Membrane interaction of bound ligands contributes to the negative binding cooperativity of the EGF receptor.

by Anton Arkhipov, Yibing Shan, Eric T Kim, David E Shaw
Published 2014-07-01

Her2 activation mechanism reflects evolutionary preservation of asymmetric ectodomain dimers in the human EGFR family

by Anton Arkhipov, Yibing Shan, Eric T Kim, Ron O Dror, David E Shaw
Published 2013-07-01

Systematic generation of biophysically detailed models for diverse cortical neuron types

by Nathan W. Gouwens, Jim Berg, David Feng, Staci A. Sorensen, Hongkui Zeng, Michael J. Hawrylycz, Christof Koch, Anton Arkhipov
Published 2018-02-01

BioNet: A Python interface to NEURON for modeling large-scale networks.

by Sergey L Gratiy, Yazan N Billeh, Kael Dai, Catalin Mitelut, David Feng, Nathan W Gouwens, Nicholas Cain, Christof Koch, Costas A Anastassiou, Anton Arkhipov
Published 2018-01-01

Brain Modeling ToolKit: An open source software suite for multiscale modeling of brain circuits.

by Kael Dai, Sergey L Gratiy, Yazan N Billeh, Richard Xu, Binghuang Cai, Nicholas Cain, Atle E Rimehaug, Alexander J Stasik, Gaute T Einevoll, Stefan Mihalas, Christof Koch, Anton Arkhipov
Published 2020-11-01

The SONATA data format for efficient description of large-scale network models.

by Kael Dai, Juan Hernando, Yazan N Billeh, Sergey L Gratiy, Judit Planas, Andrew P Davison, Salvador Dura-Bernal, Padraig Gleeson, Adrien Devresse, Benjamin K Dichter, Michael Gevaert, James G King, Werner A H Van Geit, Arseny V Povolotsky, Eilif Muller, Jean-Denis Courcol, Anton Arkhipov
Published 2020-02-01

EGFR oligomerization organizes kinase-active dimers into competent signalling platforms

by Sarah R. Needham, Selene K. Roberts, Anton Arkhipov, Venkatesh P. Mysore, Christopher J. Tynan, Laura C. Zanetti-Domingues, Eric T. Kim, Valeria Losasso, Dimitrios Korovesis, Michael Hirsch, Daniel J. Rolfe, David T. Clarke, Martyn D. Winn, Alireza Lajevardipour, Andrew H. A. Clayton, Linda J. Pike, Michela Perani, Peter J. Parker, Yibing Shan, David E. Shaw, Marisa L. Martin-Fernandez
Published 2016-10-01

Visual physiology of the layer 4 cortical circuit in silico.

by Anton Arkhipov, Nathan W Gouwens, Yazan N Billeh, Sergey Gratiy, Ramakrishnan Iyer, Ziqiang Wei, Zihao Xu, Reza Abbasi-Asl, Jim Berg, Michael Buice, Nicholas Cain, Nuno da Costa, Saskia de Vries, Daniel Denman, Severine Durand, David Feng, Tim Jarsky, Jérôme Lecoq, Brian Lee, Lu Li, Stefan Mihalas, Gabriel K Ocker, Shawn R Olsen, R Clay Reid, Gilberto Soler-Llavina, Staci A Sorensen, Quanxin Wang, Jack Waters, Massimo Scanziani, Christof Koch
Published 2018-11-01