Stochastic priming and spatial cues orchestrate heterogeneous clonal contribution to mouse pancreas organogenesis

by Hjalte List Larsen, Laura Martín-Coll, Alexander Valentin Nielsen, Christopher V. E. Wright, Ala Trusina, Yung Hae Kim, Anne Grapin-Botton
Published 2017-09-01

Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and β-Cell Function

by Kathryn D. Henley, Diana E. Stanescu, Peter A. Kropp, Christopher V.E. Wright, Kyoung-Jae Won, Doris A. Stoffers, Maureen Gannon
Published 2016-06-01

PDX1 Binds and Represses Hepatic Genes to Ensure Robust Pancreatic Commitment in Differentiating Human Embryonic Stem Cells

by Adrian Kee Keong Teo, Norihiro Tsuneyoshi, Shawn Hoon, Ee Kim Tan, Lawrence W. Stanton, Christopher V.E. Wright, N. Ray Dunn
Published 2015-04-01

Myeloid Cell-Derived HB-EGF Drives Tissue Recovery After PancreatitisSummary

by Hui-Ju Wen, Shan Gao, Yin Wang, Michael Ray, Mark A. Magnuson, Christopher V.E. Wright, Marina Pasca Di Magliano, Timothy L. Frankel, Howard C. Crawford
Published 2019-01-01

Foxl1-Expressing Mesenchymal Cells Constitute the Intestinal Stem Cell NicheSummary

by Reina Aoki, Michal Shoshkes-Carmel, Nan Gao, Soona Shin, Catherine L. May, Maria L. Golson, Adam M. Zahm, Michael Ray, Caroline L. Wiser, Christopher V.E. Wright, Klaus H. Kaestner
Published 2016-03-01

A Role for Dystonia-Associated Genes in Spinal GABAergic Interneuron Circuitry

by Juliet Zhang, Jarret A.P. Weinrich, Jeffrey B. Russ, John D. Comer, Praveen K. Bommareddy, Richard J. DiCasoli, Christopher V.E. Wright, Yuqing Li, Peter J. van Roessel, Julia A. Kaltschmidt
Published 2017-10-01

Point mutations in the PDX1 transactivation domain impair human β-cell development and function

by Xianming Wang, Michael Sterr, Ansarullah, Ingo Burtscher, Anika Böttcher, Julia Beckenbauer, Johanna Siehler, Thomas Meitinger, Hans-Ulrich Häring, Harald Staiger, Filippo M. Cernilogar, Gunnar Schotta, Martin Irmler, Johannes Beckers, Christopher V.E. Wright, Mostafa Bakhti, Heiko Lickert
Published 2019-06-01

Sensory and spinal inhibitory dorsal midline crossing is independent of Robo3

by John Daniel Comer, John Daniel Comer, John Daniel Comer, Fong Cheng ePan, Spencer G. Willet, Parthiv eHaldipur, Kathleen eMillen, Kathleen eMillen, Christopher V.E. Wright, Julia A. Kaltschmidt, Julia A. Kaltschmidt, Julia A. Kaltschmidt
Published 2015-07-01

Genome-wide analysis of PDX1 target genes in human pancreatic progenitors

by Xianming Wang, Michael Sterr, Ingo Burtscher, Shen Chen, Anja Hieronimus, Fausto Machicao, Harald Staiger, Hans-Ulrich Häring, Gabriele Lederer, Thomas Meitinger, Filippo M. Cernilogar, Gunnar Schotta, Martin Irmler, Johannes Beckers, Martin Hrabě de Angelis, Michael Ray, Christopher V.E. Wright, Mostafa Bakhti, Heiko Lickert
Published 2018-03-01