward, Vivien Karl, Laura Perez Vidakovics, Ben Murrell, Gerald M. McInerney, Leo Hanke
Published 2020-12-01

Adjuvanted SARS-CoV-2 spike protein elicits neutralizing antibodies and CD4 T cell responses after a single immunization in mice

by Katharina Wørzner, Daniel J. Sheward, Signe Tandrup Schmidt, Leo Hanke, Julie Zimmermann, Gerald McInerney, Gunilla B. Karlsson Hedestam, Ben Murrell, Dennis Christensen, Gabriel Kristian Pedersen
Published 2021-01-01

An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction

by Leo Hanke, Laura Vidakovics Perez, Daniel J. Sheward, Hrishikesh Das, Tim Schulte, Ainhoa Moliner-Morro, Martin Corcoran, Adnane Achour, Gunilla B. Karlsson Hedestam, B. Martin Hällberg, Ben Murrell, Gerald M. McInerney
Published 2020-09-01

SARS-CoV-2 protein subunit vaccination of mice and rhesus macaques elicits potent and durable neutralizing antibody responses

by Marco Mandolesi, Daniel J. Sheward, Leo Hanke, Junjie Ma, Pradeepa Pushparaj, Laura Perez Vidakovics, Changil Kim, Monika Àdori, Klara Lenart, Karin Loré, Xaquin Castro Dopico, Jonathan M. Coquet, Gerald M. McInerney, Gunilla B. Karlsson Hedestam, Ben Murrell
Published 2021-04-01

Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2

by Tânia F. Custódio, Hrishikesh Das, Daniel J. Sheward, Leo Hanke, Samuel Pazicky, Joanna Pieprzyk, Michèle Sorgenfrei, Martin A. Schroer, Andrey Yu. Gruzinov, Cy M. Jeffries, Melissa A. Graewert, Dmitri I. Svergun, Nikolay Dobrev, Kim Remans, Markus A. Seeger, Gerald M. McInerney, Ben Murrell, B. Martin Hällberg, Christian Löw
Published 2020-11-01

Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape.

by Constantinos Kurt Wibmer, Jason Gorman, Gabriel Ozorowski, Jinal N Bhiman, Daniel J Sheward, Debra H Elliott, Julie Rouelle, Ashley Smira, M Gordon Joyce, Nonkululeko Ndabambi, Aliaksandr Druz, Mangai Asokan, Mangai Asokan, Dennis R Burton, Mark Connors, Salim S Abdool Karim, John R Mascola, James E Robinson, Andrew B Ward, Carolyn Williamson, Peter D Kwong, Lynn Morris, Penny L Moore
Published 2017-01-01

Correction: Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization.

by Cecilia Rademeyer, Bette Korber, Michael S Seaman, Elena E Giorgi, Ruwayhida Thebus, Alexander Robles, Daniel J Sheward, Kshitij Wagh, Jetta Garrity, Brittany R Carey, Hongmei Gao, Kelli M Greene, Haili Tang, Gama P Bandawe, Jinny C Marais, Thabo E Diphoko, Peter Hraber, Nancy Tumba, Penny L Moore, Glenda E Gray, James Kublin, M Juliana McElrath, Marion Vermeulen, Keren Middelkoop, Linda-Gail Bekker, Michael Hoelscher, Leonard Maboko, Joseph Makhema, Merlin L Robb, Salim Abdool Karim, Quarraisha Abdool Karim, Jerome H Kim, Beatrice H Hahn, Feng Gao, Ronald Swanstrom, Lynn Morris, David C Montefiori, Carolyn Williamson
Published 2017-09-01

Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization.

by Cecilia Rademeyer, Bette Korber, Michael S Seaman, Elena E Giorgi, Ruwayhida Thebus, Alexander Robles, Daniel J Sheward, Kshitij Wagh, Jetta Garrity, Brittany R Carey, Hongmei Gao, Kelli M Greene, Haili Tang, Gama P Bandawe, Jinny C Marais, Thabo E Diphoko, Peter Hraber, Nancy Tumba, Penny L Moore, Glenda E Gray, James Kublin, M Juliana McElrath, Marion Vermeulen, Keren Middelkoop, Linda-Gail Bekker, Michael Hoelscher, Leonard Maboko, Joseph Makhema, Merlin L Robb, Salim Abdool Karim, Quarraisha Abdool Karim, Jerome H Kim, Beatrice H Hahn, Feng Gao, Ronald Swanstrom, Lynn Morris, David C Montefiori, Carolyn Williamson
Published 2016-07-01