Harnessing the Complete Repertoire of Conventional Dendritic Cell Functions for Cancer Immunotherapy

by Lukas Amon, Lukas Hatscher, Lukas Heger, Diana Dudziak, Christian H.K. Lehmann
Published 2020-07-01

Siglec-H-Deficient Mice Show Enhanced Type I IFN Responses, but Do Not Develop Autoimmunity After Influenza or LCMV Infections

by Nadine Szumilas, Odilia B. J. Corneth, Christian H. K. Lehmann, Christian H. K. Lehmann, Christian H. K. Lehmann, Heike Schmitt, Svenia Cunz, Jolie G. Cullen, Talyn Chu, Anita Marosan, Attila Mócsai, Vladimir Benes, Dietmar Zehn, Diana Dudziak, Diana Dudziak, Diana Dudziak, Rudi W. Hendriks, Lars Nitschke, Lars Nitschke
Published 2021-08-01

Direct Delivery of Antigens to Dendritic Cells via Antibodies Specific for Endocytic Receptors as a Promising Strategy for Future Therapies

by Christian H. K. Lehmann, Lukas Heger, Gordon F. Heidkamp, Anna Baranska, Jennifer J. Lühr, Alana Hoffmann, Diana Dudziak
Published 2016-03-01

Mast-Cell-Derived TNF Amplifies CD8+ Dendritic Cell Functionality and CD8+ T Cell Priming

by Jan Dudeck, Shanawaz Mohammed Ghouse, Christian H.K. Lehmann, Anja Hoppe, Nadja Schubert, Sergei A. Nedospasov, Diana Dudziak, Anne Dudeck
Published 2015-10-01

Th17 Cell-Mediated Colitis Is Positively Regulated by Interferon Regulatory Factor 4 in a T Cell-Extrinsic Manner

by Vera Buchele, Vera Buchele, Patrick Konein, Patrick Konein, Tina Vogler, Tina Vogler, Timo Kunert, Timo Kunert, Karin Enderle, Karin Enderle, Hanif Khan, Hanif Khan, Maike Büttner-Herold, Christian H. K. Lehmann, Christian H. K. Lehmann, Lukas Amon, Lukas Amon, Stefan Wirtz, Stefan Wirtz, Diana Dudziak, Diana Dudziak, Markus F. Neurath, Markus F. Neurath, Clemens Neufert, Clemens Neufert, Kai Hildner, Kai Hildner
Published 2021-01-01

Cathepsin S provokes interleukin-6 (IL-6) trans-signaling through cleavage of the IL-6 receptor in vitro

by Charlotte M. Flynn, Yvonne Garbers, Stefan Düsterhöft, Rielana Wichert, Juliane Lokau, Christian H. K. Lehmann, Diana Dudziak, Bernd Schröder, Christoph Becker-Pauly, Stefan Rose-John, Samadhi Aparicio-Siegmund, Christoph Garbers
Published 2020-12-01

CLEC10A Is a Specific Marker for Human CD1c+ Dendritic Cells and Enhances Their Toll-Like Receptor 7/8-Induced Cytokine Secretion

by Lukas Heger, Silke Balk, Jennifer J. Lühr, Gordon F. Heidkamp, Christian H. K. Lehmann, Lukas Hatscher, Ariawan Purbojo, Arndt Hartmann, Fayna Garcia-Martin, Shin-Ichiro Nishimura, Robert Cesnjevar, Falk Nimmerjahn, Diana Dudziak
Published 2018-04-01

Environmental signals rather than layered ontogeny imprint the function of type 2 conventional dendritic cells in young and adult mice

by Nikos E. Papaioannou, Natallia Salei, Stephan Rambichler, Kaushikk Ravi, Jelena Popovic, Vanessa Küntzel, Christian H. K. Lehmann, Remi Fiancette, Johanna Salvermoser, Dominika W. Gajdasik, Ramona Mettler, Denise Messerer, Joana Carrelha, Caspar Ohnmacht, Dirk Haller, Ralf Stumm, Tobias Straub, Sten Eirik W. Jacobsen, Christian Schulz, David R. Withers, Gunnar Schotta, Diana Dudziak, Barbara U. Schraml
Published 2021-01-01

Maturation of Monocyte-Derived DCs Leads to Increased Cellular Stiffness, Higher Membrane Fluidity, and Changed Lipid Composition

by Jennifer J. Lühr, Jennifer J. Lühr, Jennifer J. Lühr, Nils Alex, Lukas Amon, Martin Kräter, Martin Kräter, Markéta Kubánková, Markéta Kubánková, Erdinc Sezgin, Erdinc Sezgin, Christian H. K. Lehmann, Lukas Heger, Gordon F. Heidkamp, Gordon F. Heidkamp, Ana-Sunčana Smith, Vasily Zaburdaev, Vasily Zaburdaev, Vasily Zaburdaev, Rainer A. Böckmann, Ilya Levental, Michael L. Dustin, Christian Eggeling, Christian Eggeling, Christian Eggeling, Jochen Guck, Jochen Guck, Diana Dudziak, Diana Dudziak, Diana Dudziak, Diana Dudziak
Published 2020-11-01