Hydrophobic fluorescent probes introduce artifacts into single molecule tracking experiments due to non-specific binding.

by Laura C Zanetti-Domingues, Christopher J Tynan, Daniel J Rolfe, David T Clarke, Marisa Martin-Fernandez
Published 2013-01-01

Multicolour single molecule imaging in cells with near infra-red dyes.

by Christopher J Tynan, David T Clarke, Benjamin C Coles, Daniel J Rolfe, Marisa L Martin-Fernandez, Stephen E D Webb
Published 2012-01-01

3D visualization of additive occlusion and tunable full-spectrum fluorescence in calcite

by David C. Green, Johannes Ihli, Paul D. Thornton, Mark A. Holden, Bartosz Marzec, Yi-Yeoun Kim, Alex N. Kulak, Mark A. Levenstein, Chiu Tang, Christophe Lynch, Stephen E. D. Webb, Christopher J. Tynan, Fiona C. Meldrum
Published 2016-11-01

Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor

by Jemima Ho, Xuexin Yang, Spyridoula-Angeliki Nikou, Nessim Kichik, Andrew Donkin, Nicole O. Ponde, Jonathan P. Richardson, Remi L. Gratacap, Linda S. Archambault, Christian P. Zwirner, Celia Murciano, Rhonda Henley-Smith, Selvam Thavaraj, Christopher J. Tynan, Sarah L. Gaffen, Bernhard Hube, Robert T. Wheeler, David L. Moyes, Julian R. Naglik
Published 2019-05-01

EGFR oligomerization organizes kinase-active dimers into competent signalling platforms

by Sarah R. Needham, Selene K. Roberts, Anton Arkhipov, Venkatesh P. Mysore, Christopher J. Tynan, Laura C. Zanetti-Domingues, Eric T. Kim, Valeria Losasso, Dimitrios Korovesis, Michael Hirsch, Daniel J. Rolfe, David T. Clarke, Martyn D. Winn, Alireza Lajevardipour, Andrew H. A. Clayton, Linda J. Pike, Michela Perani, Peter J. Parker, Yibing Shan, David E. Shaw, Marisa L. Martin-Fernandez
Published 2016-10-01

The architecture of EGFR’s basal complexes reveals autoinhibition mechanisms in dimers and oligomers

by Laura C. Zanetti-Domingues, Dimitrios Korovesis, Sarah R. Needham, Christopher J. Tynan, Shiori Sagawa, Selene K. Roberts, Antonija Kuzmanic, Elena Ortiz-Zapater, Purvi Jain, Rob C. Roovers, Alireza Lajevardipour, Paul M. P. van Bergen en Henegouwen, George Santis, Andrew H. A. Clayton, David T. Clarke, Francesco L. Gervasio, Yibing Shan, David E. Shaw, Daniel J. Rolfe, Peter J. Parker, Marisa L. Martin-Fernandez
Published 2018-10-01