Modulating the endoplasmic reticulum stress response attenuates neurodegeneration in a Caenorhabditis elegans model of spinal muscular atrophy

by James J. Doyle, Celine Vrancx, Claudia Maios, Audrey Labarre, Shunmoogum A. Patten, J. Alex Parker
Published 2020-12-01

Methylene blue protects against TDP-43 and FUS neuronal toxicity in C. elegans and D. rerio.

by Alexandra Vaccaro, Shunmoogum A Patten, Sorana Ciura, Claudia Maios, Martine Therrien, Pierre Drapeau, Edor Kabashi, J Alex Parker
Published 2012-01-01

Pharmacological reduction of ER stress protects against TDP-43 neuronal toxicity in vivo

by Alexandra Vaccaro, Shunmoogum A. Patten, Dina Aggad, Carl Julien, Claudia Maios, Edor Kabashi, Pierre Drapeau, J. Alex Parker
Published 2013-07-01

RNA-Based Therapy Utilizing Oculopharyngeal Muscular Dystrophy Transcript Knockdown and Replacement

by Aida Abu-Baker, Nawwaf Kharma, Jonathan Perreault, Alanna Grant, Masoud Shekarabi, Claudia Maios, Michele Dona, Christian Neri, Patrick A. Dion, Alex Parker, Luc Varin, Guy A. Rouleau
Published 2019-04-01