Drugs that target early stages of Onchocerca volvulus: A revisited means to facilitate the elimination goals for onchocerciasis.

by Shabnam Jawahar, Nancy Tricoche, Christina A Bulman, Judy Sakanari, Sara Lustigman
Published 2021-02-01

The Eagle effect in the Wolbachia-worm symbiosis

by Christina A. Bulman, Laura Chappell, Emma Gunderson, Ian Vogel, Brenda Beerntsen, Barton E. Slatko, William Sullivan, Judy A. Sakanari
Published 2021-02-01

De novo identification of toxicants that cause irreparable damage to parasitic nematode intestinal cells.

by Douglas P Jasmer, Bruce A Rosa, Rahul Tyagi, Christina A Bulman, Brenda Beerntsen, Joseph F Urban, Judy Sakanari, Makedonka Mitreva
Published 2020-05-01

Development of a preliminary in vitro drug screening assay based on a newly established culturing system for pre-adult fifth-stage Onchocerca volvulus worms.

by Denis Voronin, Nancy Tricoche, Shabnam Jawahar, Michael Shlossman, Christina A Bulman, Chelsea Fischer, Michael T Suderman, Judy A Sakanari, Sara Lustigman
Published 2019-01-01

Efficacy of subcutaneous doses and a new oral amorphous solid dispersion formulation of flubendazole on male jirds (Meriones unguiculatus) infected with the filarial nematode Brugi...

by Chelsea Fischer, Iosune Ibiricu Urriza, Christina A Bulman, K C Lim, Jiri Gut, Sophie Lachau-Durand, Marc Engelen, Ludo Quirynen, Fetene Tekle, Benny Baeten, Brenda Beerntsen, Sara Lustigman, Judy Sakanari
Published 2019-01-01

Repurposing Auranofin and Evaluation of a New Gold(I) Compound for the Search of Treatment of Human and Cattle Parasitic Diseases: From Protozoa to Helminth Infections

by Liwen Feng, Sébastien Pomel, Perle Latre de Late, Alexandre Taravaud, Philippe M. Loiseau, Louis Maes, Fidelis Cho-Ngwa, Christina A. Bulman, Chelsea Fischer, Judy A. Sakanari, Peter D. Ziniel, David L. Williams, Elisabeth Davioud-Charvet
Published 2020-11-01

The endosymbiont Wolbachia rebounds following antibiotic treatment.

by Emma L Gunderson, Ian Vogel, Laura Chappell, Christina A Bulman, K C Lim, Mona Luo, Jeffrey D Whitman, Chris Franklin, Young-Jun Choi, Emilie Lefoulon, Travis Clark, Brenda Beerntsen, Barton Slatko, Makedonka Mitreva, William Sullivan, Judy A Sakanari
Published 2020-07-01

An Integrated Approach to Identify New Anti-Filarial Leads to Treat River Blindness, a Neglected Tropical Disease

by Rahul Tyagi, Christina A. Bulman, Fidelis Cho-Ngwa, Chelsea Fischer, Chris Marcellino, Michelle R. Arkin, James H. McKerrow, Case W. McNamara, Matthew Mahoney, Nancy Tricoche, Shabnam Jawahar, James W. Janetka, Sara Lustigman, Judy Sakanari, Makedonka Mitreva
Published 2021-01-01

Short-course quinazoline drug treatments are effective in the Litomosoides sigmodontis and Brugia pahangi jird models

by Marc P. Hübner, Emma Gunderson, Ian Vogel, Christina A. Bulman, K.C. Lim, Marianne Koschel, Alexandra Ehrens, Stefan J. Frohberger, Martina Fendler, Nancy Tricoche, Denis Voronin, Andrew Steven, Victor Chi, Malina A. Bakowski, Ashley K. Woods, H. Michael Petrassi, Case W. McNamara, Brenda Beerntsen, Laura Chappell, William Sullivan, Mark J. Taylor, Joseph D. Turner, Achim Hoerauf, Sara Lustigman, Judy A. Sakanari
Published 2020-04-01

Repurposing auranofin as a lead candidate for treatment of lymphatic filariasis and onchocerciasis.

by Christina A Bulman, Chelsea M Bidlow, Sara Lustigman, Fidelis Cho-Ngwa, David Williams, Alberto A Rascón, Nancy Tricoche, Moses Samje, Aaron Bell, Brian Suzuki, K C Lim, Nonglak Supakorndej, Prasit Supakorndej, Alan R Wolfe, Giselle M Knudsen, Steven Chen, Chris Wilson, Kean-Hooi Ang, Michelle Arkin, Jiri Gut, Chris Franklin, Chris Marcellino, James H McKerrow, Anjan Debnath, Judy A Sakanari
Published 2015-02-01