Chromatin-Bound Cullin-Ring Ligases: Regulatory Roles in DNA Replication and Potential Targeting for Cancer Therapy

by Sang-Min Jang, Christophe E. Redon, Mirit I. Aladjem
Published 2018-03-01

Evaluation of the Gamma-H2AX Assay for Radiation Biodosimetry in a Swine Model

by Christophe E. Redon, William M. Bonner, Mark H. Whitnall, Maria Moroni, Daisuke Maeda
Published 2013-07-01

Regulation of cell cycle drivers by Cullin-RING ubiquitin ligases

by Sang-Min Jang, Christophe E. Redon, Bhushan L. Thakur, Meriam K. Bahta, Mirit I. Aladjem
Published 2020-10-01

The use of gamma-H2AX as a biodosimeter for total-body radiation exposure in non-human primates.

by Christophe E Redon, Asako J Nakamura, Ksenia Gouliaeva, Arifur Rahman, William F Blakely, William M Bonner
Published 2010-11-01

Mitochondrial topoisomerase I is critical for mitochondrial integrity and cellular energy metabolism.

by Céline Douarre, Carole Sourbier, Ilaria Dalla Rosa, Benu Brata Das, Christophe E Redon, Hongliang Zhang, Len Neckers, Yves Pommier
Published 2012-01-01

The replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin

by Sang-Min Jang, Ya Zhang, Koichi Utani, Haiqing Fu, Christophe E. Redon, Anna B. Marks, Owen K. Smith, Catherine J. Redmond, Adrian M. Baris, Danielle A. Tulchinsky, Mirit I. Aladjem
Published 2018-07-01

The histone variant H2A.X is a regulator of the epithelial–mesenchymal transition

by Urbain Weyemi, Christophe E. Redon, Rohini Choudhuri, Towqir Aziz, Daisuke Maeda, Myriem Boufraqech, Palak R. Parekh, Taresh K. Sethi, Manjula Kasoji, Natalie Abrams, Anand Merchant, Vinodh N. Rajapakse, William M. Bonner
Published 2016-02-01

The RepID–CRL4 ubiquitin ligase complex regulates metaphase to anaphase transition via BUB3 degradation

by Sang-Min Jang, Jenny F. Nathans, Haiqing Fu, Christophe E. Redon, Lisa M. Jenkins, Bhushan L. Thakur, Lőrinc S. Pongor, Adrian M. Baris, Jacob M. Gross, Maura J. OʹNeill, Fred E. Indig, Steven D. Cappell, Mirit I. Aladjem
Published 2020-01-01

Phosphorylated fraction of H2AX as a measurement for DNA damage in cancer cells and potential applications of a novel assay.

by Jiuping Ji, Yiping Zhang, Christophe E Redon, William C Reinhold, Alice P Chen, Laura K Fogli, Susan L Holbeck, Ralph E Parchment, Melinda Hollingshead, Joseph E Tomaszewski, Quentin Dudon, Yves Pommier, James H Doroshow, William M Bonner
Published 2017-01-01

A replicator-specific binding protein essential for site-specific initiation of DNA replication in mammalian cells

by Ya Zhang, Liang Huang, Haiqing Fu, Owen K. Smith, Chii Mei Lin, Koichi Utani, Mishal Rao, William C. Reinhold, Christophe E. Redon, Michael Ryan, RyangGuk Kim, Yang You, Harlington Hanna, Yves Boisclair, Qiaoming Long, Mirit I. Aladjem
Published 2016-06-01

Mito-tempol and dexrazoxane exhibit cardioprotective and chemotherapeutic effects through specific protein oxidation and autophagy in a syngeneic breast tumor preclinical model.

by Jennifer S Dickey, Yanira Gonzalez, Baikuntha Aryal, Steven Mog, Asako J Nakamura, Christophe E Redon, Ulrich Baxa, Elliot Rosen, Gang Cheng, Jacek Zielonka, Palak Parekh, Karen P Mason, Joy Joseph, Balaraman Kalyanaraman, William Bonner, Eugene Herman, Emily Shacter, V Ashutosh Rao
Published 2013-01-01

Dynamics of replication origin over-activation

by Haiqing Fu, Christophe E. Redon, Bhushan L. Thakur, Koichi Utani, Robin Sebastian, Sang-Min Jang, Jacob M. Gross, Sara Mosavarpour, Anna B. Marks, Sophie Z. Zhuang, Sarah B. Lazar, Mishal Rao, Shira T. Mencer, Adrian M. Baris, Lorinc S. Pongor, Mirit I. Aladjem
Published 2021-06-01

Histone variant H2A.J accumulates in senescent cells and promotes inflammatory gene expression

by Kévin Contrepois, Clément Coudereau, Bérénice A. Benayoun, Nadine Schuler, Pierre-François Roux, Oliver Bischof, Régis Courbeyrette, Cyril Carvalho, Jean-Yves Thuret, Zhihai Ma, Céline Derbois, Marie-Claire Nevers, Hervé Volland, Christophe E. Redon, William M. Bonner, Jean-François Deleuze, Clotilde Wiel, David Bernard, Michael P. Snyder, Claudia E. Rübe, Robert Olaso, François Fenaille, Carl Mann
Published 2017-05-01